5lxp
From Proteopedia
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==Human PARP14 (ARTD8), catalytic fragment in complex with inhibitor H5== | ==Human PARP14 (ARTD8), catalytic fragment in complex with inhibitor H5== | ||
- | <StructureSection load='5lxp' size='340' side='right' caption='[[5lxp]], [[Resolution|resolution]] 2.07Å' scene=''> | + | <StructureSection load='5lxp' size='340' side='right'caption='[[5lxp]], [[Resolution|resolution]] 2.07Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[5lxp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LXP OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5lxp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LXP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LXP FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7AG:~{N}-(3-AMINOCARBONYLPHENYL)-~{N}-[[1-[(2~{R})-2-PHENYLPROPYL]-1,2,3-TRIAZOL-4-YL]METHYL]PENTANEDIAMIDE'>7AG</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.07Å</td></tr> |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7AG:~{N}-(3-AMINOCARBONYLPHENYL)-~{N}-[[1-[(2~{R})-2-PHENYLPROPYL]-1,2,3-TRIAZOL-4-YL]METHYL]PENTANEDIAMIDE'>7AG</scene></td></tr> | |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lxp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lxp OCA], [https://pdbe.org/5lxp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lxp RCSB], [https://www.ebi.ac.uk/pdbsum/5lxp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lxp ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/PAR14_HUMAN PAR14_HUMAN] Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5lxp" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5lxp" style="background-color:#fffaf0;"></div> | ||
+ | |||
+ | ==See Also== | ||
+ | *[[Poly(ADP-ribose) polymerase 3D structures|Poly(ADP-ribose) polymerase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Homo sapiens]] |
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Karlberg T]] |
- | [[Category: | + | [[Category: Schuler H]] |
- | [[Category: | + | [[Category: Thorsell AG]] |
- | + | ||
- | + |
Current revision
Human PARP14 (ARTD8), catalytic fragment in complex with inhibitor H5
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