We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

5m62

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (18:27, 1 November 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Structure of the Mus musclus Langerin carbohydrate recognition domain in complex with glucose==
==Structure of the Mus musclus Langerin carbohydrate recognition domain in complex with glucose==
-
<StructureSection load='5m62' size='340' side='right' caption='[[5m62]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
+
<StructureSection load='5m62' size='340' side='right'caption='[[5m62]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5m62]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M62 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M62 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5m62]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5M62 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5k8y|5k8y]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m62 OCA], [http://pdbe.org/5m62 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m62 RCSB], [http://www.ebi.ac.uk/pdbsum/5m62 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m62 ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5m62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m62 OCA], [https://pdbe.org/5m62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5m62 RCSB], [https://www.ebi.ac.uk/pdbsum/5m62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5m62 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/CLC4K_MOUSE CLC4K_MOUSE]] Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells.<ref>PMID:11777972</ref> <ref>PMID:18322168</ref>
+
[https://www.uniprot.org/uniprot/CLC4K_MOUSE CLC4K_MOUSE] Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells.<ref>PMID:11777972</ref> <ref>PMID:18322168</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Aretz, J]]
+
[[Category: Large Structures]]
-
[[Category: Loll, B]]
+
[[Category: Mus musculus]]
-
[[Category: Rademacher, C]]
+
[[Category: Aretz J]]
-
[[Category: Wahl, M C]]
+
[[Category: Loll B]]
-
[[Category: C-type lectin]]
+
[[Category: Rademacher C]]
-
[[Category: Calcium binding]]
+
[[Category: Wahl MC]]
-
[[Category: Carbohydrate binding protein]]
+
-
[[Category: Crd domain]]
+
-
[[Category: Glycoprotein]]
+
-
[[Category: Immune system]]
+
-
[[Category: Lectin]]
+

Current revision

Structure of the Mus musclus Langerin carbohydrate recognition domain in complex with glucose

PDB ID 5m62

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5m62"
Personal tools