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Antibody 3D structures
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| - | + | '''Humanized mouse antibody (hmFab)''' is a modified mFab which resembles more hFab.<br /> | |
| + | '''Broadly neutralizing Fab''' and '''Neutralizing Fab''' are anti-HIV Fab.<br /> | ||
| + | '''Lama antibodies''' or '''nanobodies''' or '''camelid''' or '''VHH''' are natural single-domain antibodies containing just the heavy chain.<br /> | ||
| + | '''scFv''' is a single chain variable fragment in a fusion protein of the variable regions of the heavy and light chains of immunoglobulin. | ||
| + | ==3D structures of [[Antibody]]== | ||
| + | |||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | |||
| - | '''Humanized mouse antibody (hmFab)''' is a modified mFab which resembles more hFab.<br /> | ||
| - | '''Broadly neutralizing Fab''' and '''Neutralizing Fab''' are anti-HIV Fab. | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| + | |||
*Fab | *Fab | ||
| - | **[[7fab]], [[1mco]], [[3na9]], [[3lrs]], [[3mme]], [[3hi5]], [[1vge]], [[3nfs]], [[1ad0]], [[3w9d]], [[4nm4]], [[8fab]], [[1opg]], [[4fnl]], [[4fqh]], [[ | + | **[[7fab]], [[1mco]], [[3na9]], [[3lrs]], [[3mme]], [[3hi5]], [[1vge]], [[3nfs]], [[1ad0]], [[3w9d]], [[4nm4]], [[8fab]], [[1opg]], [[4fnl]], [[4fqh]], [[6n32]], [[1aqk]], [[2hff]], [[2agj]], [[3hc0]], [[3g6a]], [[3dgg]], [[3dif]], [[1b2w]], [[3eyo]], [[3eyq]], [[2aj3]], [[3fzu]], [[3aaz]], [[3gje]], [[5fhb]], [[5fha]], [[5f6i]], [[5f6h]], [[5drw]], [[5d6c]], [[4py7]], [[4ptt]], [[4ob5]], [[5szf]], [[5chn]], [[4lkc]], [[4hie]], [[4gxv]], [[6be2]], [[6be4]], [[6cbj]], [[6dcv]], [[6dwc]], [[6foe]], [[6ghg]], [[6hkg]], [[6ias]], [[7uen]], [[7uel]], [[7uem]], [[6obz]], [[6pzg]], [[6pzh]], [[6q19]], [[6q1a]], [[6q1e]], [[6q1g]], [[6q1j]], [[6q1k]], [[6qbc]], [[6qcu]], [[6u85]], [[6u9u]], [[6vi2]], [[6vrq]], [[6v4r]], [[6vpy]], [[6vtu]], [[6w5a]], [[6w5d]], [[6wiy]], [[6wj0]], [[6wla]], [[6xrj]], [[6z3k]], [[7aj6]], [[7arn]], [[7jkb]], [[7jz1]], [[7jz4]], [[7ke1]], [[7kfg]], [[7kgu]], [[7kx4]], [[7lud]], [[7lyv]], [[7lyw]], [[7m1c]], [[7mf7]], [[7mf8]], [[7mf9]], [[7mfa]], [[7n04]], [[7n07]], [[7oo2]], [[7ps3]], [[7qxc]], [[7qxd]], [[7qxe]], [[7re9]], [[7sen]], [[7tus]], [[7u04]], [[7u0k]], [[7vsu]], [[7vsw]], [[7y0g]] - hFab - human<br /> |
