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5g49

From Proteopedia

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Crystal structure of the Arabodopsis thaliana histone-fold dimer L1L NF-YC3

Structural highlights

5g49 is a 2 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.3Å
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NFYB6_ARATH Component of the NF-Y/HAP transcription factor complex. The NF-Y complex stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters. Plays a role in the regulation of the embryogenesis. Involved in the abscisic acid (ABA) signaling pathway.^[1] ^[2]

Publication Abstract from PubMed

The structural analysis of the L1L/NF-YC3 histone dimer from A. thaliana shows that it can trimerize and bind to the CCAAT box. Specific sequence and structural features at the protein/DNA interface, in particular the presence of a Asp-His pair, help explain the molecular mechanisms of LEC1/L1L activity as a bona fide mammalian-like NF-YB.

Crystal structure of the Arabidopsis thaliana L1L/NF-YC3 histone-fold dimer reveals specificities of the LEC1 family of NF-Y subunits in plants.,Gnesutta N, Saad D, Chaves-Sanjuan A, Mantovani R, Nardini M Mol Plant. 2016 Nov 18. pii: S1674-2052(16)30276-3. doi:, 10.1016/j.molp.2016.11.006. PMID:27871811^[3]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Kwong RW, Bui AQ, Lee H, Kwong LW, Fischer RL, Goldberg RB, Harada JJ. LEAFY COTYLEDON1-LIKE defines a class of regulators essential for embryo development. Plant Cell. 2003 Jan;15(1):5-18. PMID:12509518
↑ Warpeha KM, Upadhyay S, Yeh J, Adamiak J, Hawkins SI, Lapik YR, Anderson MB, Kaufman LS. The GCR1, GPA1, PRN1, NF-Y signal chain mediates both blue light and abscisic acid responses in Arabidopsis. Plant Physiol. 2007 Apr;143(4):1590-600. Epub 2007 Feb 23. PMID:17322342 doi:http://dx.doi.org/10.1104/pp.106.089904
↑ Gnesutta N, Saad D, Chaves-Sanjuan A, Mantovani R, Nardini M. Crystal structure of the Arabidopsis thaliana L1L/NF-YC3 histone-fold dimer reveals specificities of the LEC1 family of NF-Y subunits in plants. Mol Plant. 2016 Nov 18. pii: S1674-2052(16)30276-3. doi:, 10.1016/j.molp.2016.11.006. PMID:27871811 doi:http://dx.doi.org/10.1016/j.molp.2016.11.006

1 Structural highlights
2 Function
3 Publication Abstract from PubMed
4 See Also
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5g49"

@@ Line 1: / Line 1: @@
 ==Crystal structure of the Arabodopsis thaliana histone-fold dimer L1L NF-YC3==
-<StructureSection load='5g49' size='340' side='right' caption='[[5g49]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+<StructureSection load='5g49' size='340' side='right'caption='[[5g49]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5g49]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G49 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5G49 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5g49]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G49 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5G49 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5g49 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g49 OCA], [http://pdbe.org/5g49 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g49 RCSB], [http://www.ebi.ac.uk/pdbsum/5g49 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5g49 ProSAT]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5g49 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g49 OCA], [https://pdbe.org/5g49 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5g49 RCSB], [https://www.ebi.ac.uk/pdbsum/5g49 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5g49 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/NFYB6_ARATH NFYB6_ARATH]] Component of the NF-Y/HAP transcription factor complex. The NF-Y complex stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters. Plays a role in the regulation of the embryogenesis. Involved in the abscisic acid (ABA) signaling pathway.<ref>PMID:12509518</ref> <ref>PMID:17322342</ref>  [[http://www.uniprot.org/uniprot/NFYC3_ARATH NFYC3_ARATH]] Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters.
+[https://www.uniprot.org/uniprot/NFYB6_ARATH NFYB6_ARATH] Component of the NF-Y/HAP transcription factor complex. The NF-Y complex stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters. Plays a role in the regulation of the embryogenesis. Involved in the abscisic acid (ABA) signaling pathway.<ref>PMID:12509518</ref> <ref>PMID:17322342</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 18: / Line 19: @@
 </div>
 <div class="pdbe-citations 5g49" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Nuclear transcription factor Y|Nuclear transcription factor Y]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Chaves-Sanjuan, A]]
+[[Category: Arabidopsis thaliana]]
-[[Category: Gnesutta, N]]
+[[Category: Large Structures]]
-[[Category: Mantovani, R]]
+[[Category: Chaves-Sanjuan A]]
-[[Category: Nardini, M]]
+[[Category: Gnesutta N]]
-[[Category: Saad, D]]
+[[Category: Mantovani R]]
-[[Category: Ccaat box- binding transcription factor]]
+[[Category: Nardini M]]
-[[Category: Histone-fold domain]]
+[[Category: Saad D]]
-[[Category: Nf-y]]
-[[Category: Transcription]]
-[[Category: Transcription factor]]

5g49

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Current revision

Crystal structure of the Arabodopsis thaliana histone-fold dimer L1L NF-YC3

Structural highlights

Function

Publication Abstract from PubMed

See Also

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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