5ulh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "5ulh" [edit=sysop:move=sysop])
Current revision (14:27, 6 March 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 5ulh is ON HOLD
+
==Structure of RNF165 in complex with a UbcH5b~Ub conjugate==
 +
<StructureSection load='5ulh' size='340' side='right'caption='[[5ulh]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[5ulh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ULH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ULH FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ulh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ulh OCA], [https://pdbe.org/5ulh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ulh RCSB], [https://www.ebi.ac.uk/pdbsum/5ulh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ulh ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/UB2D2_HUMAN UB2D2_HUMAN] Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.<ref>PMID:10329681</ref> <ref>PMID:15280377</ref> <ref>PMID:18042044</ref> <ref>PMID:18703417</ref> <ref>PMID:18359941</ref> <ref>PMID:19854139</ref> <ref>PMID:20403326</ref> <ref>PMID:20061386</ref>
-
Authors: Middleton, A.J., Day, C.L., Wright, J.D.
+
==See Also==
-
 
+
*[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]]
-
Description: Structure of RNF165 in complex with a UbcH5b~Ub conjugate
+
*[[3D structures of ubiquitin|3D structures of ubiquitin]]
-
[[Category: Unreleased Structures]]
+
*[[3D structures of ubiquitin conjugating enzyme|3D structures of ubiquitin conjugating enzyme]]
-
[[Category: Wright, J.D]]
+
== References ==
-
[[Category: Day, C.L]]
+
<references/>
-
[[Category: Middleton, A.J]]
+
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Day CL]]
 +
[[Category: Middleton AJ]]
 +
[[Category: Wright JD]]

Current revision

Structure of RNF165 in complex with a UbcH5b~Ub conjugate

PDB ID 5ulh

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5ulh"
Personal tools