5ucr

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==Crystal Structure of a Pantoate-beta-alanine Ligase from Neisseria gonorrhoeae with bound AMPPNP and Alanine==
==Crystal Structure of a Pantoate-beta-alanine Ligase from Neisseria gonorrhoeae with bound AMPPNP and Alanine==
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<StructureSection load='5ucr' size='340' side='right' caption='[[5ucr]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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<StructureSection load='5ucr' size='340' side='right'caption='[[5ucr]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ucr]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UCR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UCR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ucr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_gonorrhoeae_NCCP11945 Neisseria gonorrhoeae NCCP11945]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UCR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UCR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kwv|5kwv]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantoate--beta-alanine_ligase Pantoate--beta-alanine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.1 6.3.2.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ucr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ucr OCA], [https://pdbe.org/5ucr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ucr RCSB], [https://www.ebi.ac.uk/pdbsum/5ucr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ucr ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ucr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ucr OCA], [http://pdbe.org/5ucr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ucr RCSB], [http://www.ebi.ac.uk/pdbsum/5ucr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ucr ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/B4RKE7_NEIG2 B4RKE7_NEIG2]] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.[HAMAP-Rule:MF_00158][SAAS:SAAS00247587]
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[https://www.uniprot.org/uniprot/B4RKE7_NEIG2 B4RKE7_NEIG2] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.[HAMAP-Rule:MF_00158][SAAS:SAAS00247587]
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==See Also==
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*[[Pantothenate synthetase|Pantothenate synthetase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Pantoate--beta-alanine ligase]]
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[[Category: Large Structures]]
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[[Category: Neisseria gonorrhoeae NCCP11945]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
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[[Category: Amppnp]]
 
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[[Category: Ligase]]
 
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[[Category: Pantoate-beta-alanine_ligase]]
 
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[[Category: Ssgcid]]
 

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Crystal Structure of a Pantoate-beta-alanine Ligase from Neisseria gonorrhoeae with bound AMPPNP and Alanine

PDB ID 5ucr

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