5mr9

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m (Protected "5mr9" [edit=sysop:move=sysop])
Current revision (17:46, 8 November 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5mr9 is ON HOLD
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==Ligand-receptor complex.==
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<StructureSection load='5mr9' size='340' side='right'caption='[[5mr9]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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Authors: Sandmark, J., Oster, L., Aagaard, A., Roth, R.G., Dahl, G.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5mr9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MR9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MR9 FirstGlance]. <br>
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Description: Ligand-receptor complex.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mr9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mr9 OCA], [https://pdbe.org/5mr9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mr9 RCSB], [https://www.ebi.ac.uk/pdbsum/5mr9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mr9 ProSAT]</span></td></tr>
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[[Category: Aagaard, A]]
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</table>
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[[Category: Oster, L]]
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== Disease ==
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[[Category: Dahl, G]]
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[https://www.uniprot.org/uniprot/NRTN_HUMAN NRTN_HUMAN] Hirschsprung disease. Genetic variations in NRTN may contribute to Hirschsprung disease, in association with mutations of RET gene, and possibly mutations in other loci. Hirschsprung disease is a disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.<ref>PMID:9700200</ref>
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[[Category: Roth, R.G]]
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== Function ==
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[[Category: Sandmark, J]]
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[https://www.uniprot.org/uniprot/NRTN_HUMAN NRTN_HUMAN] Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Aagaard A]]
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[[Category: Dahl G]]
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[[Category: Oster L]]
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[[Category: Roth RG]]
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[[Category: Sandmark J]]

Current revision

Ligand-receptor complex.

PDB ID 5mr9

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