2yjn

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==Structure of the glycosyltransferase EryCIII from the erythromycin biosynthetic pathway, in complex with its activating partner, EryCII==
==Structure of the glycosyltransferase EryCIII from the erythromycin biosynthetic pathway, in complex with its activating partner, EryCII==
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<StructureSection load='2yjn' size='340' side='right' caption='[[2yjn]], [[Resolution|resolution]] 3.09&Aring;' scene=''>
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<StructureSection load='2yjn' size='340' side='right'caption='[[2yjn]], [[Resolution|resolution]] 3.09&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2yjn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"actinomyces_erythreus"_(sic)_waksman_1923 "actinomyces erythreus" (sic) waksman 1923]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YJN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YJN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2yjn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharopolyspora_erythraea_NRRL_2338 Saccharopolyspora erythraea NRRL 2338]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YJN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YJN FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yjn OCA], [http://pdbe.org/2yjn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yjn RCSB], [http://www.ebi.ac.uk/pdbsum/2yjn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yjn ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.091&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yjn OCA], [https://pdbe.org/2yjn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yjn RCSB], [https://www.ebi.ac.uk/pdbsum/2yjn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yjn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ERYC3_SACEN ERYC3_SACEN]] Catalyzes the conversion of alpha-L-mycarosylerythronolide B into erythromycin D in the erythromycin biosynthesis pathway.<ref>PMID:15303858</ref> [[http://www.uniprot.org/uniprot/ERYC2_SACEN ERYC2_SACEN]] Involved in the erythromycin biosynthesis pathway. Acts by forming a complex and stabilizing the desosaminyl transferase EryCIII.<ref>PMID:22056329</ref>
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[https://www.uniprot.org/uniprot/ERYC3_SACEN ERYC3_SACEN] Catalyzes the conversion of alpha-L-mycarosylerythronolide B into erythromycin D in the erythromycin biosynthesis pathway.<ref>PMID:15303858</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Glycosyltransferase|Glycosyltransferase]]
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*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Fernandez, M J]]
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[[Category: Large Structures]]
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[[Category: Gay, N J]]
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[[Category: Saccharopolyspora erythraea NRRL 2338]]
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[[Category: Leadlay, P F]]
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[[Category: Fernandez MJ]]
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[[Category: Luisi, B F]]
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[[Category: Gay NJ]]
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[[Category: Matsumura, H]]
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[[Category: Leadlay PF]]
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[[Category: Moncrieffe, M C]]
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[[Category: Luisi BF]]
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[[Category: Spiteller, D]]
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[[Category: Matsumura H]]
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[[Category: Cytochrome p450]]
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[[Category: Moncrieffe MC]]
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[[Category: Transferase]]
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[[Category: Spiteller D]]

Current revision

Structure of the glycosyltransferase EryCIII from the erythromycin biosynthetic pathway, in complex with its activating partner, EryCII

PDB ID 2yjn

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