| - | **[[3naa]], [[3nab]], [[3nac]], [[3ncj]], [[3o2v]], [[3hc3]], [[3hc4]] - hFab (mutant)<br /> | + | **[[3naa]], [[3nab]], [[3nac]], [[3ncj]], [[3o2v]], [[3hc3]], [[3hc4]], [[6uum]], [[6y1k]], [[6y1l]], [[6y1m]], [[6y1n]], [[7mfb]], [[7s8g]] - hFab (mutant)<br /> |
| - | **[[ | + | **[[6b6z]], [[6dzn]], [[5vz1]], [[7rpt]] - hFab anti-ebola virus<br /> |
| + | **[[6mtx]], [[6mty]], [[6nis]] - hFab anti-zika virus<br /> | ||
| + | **[[6ws6]] - hFab anti-sarbecovirus<br /> | ||
| + | **[[6phg]], [[6phh]] - hFab anti-malaria<br /> | ||
| + | **[[6dl8]] - hFab anti-influenza<br /> | ||
| + | **[[7kba]] - hFab anti-HCMV<br /> | ||
| + | **[[3i75]], [[1f4w]], [[1aif]], [[1ghf]], [[2z91]], [[1ind]], [[3bkc]], [[3bkm]], [[1iy0]], [[3pp3]], [[3pp4]], [[3okm]], [[2hkh]], [[1ay1]], [[1nbv]], [[1qbm]], [[1bbd]], [[1dsf]], [[1gpo]], [[1mnu]], [[1igf]], [[1for]], [[1k6q]], [[1bz7]], [[1dqd]], [[2ipt]], [[2iq9]], [[2iqa]], [[2w60]], [[2w9d]], [[3iu4]], [[1q9k]], [[1q9l]], [[1q9o]], [[2z4q]], [[1cl7]], [[1cr9]], [[1r24]], [[1gig]], [[1uyw]], [[1cgs]], [[2cgr]], [[1q0x]], [[1ibg]], [[3eo0]], [[2op4]], [[2q76]], [[2ojz]], [[2g60]], [[2dbl]], [[1dbj]], [[1dbk]], [[1dbm]], [[1dba]], [[1mrc]], [[2gcy]], [[1flr]], [[1uz6]], [[1rfd]], [[1t2q]], [[1ggb]], [[1ggc]], [[1bm3]], [[2eh7]], [[2fat]], [[3cfc]], [[1fl3]], [[3cfe]], [[4j1u]], [[4gq9]], [[3qg7]], [[3rvt]], [[3s62]], [[4gay]], [[5mx3]], [[5l88]], [[5i66]], [[5cma]], [[5az2]], [[4z0b]], [[4qth]], [[5vzr]], [[5lgh]], [[5l9d]], [[5l7x]], [[4lci]], [[4k23]], [[6hgu]], [[6ks2]], [[6p79]], [[6qnk]], [[6shg]], [[6ug7]], [[6ug8]], [[6uga]], [[6ugd]], [[6vl8]], [[6vl9]], [[6w4v]], [[6x5e]], [[6xuk]], [[6z7x]], [[7bg1]], [[7c95]], [[7f2s]], [[7fgk]], [[7nx2]], [[7sd2]], [[7t0f]], [[7t0g]], [[7t0h]], [[7t0k]], [[7t0i]], [[7t0j]], [[7te4]], [[7tuh]], [[7v3q]] - mFab – mouse<br /> | ||
**[[3eot]], [[2d03]], [[3esv]], [[3et9]] – mFab (mutant)<br /> | **[[3eot]], [[2d03]], [[3esv]], [[3et9]] – mFab (mutant)<br /> | ||
**[[3iy2]], [[3iy3]], [[3iy4]], [[3iy5]], [[3iy6]], [[3iy7]] - mFab – Cryo EM<br /> | **[[3iy2]], [[3iy3]], [[3iy4]], [[3iy5]], [[3iy6]], [[3iy7]] - mFab – Cryo EM<br /> | ||
| - | **[[1jpt]], [[3mxv]], [[2o5x]], [[1ucb]], [[1bbj]], [[1t04]], [[2fgw]], [[1fvd]], [[1fve]] - hmFab <br /> | + | **[[1jpt]], [[3mxv]], [[2o5x]], [[1ucb]], [[1bbj]], [[1t04]], [[2fgw]], [[1fvd]], [[1fve]], [[4kuz]], [[6l8t]], [[6w4w]] - hmFab <br /> |
