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4oso

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==The crystal structure of landomycin C-6 ketoreductase LanV with bound NADP and rabelomycin==
==The crystal structure of landomycin C-6 ketoreductase LanV with bound NADP and rabelomycin==
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<StructureSection load='4oso' size='340' side='right' caption='[[4oso]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='4oso' size='340' side='right'caption='[[4oso]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4oso]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OSO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OSO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4oso]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_cyanogenus Streptomyces cyanogenus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OSO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2V4:RABELOMYCIN'>2V4</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4kwh|4kwh]], [[4kwi|4kwi]], [[4osp|4osp]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2V4:RABELOMYCIN'>2V4</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oso OCA], [http://pdbe.org/4oso PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4oso RCSB], [http://www.ebi.ac.uk/pdbsum/4oso PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4oso ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4oso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oso OCA], [https://pdbe.org/4oso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oso RCSB], [https://www.ebi.ac.uk/pdbsum/4oso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oso ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9ZGC1_STRCY Q9ZGC1_STRCY]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Metsa-Ketela, M]]
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[[Category: Large Structures]]
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[[Category: Niiranen, L]]
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[[Category: Streptomyces cyanogenus]]
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[[Category: Paananen, P]]
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[[Category: Metsa-Ketela M]]
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[[Category: Patrikainen, P]]
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[[Category: Niiranen L]]
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[[Category: Ketoreductase]]
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[[Category: Paananen P]]
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[[Category: Nadph binding]]
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[[Category: Patrikainen P]]
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[[Category: Oxidoreductase-antibiotic complex]]
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[[Category: Rossmann fold]]
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Current revision

The crystal structure of landomycin C-6 ketoreductase LanV with bound NADP and rabelomycin

PDB ID 4oso

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