5mfx

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==Zika NS3 helicase:RNA complex==
==Zika NS3 helicase:RNA complex==
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<StructureSection load='5mfx' size='340' side='right' caption='[[5mfx]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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<StructureSection load='5mfx' size='340' side='right'caption='[[5mfx]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5mfx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MFX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MFX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5mfx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Zika_virus Zika virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MFX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MFX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.598&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mfx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mfx OCA], [http://pdbe.org/5mfx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mfx RCSB], [http://www.ebi.ac.uk/pdbsum/5mfx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mfx ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mfx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mfx OCA], [https://pdbe.org/5mfx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mfx RCSB], [https://www.ebi.ac.uk/pdbsum/5mfx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mfx ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A146CJH9_ZIKV A0A146CJH9_ZIKV] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859]
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==See Also==
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*[[Virus protease 3D structures|Virus protease 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Antson, A A]]
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[[Category: Large Structures]]
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[[Category: Chechik, M]]
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[[Category: Zika virus]]
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[[Category: Ge, M]]
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[[Category: Antson AA]]
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[[Category: Greive, S J]]
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[[Category: Chechik M]]
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[[Category: Jenkins, H T]]
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[[Category: Ge M]]
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[[Category: Helicase]]
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[[Category: Greive SJ]]
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[[Category: Hydrolase]]
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[[Category: Jenkins HT]]
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[[Category: Rna]]
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Current revision

Zika NS3 helicase:RNA complex

PDB ID 5mfx

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