**[[1cqk]] – mFab MAK33 CH3 domain<br /> | **[[1cqk]] – mFab MAK33 CH3 domain<br /> | ||
| + | **[[6a0x]] - mFab anti-influenza virus<br /> | ||
| + | **[[6h3h]] - mFab anti-fullerene<br /> | ||
| + | **[[6pyc]] - mFab anti-kappa<br /> | ||
| + | **[[6idh]], [[6kdh]] - mFab anti-photoproduct<br /> | ||
| + | **[[6qu9]] - mFab anti-antitrypsin<br /> | ||
**[[3mj8]], [[3r06]] – AhFab – Armenian hamster<br /> | **[[3mj8]], [[3r06]] – AhFab – Armenian hamster<br /> | ||
**[[3iy1]], [[1zan]] – raFab – rat<br /> | **[[3iy1]], [[1zan]] – raFab – rat<br /> | ||
| - | **[[4k3e]], [[4k3d]] | + | **[[4k3e]], [[4k3d]], [[6oo0]], [[6qn7]], [[6qn8]], [[6qn9]], [[6qna]] – bFab – bovine<br /> |
| - | + | **[[4b41]], [[4m3j]], [[7bnp]], [[7bnw]], [[7np9]], [[7phs]] – LgFab – ''Lama glama''<br /> | |
| - | **[[ | + | **[[6cjk]], [[7d9z]] – rFab - rabbit<br /> |
| - | + | **[[6df0]], [[6dez]] - syFab anti-phosphotyrosine - synthetic<br /> | |
| - | **[[ | + | |
| - | *Anti-HIV Fab | + | *Anti-HIV Fab or broadly neutralizing Fab |
| - | **[[1rz7]], [[1rz8]], [[1rzf]], [[1rzg]], [[1rzi]], [[3mlj]], [[3mug | + | **[[1rz7]], [[1rz8]], [[1rzf]], [[1rzg]], [[1rzi]], [[3mlj]], [[3mug]], [[3qeh]], [[3ttn]], [[rpi]], [[3tnm]], [[4fz8]], [[4f58]], [[4f57]], [[4f5a]], [[5iie]], [[5dt1]], [[5cey]], [[5cex]], [[5cck]], [[5bzw]], [[5bzd]], [[4rqq]], [[5uy3]], [[4qf1]], [[6avn]], [[6b3d]], [[6bla]], [[6cxl]], [[6mtr]], [[6mts]], [[6o3d]], [[6o3k]], [[6uul]], [[6vu2]], [[6wor]], [[6wos]], [[7l77]], [[7l79]], [[7rdj]], [[7rdk]], [[7rdl]], [[7rdm]], [[7u0b]], [[7u0c]], [[7uce]] - hFab <br /> |
**[[3nz8]], [[3o6k]], [[3ntc]], [[3qeg]] – mFab <br /> | **[[3nz8]], [[3o6k]], [[3ntc]], [[3qeg]] – mFab <br /> | ||
| - | **[[5kg9]] – hmFab | + | **[[5kg9]] – hmFab <br /> |
| - | **[[5dd6]], [[5dd5]], [[5dd3]], [[5dd1]], [[4rfe]], [[4q2z]] – rmFab – rhesus macaque <br /> | + | **[[5dd6]], [[5dd5]], [[5dd3]], [[5dd1]], [[4rfe]], [[4q2z]], [[5t4z]], [[6u3z]], [[6u6m]], [[6u6o]], [[6vor]], [[6vsr]], [[7ryu]], [[7ryv]] – rmFab – rhesus macaque <br /> |
| + | **[[7l6m]] – rmFab – Cryo EM <br /> | ||
| + | **[[7ra7]] – rFab <br /> | ||
| + | **[[3juy]], [[4ut7]] – hscFv anti-HIV<br /> | ||
| + | **[[3r0m]] – LgVHH anti-HIV<br /> | ||
| + | **[[2xxc]] – ViVHH anti-HIV - vicugna<br /> | ||
| - | *Fab: small molecule complex | + | *Anti-SARS-CoV-2 Fab |
| + | |||
