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4n6m
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==Crystal structure of human cystatin E/M produced in LEXSY== | ==Crystal structure of human cystatin E/M produced in LEXSY== | ||
| - | <StructureSection load='4n6m' size='340' side='right' caption='[[4n6m]], [[Resolution|resolution]] 2.90Å' scene=''> | + | <StructureSection load='4n6m' size='340' side='right'caption='[[4n6m]], [[Resolution|resolution]] 2.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4n6m]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N6M OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4n6m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N6M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N6M FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n6m OCA], [https://pdbe.org/4n6m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n6m RCSB], [https://www.ebi.ac.uk/pdbsum/4n6m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n6m ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CYTM_HUMAN CYTM_HUMAN] Shows moderate inhibition of cathepsin B but is not active against cathepsin C. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Brandstetter H]] |
| - | [[Category: | + | [[Category: Dall E]] |
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Current revision
Crystal structure of human cystatin E/M produced in LEXSY
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