We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

5u1u

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:18, 4 October 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist A740003==
==Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist A740003==
-
<StructureSection load='5u1u' size='340' side='right' caption='[[5u1u]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
+
<StructureSection load='5u1u' size='340' side='right'caption='[[5u1u]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5u1u]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U1U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U1U FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5u1u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ailuropoda_melanoleuca Ailuropoda melanoleuca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U1U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5U1U FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7S4:N-{(1R)-1-[N-CYANO-N-(QUINOLIN-5-YL)CARBAMIMIDAMIDO]-2,2-DIMETHYLPROPYL}-2-(3,4-DIMETHOXYPHENYL)ACETAMIDE'>7S4</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.604&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5u1l|5u1l]], [[5u1v|5u1v]], [[5u1w|5u1w]], [[5u1x|5u1x]], [[5u1y|5u1y]], [[5u2h|5u2h]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7S4:N-{(1R)-1-[N-CYANO-N-(QUINOLIN-5-YL)CARBAMIMIDAMIDO]-2,2-DIMETHYLPROPYL}-2-(3,4-DIMETHOXYPHENYL)ACETAMIDE'>7S4</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5u1u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u1u OCA], [http://pdbe.org/5u1u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u1u RCSB], [http://www.ebi.ac.uk/pdbsum/5u1u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u1u ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5u1u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u1u OCA], [https://pdbe.org/5u1u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5u1u RCSB], [https://www.ebi.ac.uk/pdbsum/5u1u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5u1u ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/G1M6C4_AILME G1M6C4_AILME]] Receptor for ATP that acts as a ligand-gated ion channel.[RuleBase:RU000681]
+
[https://www.uniprot.org/uniprot/G1M6C4_AILME G1M6C4_AILME] Receptor for ATP that acts as a ligand-gated ion channel.[RuleBase:RU000681]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 19:
</div>
</div>
<div class="pdbe-citations 5u1u" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5u1u" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Ion channels 3D structures|Ion channels 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Karasawa, A]]
+
[[Category: Ailuropoda melanoleuca]]
-
[[Category: Kawate, T]]
+
[[Category: Large Structures]]
-
[[Category: Membrane protein]]
+
[[Category: Karasawa A]]
-
[[Category: Membrane protein: atp-gated ion channel: allosteric antagonist bound: closed state]]
+
[[Category: Kawate T]]

Current revision

Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist A740003

PDB ID 5u1u

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5u1u"
Personal tools