| + | **[[6nb8]], [[6w7y]], [[6xca]], [[7dpm]], [[7jmx]], [[7k8n]], [[7k8o]], [[7k8p]], [[7k8q]], [[7k8r]], [[7kn3]], [[7kza]], [[7kzc]], [[7lk9]], [[7lka]], [[7n3e]], [[7n3f]], [[7n3g]], [[7n3h]], [[7sn1]], [[7wpv]], [[7zf6]], [[7zff]] - hFab anti-SARS-CoV-2<br /> | ||
| + | **[[6c6z]], [[4xak]], [[6w41]], [[6xc2]], [[6xc3]], [[6xc4]], [[6xc7]], [[6xkp]], [[6xkq]], [[6yla]], [[6zer]], [[6zlr]], [[7b3o]], [[7beh]], [[7bei]], [[7bej]], [[7bek]], [[7bel]], [[7bem]], [[7ben]], [[7beo]], [[7bep]], [[7bnv]], [[7bwj]], [[7bz5]], [[7c01]], [[7cah]], [[7cdi]], [[7cdj]], [[7ch4]], [[7ch5]], [[7chb]], [[7chc]], [[7che]], [[7chf]], [[7cho]], [[7chp]], [[7chs]], [[7cjf]], [[7cm4]], [[7djz]], [[7dk0]], [[7dk2]], [[7e3o]], [[7e5o]], [[7e5y]], [[7e7x]], [[7e7y]], [[7e86]], [[7e88]], [[7e8m]], [[7ejy]], [[7ejz]], [[7f6y]], [[7f7e]], [[7f7h]], [[7fcp]], [[7fcq]], [[7fjc]], [[7jjs]], [[7jmo]], [[7jmp]], [[7jmw]], [[7jn5]], [[7jx3]], [[7k8m]], [[7k9z]], [[7kfv]], [[7kfw]], [[7kfx]], [[7kfy]], [[7klg]], [[7klh]], [[7kmg]], [[7kmh]], [[7kmi]], [[7kn4]], [[7kzb]], [[7l0n]], [[7l2c]], [[7l5b]], [[7l7d]], [[7l7e]], [[7lm8]], [[7lm9]], [[7lop]], [[7lq7]], [[7ly3]], [[7m3i]], [[7m6d]], [[7mf1]], [[7mmo]], [[7msq]], [[7mzf]], [[7mzg]], [[7mzh]], [[7mzi]], [[7mzj]], [[7mzk]], [[7mzl]], [[7mzm]], [[7mzn]], [[7n3i]], [[7neg]], [[7neh]], [[7np1]], [[7nx6]], [[7nx7]], [[7nx8]], [[7nx9]], [[7nxa]], [[7nxb]], [[7or9]], [[7ora]], [[7orb]], [[7pry]], [[7prz]], [[7pqy]], [[7pqz]], [[7pr0]], [[7ps0]], [[7ps1]], [[7ps2]], [[7ps4]], [[7ps5]], [[7ps6]], [[7ps7]], [[7q0g]], [[7q0h]], [[7q0i]], [[7qez]], [[7qf0]], [[7qnw]], [[7qnx]], [[7qny]], [[7r6w]], [[7r6x]], [[7r8l]], [[7rku]], [[7rnj]], [[7s0b]], [[7s4s]], [[7s5p]], [[7s5q]], [[7s5r]], [[7sd5]], [[7si2]], [[7t7b]], [[7tcq]], [[7te1]], [[7tf1]], [[7tf4]], [[7tn0]], [[7tow]], [[7ttm]], [[7ttx]], [[7tty]], [[7u2d]], [[7u2e]], [[7urq]], [[7urs]], [[7vyr]], [[7wbz]], [[7wph]], [[7x7o]], [[7x9e]], [[7zf3]], [[7zf4]], [[7zf5]], [[7zf8]], [[7zf9]], [[7zfa]], [[7zfc]], [[7zfd]], [[7zfe]], [[8d36]], [[8d6z]], [[8dao]], [[8dcc]] - hFab + SARS-CoV-2 spike protein <br /> | ||
| + | **[[6nb6]], [[6nb7]], [[6wps]], [[6wpt]], [[6xcm]], [[6xcn]], [[6xdg]], [[6xey]], [[6yor]], [[6zdh]], [[6zdg]], [[6zfo]], [[7a5r]], [[7a5s]], [[7akd]], [[7akj]], [[7byr]], [[7bwj]], [[7c2l]], [[7cac]], [[7cai]], [[7cak]], [[7chh]], [[7cwl]], [[7cwm]], [[7cwn]], [[7cwo]], [[7cws]], [[7cwu]], [[7cyh]], [[7cyp]], [[7czq]], [[7czr]], [[7czs]], [[7czt]], [[7czu]], [[7czv]], [[7czw]], [[7czp]], [