5mfx

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(New page: '''Unreleased structure''' The entry 5mfx is ON HOLD until Paper Publication Authors: Jenkins, H.T., Ge, M., Chechik, M., Greive, S.J., Antson, A.A. Description: Zika NS3 helicase:RNA ...)
Current revision (18:42, 1 November 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5mfx is ON HOLD until Paper Publication
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==Zika NS3 helicase:RNA complex==
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<StructureSection load='5mfx' size='340' side='right'caption='[[5mfx]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5mfx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Zika_virus Zika virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MFX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MFX FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.598&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mfx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mfx OCA], [https://pdbe.org/5mfx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mfx RCSB], [https://www.ebi.ac.uk/pdbsum/5mfx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mfx ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A146CJH9_ZIKV A0A146CJH9_ZIKV] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859]
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Authors: Jenkins, H.T., Ge, M., Chechik, M., Greive, S.J., Antson, A.A.
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==See Also==
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*[[Virus protease 3D structures|Virus protease 3D structures]]
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Description: Zika NS3 helicase:RNA complex
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__TOC__
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[[Category: Unreleased Structures]]
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</StructureSection>
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[[Category: Greive, S.J]]
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[[Category: Large Structures]]
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[[Category: Antson, A.A]]
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[[Category: Zika virus]]
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[[Category: Chechik, M]]
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[[Category: Antson AA]]
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[[Category: Ge, M]]
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[[Category: Chechik M]]
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[[Category: Jenkins, H.T]]
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[[Category: Ge M]]
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[[Category: Greive SJ]]
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[[Category: Jenkins HT]]

Current revision

Zika NS3 helicase:RNA complex

PDB ID 5mfx

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