1rqx

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[[Image:1rqx.gif|left|200px]]
 
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{{Structure
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==Crystal structure of ACC Deaminase complexed with Inhibitor==
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|PDB= 1rqx |SIZE=350|CAPTION= <scene name='initialview01'>1rqx</scene>, resolution 2.50&Aring;
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<StructureSection load='1rqx' size='340' side='right'caption='[[1rqx]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MLP:1-AMINOCYCLOPROPYLPHOSPHONATE'>MLP</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5&#39;-PHOSPHATE'>PLP</scene>
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<table><tr><td colspan='2'>[[1rqx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._ACP Pseudomonas sp. ACP]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RQX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RQX FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/1-aminocyclopropane-1-carboxylate_deaminase 1-aminocyclopropane-1-carboxylate deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.99.7 3.5.99.7] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLP:1-AMINOCYCLOPROPYLPHOSPHONATE'>MLP</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rqx OCA], [https://pdbe.org/1rqx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rqx RCSB], [https://www.ebi.ac.uk/pdbsum/1rqx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rqx ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rqx OCA], [http://www.ebi.ac.uk/pdbsum/1rqx PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1rqx RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/1A1D_PSEUD 1A1D_PSEUD]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rq/1rqx_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rqx ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of ACC Deaminase complexed with Inhibitor'''
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==See Also==
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*[[Deaminase 3D structures|Deaminase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1RQX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp. Pseudomonas sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RQX OCA].
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[[Category: Large Structures]]
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[[Category: Pseudomonas sp. ACP]]
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==Reference==
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[[Category: Kao CL]]
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Structural analysis of 1-aminocyclopropane-1-carboxylate deaminase: observation of an aminyl intermediate and identification of Tyr 294 as the active-site nucleophile., Karthikeyan S, Zhao Z, Kao CL, Zhou Q, Tao Z, Zhang H, Liu HW, Angew Chem Int Ed Engl. 2004 Jun 28;43(26):3425-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15221829 15221829]
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[[Category: Karthikeyan S]]
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[[Category: 1-aminocyclopropane-1-carboxylate deaminase]]
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[[Category: Liu HW]]
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[[Category: Pseudomonas sp.]]
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[[Category: Tao Z]]
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[[Category: Single protein]]
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[[Category: Zhang H]]
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[[Category: Kao, C L.]]
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[[Category: Zhao Z]]
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[[Category: Karthikeyan, S.]]
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[[Category: Zhou Q]]
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[[Category: Liu, H W.]]
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[[Category: Tao, Z.]]
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[[Category: Zhang, H.]]
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[[Category: Zhao, Z.]]
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[[Category: Zhou, Q.]]
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[[Category: accd]]
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[[Category: complex]]
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[[Category: crystal]]
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[[Category: inhibitor]]
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[[Category: plp]]
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[[Category: structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:31:50 2008''
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Current revision

Crystal structure of ACC Deaminase complexed with Inhibitor

PDB ID 1rqx

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