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1r7o

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[[Image:1r7o.gif|left|200px]]
 
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{{Structure
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==Crystal Structure of apo-mannanase 26A from Psudomonas cellulosa==
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|PDB= 1r7o |SIZE=350|CAPTION= <scene name='initialview01'>1r7o</scene>, resolution 1.85&Aring;
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<StructureSection load='1r7o' size='340' side='right'caption='[[1r7o]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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<table><tr><td colspan='2'>[[1r7o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cellvibrio_japonicus Cellvibrio japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R7O FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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|GENE= Man26A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=155077 Cellvibrio japonicus])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r7o OCA], [https://pdbe.org/1r7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r7o RCSB], [https://www.ebi.ac.uk/pdbsum/1r7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r7o ProSAT]</span></td></tr>
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|RELATEDENTRY=[[1j9y|1j9y]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1r7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r7o OCA], [http://www.ebi.ac.uk/pdbsum/1r7o PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1r7o RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/MANA_CELJU MANA_CELJU] Hydrolyzes mannan and galactomannan, but displays little activity towards other polysaccharides located in the plant cell wall. Appears to act in synergy with alpha-galactosidase (AgaA) to elicit hydrolysis of galactomannan. Preferentially hydrolyzes the larger oligosaccharides and has greater activity against non-substituted polysaccharides.<ref>PMID:7848261</ref> <ref>PMID:11064195</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r7/1r7o_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r7o ConSurf].
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<div style="clear:both"></div>
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'''Crystal Structure of apo-mannanase 26A from Psudomonas cellulosa'''
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==See Also==
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*[[Mannosidase 3D structures|Mannosidase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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1R7O is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Cellvibrio_japonicus Cellvibrio japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R7O OCA].
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__TOC__
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</StructureSection>
[[Category: Cellvibrio japonicus]]
[[Category: Cellvibrio japonicus]]
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[[Category: Mannan endo-1,4-beta-mannosidase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Oakley AJ]]
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[[Category: Oakley, A J.]]
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[[Category: Wilce MCJ]]
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[[Category: Wilce, M C.J.]]
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[[Category: endo beta1-4 mannanase]]
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[[Category: mannan degrading enzyme]]
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[[Category: mannanase 26a]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:24:24 2008''
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Current revision

Crystal Structure of apo-mannanase 26A from Psudomonas cellulosa

PDB ID 1r7o

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