5mkt
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of mouse prorenin== | |
| + | <StructureSection load='5mkt' size='340' side='right'caption='[[5mkt]], [[Resolution|resolution]] 3.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5mkt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MKT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MKT FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mkt OCA], [https://pdbe.org/5mkt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mkt RCSB], [https://www.ebi.ac.uk/pdbsum/5mkt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mkt ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RENI1_MOUSE RENI1_MOUSE] Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. | ||
| - | + | ==See Also== | |
| - | + | *[[Renin|Renin]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Read | + | [[Category: Large Structures]] |
| - | [[Category: Yan | + | [[Category: Mus musculus]] |
| + | [[Category: Read R]] | ||
| + | [[Category: Yan Y]] | ||
Current revision
Crystal structure of mouse prorenin
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