4kqo

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==Crystal structure of penicillin-binding protein 3 from pseudomonas aeruginosa in complex with piperacillin==
==Crystal structure of penicillin-binding protein 3 from pseudomonas aeruginosa in complex with piperacillin==
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<StructureSection load='4kqo' size='340' side='right' caption='[[4kqo]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
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<StructureSection load='4kqo' size='340' side='right'caption='[[4kqo]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4kqo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KQO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KQO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4kqo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KQO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KQO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=JPP:PIPERACILLIN+(OPEN+FORM)'>JPP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.31&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4kqq|4kqq]], [[4kqr|4kqr]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=JPP:PIPERACILLIN+(OPEN+FORM)'>JPP</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ftsI, PA4418 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kqo OCA], [https://pdbe.org/4kqo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kqo RCSB], [https://www.ebi.ac.uk/pdbsum/4kqo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kqo ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kqo OCA], [http://pdbe.org/4kqo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kqo RCSB], [http://www.ebi.ac.uk/pdbsum/4kqo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kqo ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FTSI_PSEAE FTSI_PSEAE] Catalyzes cross-linking of the peptidoglycan cell wall at the division septum (By similarity). Binds penicillin (PubMed:20580675).[HAMAP-Rule:MF_02080]<ref>PMID:20580675</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Penicillin-binding protein|Penicillin-binding protein]]
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*[[Penicillin-binding protein 3D structures|Penicillin-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Pseae]]
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[[Category: Large Structures]]
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[[Category: Nettleship, J E]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Owens, R J]]
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[[Category: Nettleship JE]]
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[[Category: Ren, J]]
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[[Category: Owens RJ]]
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[[Category: Stuart, D I]]
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[[Category: Ren J]]
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[[Category: Biosynthetic protein-antibiotic complex]]
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[[Category: Stuart DI]]
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[[Category: Cell wall biosynthesis]]
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[[Category: Out periplasmic membrane]]
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[[Category: Penicillin-binding protein]]
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[[Category: Piperacillin]]
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[[Category: Transpeptidase]]
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Current revision

Crystal structure of penicillin-binding protein 3 from pseudomonas aeruginosa in complex with piperacillin

PDB ID 4kqo

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