5x1d
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5x1d is ON HOLD Authors: Nitta, R., Tomabechi, Y., Aoki, M., Shirouzu, M. Description: Crystal Structure of T246A-N247A Human CRMP-2 Mutant [[Categ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of T246A-N247A Human CRMP-2 Mutant== | |
| - | + | <StructureSection load='5x1d' size='340' side='right'caption='[[5x1d]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5x1d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X1D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5X1D FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5x1d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x1d OCA], [https://pdbe.org/5x1d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5x1d RCSB], [https://www.ebi.ac.uk/pdbsum/5x1d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5x1d ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Nitta | + | == Function == |
| - | [[Category: Shirouzu | + | [https://www.uniprot.org/uniprot/DPYL2_HUMAN DPYL2_HUMAN] Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton (By similarity). Plays a role in neuron projection morphogenesis.<ref>PMID:11477421</ref> <ref>PMID:15466863</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Aoki M]] | ||
| + | [[Category: Nitta R]] | ||
| + | [[Category: Shirouzu M]] | ||
| + | [[Category: Tomabechi Y]] | ||
Current revision
Crystal Structure of T246A-N247A Human CRMP-2 Mutant
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