3wsa

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:25, 8 November 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole==
==The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole==
-
<StructureSection load='3wsa' size='340' side='right' caption='[[3wsa]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
+
<StructureSection load='3wsa' size='340' side='right'caption='[[3wsa]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3wsa]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WSA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WSA FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3wsa]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WSA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WSA FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RWZ:N-[(2Z)-3,7-DIMETHYLOCTA-2,6-DIEN-1-YL]-N-[(1R,3S,5R,7R)-TRICYCLO[3.3.1.1~3,7~]DEC-2-YL]ETHANE-1,2-DIAMINE'>RWZ</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wsb|3wsb]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RWZ:N-[(2Z)-3,7-DIMETHYLOCTA-2,6-DIEN-1-YL]-N-[(1R,3S,5R,7R)-TRICYCLO[3.3.1.1~3,7~]DEC-2-YL]ETHANE-1,2-DIAMINE'>RWZ</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Squalene_synthase Squalene synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.21 2.5.1.21] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wsa OCA], [https://pdbe.org/3wsa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wsa RCSB], [https://www.ebi.ac.uk/pdbsum/3wsa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wsa ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wsa OCA], [http://pdbe.org/3wsa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wsa RCSB], [http://www.ebi.ac.uk/pdbsum/3wsa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wsa ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/FDFT_HUMAN FDFT_HUMAN]
==See Also==
==See Also==
Line 14: Line 15:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Squalene synthase]]
+
[[Category: Homo sapiens]]
-
[[Category: Guo, R T]]
+
[[Category: Large Structures]]
-
[[Category: Huang, C H]]
+
[[Category: Guo RT]]
-
[[Category: Li, Q]]
+
[[Category: Huang CH]]
-
[[Category: Oldfield, E]]
+
[[Category: Li Q]]
-
[[Category: Shang, N]]
+
[[Category: Oldfield E]]
-
[[Category: Drug discovery]]
+
[[Category: Shang N]]
-
[[Category: Human squalene synthase]]
+
-
[[Category: Isoprenoid]]
+
-
[[Category: Sq-109]]
+
-
[[Category: Transferase]]
+

Current revision

The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole

PDB ID 3wsa

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools