1qd7

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[[Image:1qd7.gif|left|200px]]
 
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{{Structure
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==PARTIAL MODEL FOR 30S RIBOSOMAL SUBUNIT==
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|PDB= 1qd7 |SIZE=350|CAPTION= <scene name='initialview01'>1qd7</scene>, resolution 5.5&Aring;
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<StructureSection load='1qd7' size='340' side='right'caption='[[1qd7]], [[Resolution|resolution]] 5.50&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=N:ANY+5&#39;-MONOPHOSPHATE+NUCLEOTIDE'>N</scene>, <scene name='pdbligand=UNK:UNKNOWN'>UNK</scene>
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<table><tr><td colspan='2'>[[1qd7]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QD7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QD7 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 5.5&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=N:ANY+5-MONOPHOSPHATE+NUCLEOTIDE'>N</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qd7 OCA], [https://pdbe.org/1qd7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qd7 RCSB], [https://www.ebi.ac.uk/pdbsum/1qd7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qd7 ProSAT]</span></td></tr>
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|RELATEDENTRY=[[1pkp|1PKP]], [[1ris|1RIS]], [[1rss|1RSS]], [[1a32|1A32]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qd7 OCA], [http://www.ebi.ac.uk/pdbsum/1qd7 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1qd7 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/RS4_GEOSE RS4_GEOSE] One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity).[HAMAP-Rule:MF_01306_B] With S5 and S12 plays an important role in translational accuracy (By similarity).[HAMAP-Rule:MF_01306_B]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qd/1qd7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qd7 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The 30S ribosomal subunit binds messenger RNA and the anticodon stem-loop of transfer RNA during protein synthesis. A crystallographic analysis of the structure of the subunit from the bacterium Thermus thermophilus is presented. At a resolution of 5.5 A, the phosphate backbone of the ribosomal RNA is visible, as are the alpha-helices of the ribosomal proteins, enabling double-helical regions of RNA to be identified throughout the subunit, all seven of the small-subunit proteins of known crystal structure to be positioned in the electron density map, and the fold of the entire central domain of the small-subunit ribosomal RNA to be determined.
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'''PARTIAL MODEL FOR 30S RIBOSOMAL SUBUNIT'''
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Structure of a bacterial 30S ribosomal subunit at 5.5 A resolution.,Clemons WM Jr, May JL, Wimberly BT, McCutcheon JP, Capel MS, Ramakrishnan V Nature. 1999 Aug 26;400(6747):833-40. PMID:10476960<ref>PMID:10476960</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 1qd7" style="background-color:#fffaf0;"></div>
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==Overview==
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==See Also==
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The 30S ribosomal subunit binds messenger RNA and the anticodon stem-loop of transfer RNA during protein synthesis. A crystallographic analysis of the structure of the subunit from the bacterium Thermus thermophilus is presented. At a resolution of 5.5 A, the phosphate backbone of the ribosomal RNA is visible, as are the alpha-helices of the ribosomal proteins, enabling double-helical regions of RNA to be identified throughout the subunit, all seven of the small-subunit proteins of known crystal structure to be positioned in the electron density map, and the fold of the entire central domain of the small-subunit ribosomal RNA to be determined.
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*[[Ribosomal protein S15|Ribosomal protein S15]]
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*[[Ribosomal protein S17|Ribosomal protein S17]]
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==About this Structure==
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*[[Ribosomal protein S20|Ribosomal protein S20]]
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1QD7 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QD7 OCA].
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*[[Ribosomal protein S5|Ribosomal protein S5]]
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*[[Ribosomal protein S6|Ribosomal protein S6]]
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==Reference==
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*[[Ribosomal protein S7|Ribosomal protein S7]]
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Structure of a bacterial 30S ribosomal subunit at 5.5 A resolution., Clemons WM Jr, May JL, Wimberly BT, McCutcheon JP, Capel MS, Ramakrishnan V, Nature. 1999 Aug 26;400(6747):833-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10476960 10476960]
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*[[Ribosomal protein S8|Ribosomal protein S8]]
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[[Category: Protein complex]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Capel, M S.]]
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[[Category: Capel MS]]
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[[Category: Jr., W M.Clemons.]]
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[[Category: Clemons Jr WM]]
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[[Category: May, J L.C.]]
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[[Category: May JLC]]
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[[Category: McCutcheon, J P.]]
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[[Category: McCutcheon JP]]
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[[Category: Ramakrishnan, V.]]
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[[Category: Ramakrishnan V]]
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[[Category: Wimberly, B T.]]
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[[Category: Wimberly BT]]
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[[Category: 30s ribosomal subunit]]
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[[Category: low resolution model]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:12:05 2008''
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Current revision

PARTIAL MODEL FOR 30S RIBOSOMAL SUBUNIT

PDB ID 1qd7

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