5u1y
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist GW791343== | |
| + | <StructureSection load='5u1y' size='340' side='right'caption='[[5u1y]], [[Resolution|resolution]] 3.30Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5u1y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ailuropoda_melanoleuca Ailuropoda melanoleuca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5U1Y FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7RS:N~2~-(3,4-DIFLUOROPHENYL)-N-{2-METHYL-5-[(PIPERAZIN-1-YL)METHYL]PHENYL}GLYCINAMIDE'>7RS</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5u1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u1y OCA], [https://pdbe.org/5u1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5u1y RCSB], [https://www.ebi.ac.uk/pdbsum/5u1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5u1y ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/G1M6C4_AILME G1M6C4_AILME] Receptor for ATP that acts as a ligand-gated ion channel.[RuleBase:RU000681] | ||
| - | + | ==See Also== | |
| - | + | *[[Ion channels 3D structures|Ion channels 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Ailuropoda melanoleuca]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Karasawa A]] | ||
| + | [[Category: Kawate T]] | ||
Current revision
Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist GW791343
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