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3hr3

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==Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Hydrophobic Modifications Better than DNA==
==Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Hydrophobic Modifications Better than DNA==
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<StructureSection load='3hr3' size='340' side='right' caption='[[3hr3]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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<StructureSection load='3hr3' size='340' side='right'caption='[[3hr3]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3hr3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HR3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HR3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3hr3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HR3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HR3 FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=US4:[(2R,3S,5R)-3-({[(2R,3S,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXYTETRAHYDROFURAN-2-YL]METHOXY}METHOXY)-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-2-YL]METHYL+DIHYDROGEN+PHOSPHATE'>US4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hr3 OCA], [http://pdbe.org/3hr3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hr3 RCSB], [http://www.ebi.ac.uk/pdbsum/3hr3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hr3 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=US4:[(2R,3S,5R)-3-({[(2R,3S,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXYTETRAHYDROFURAN-2-YL]METHOXY}METHOXY)-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-2-YL]METHYL+DIHYDROGEN+PHOSPHATE'>US4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hr3 OCA], [https://pdbe.org/3hr3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hr3 RCSB], [https://www.ebi.ac.uk/pdbsum/3hr3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hr3 ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Egli, M]]
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[[Category: Large Structures]]
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[[Category: Pallan, P S]]
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[[Category: Synthetic construct]]
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[[Category: Dna]]
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[[Category: Egli M]]
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[[Category: Formacetal-dna]]
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[[Category: Pallan PS]]
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[[Category: Rna]]
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[[Category: Rna hydration]]
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Current revision

Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Hydrophobic Modifications Better than DNA

PDB ID 3hr3

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