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1s96

From Proteopedia

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[[Image:1s96.gif|left|200px]]
 
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{{Structure
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==The 2.0 A X-ray structure of Guanylate Kinase from E.coli==
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|PDB= 1s96 |SIZE=350|CAPTION= <scene name='initialview01'>1s96</scene>, resolution 2.0&Aring;
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<StructureSection load='1s96' size='340' side='right'caption='[[1s96]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>
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<table><tr><td colspan='2'>[[1s96]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S96 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Guanylate_kinase Guanylate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.8 2.7.4.8] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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|GENE= GMK, SPOR, B3648, C4473, SF3688, S4081 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s96 OCA], [https://pdbe.org/1s96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s96 RCSB], [https://www.ebi.ac.uk/pdbsum/1s96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s96 ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s96 OCA], [http://www.ebi.ac.uk/pdbsum/1s96 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1s96 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/KGUA_ECOLI KGUA_ECOLI] Essential for recycling GMP and indirectly, cGMP.<ref>PMID:8390989</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s9/1s96_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s96 ConSurf].
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<div style="clear:both"></div>
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'''The 2.0 A X-ray structure of Guanylate Kinase from E.coli'''
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==See Also==
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*[[Guanylate kinase 3D structures|Guanylate kinase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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1S96 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S96 OCA].
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Guanylate kinase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Klock HE]]
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[[Category: Klock, H E.]]
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[[Category: Kreusch A]]
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[[Category: Kreusch, A.]]
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[[Category: Lesley SA]]
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[[Category: Lesley, S A.]]
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[[Category: McMullan D]]
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[[Category: McMullan, D.]]
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[[Category: Rodrigues K]]
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[[Category: Rodrigues, K.]]
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[[Category: Spraggon G]]
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[[Category: Spraggon, G.]]
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[[Category: Vincent J]]
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[[Category: Vincent, J.]]
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[[Category: dimer]]
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[[Category: e coli]]
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[[Category: guanylate kinase]]
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[[Category: sad]]
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[[Category: x-ray structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:38:57 2008''
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Current revision

The 2.0 A X-ray structure of Guanylate Kinase from E.coli

PDB ID 1s96

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