[7czx]], [[7d00]], [[7d03]], [[7d0b]], [[7d0c]], [[7d0d]], [[7d4g]], [[7dx4]], [[7dzx]], [[7dzy]], [[7e23]], [[7e39]], [[7e3b]], [[7e3c]], [[7e3k]], [[7e3l]], [[7e5r]], [[7e5s]], [[7e8c]], [[7e8f]], [[7e9n]], [[7e9o]], [[7e9p]], [[7e9q]], [[7eh5]], [[7ej4]], [[7ej5]], [[7ek0]], [[7enf]], [[7eng]], [[7epx]], [[7ey0]], [[7ey4]], [[7ey5]], [[7eya]], [[7ezv]], [[7f46]], [[7f62]], [[7f63]], [[7f6z]], [[7fae]], [[7faf]], [[7fjn]], [[7fjo]], [[7jv2]], [[7jv4]], [[7jv6]], [[7jva]], [[7jvc]], [[7jw0]], [[7k43]], [[7k45]], [[7k4n]], [[7k8s]], [[7k8t]], [[7k8u]], [[7k8v]], [[7k8w]], [[7k8x]], [[7k8y]], [[7k8x]], [[7k8y]], [[7k8z]], [[7k90]], [[7kmk]], [[7kml]], [[7kqb]], [[7kqe]], [[7ks9]], [[7kxj]], [[7kxk]], [[7l02]], [[7l06]], [[7l09]], [[7l2d]], [[7l2e]], [[7l2f]], [[7l3n]], [[7l56]], [[7l57]], [[7l58]], [[7laa]], [[7lab]], [[7ld1]], [[7lcn]], [[7ljr]], [[7lm8]], [[7lqv]], [[7lqw]], [[7lrs]], [[7lrt]], [[7ls9]], [[7lss]], [[7lxw]], [[7lxx]], [[7lxy]], [[7lxz]], [[7ly0]], [[7ly2]], [[7m42]], [[7m6e]], [[7m6f]], [[7m6g]], [[7m6h]], [[7m6i]], [[7m71]], [[7m7b]], [[7m8j]], [[7m8k]], [[7mkm]], [[7mlz]], [[7mm0]], [[7mw2]], [[7mw3]], [[7mw4]], [[7mw5]], [[7mw6]], [[7mxp]], [[7n5h]], [[7n62]], [[7n64]], [[7n8h]], [[7n8i]], [[7nd3]], [[7nd4]], [[7nd5]], [[7nd6]], [[7nd7]], [[7nd8]], [[7nd9]], [[7nda]], [[7ndb]], [[7ndc]], [[7ndd]], [[7ntc]], [[7p40]], [[7phg]], [[7pnm]], [[7pnq]], [[7po5]], [[7q0a]], [[7q6f]], [[7q9g]], [[7q9i]], [[7q9j]], [[7q9k]], [[7q9m]], [[7q9p]], [[7r40]], [[7r7n]], [[7r8m]], [[7r8n]], [[7r8o]], [[7ra8]], [[7ral]], [[7rb7]], [[7rbu]], [[7rkv]], [[7rq6]], [[7rr0]], [[7rw2]], [[7s0c]], [[7s0d]], [[7s0e]], [[7s6j]], [[7sb3]], [[7sb4]], [[7sbv]], [[7sbw]], [[7sbx]], [[7sby]], [[7sc1]], [[7sg4]], [[7sn2]], [[7sn3]], [[7so9]], [[7soa]], [[7sob]], [[7soc]], [[7sod]], [[7soe]], [[7sof]], [[7swn]], [[7swo]], [[7swp]], [[7t01]], [[7tas]], [[7tat]], [[7tb8]], [[7tbf]], [[7tc9]], [[7tca]], [[7tcc]], [[7the]], [[7tht]], [[7tly]], [[7tlz]], [[7tm0]], [[7u0d]], [[7uap]], [[7uaq]], [[7uar]], [[7upw]], [[7upx]], [[7upy]], [[7v23]], [[7v24]], [[7v26]], [[7v2a]], [[7v3l]], [[7we7]], [[7we8]], [[7we9]], [[7wea]], [[7web]], [[7wec]], [[7wed]], [[7wee]], [[7wef]], [[7whz]], [[7wi0]], [[7wjy]], [[7wjz]], [[7wk0]], [[7wk8]], [[7wlc]], [[7wly]], [[7wlz]], [[7wm0]], [[7wo4]], [[7wo5]], [[7wo7]], [[7woa]], [[7wob]], [[7woc]], [[7wog]], [[7won]], [[7wp0]], [[7wp1]], [[7wp2]], [[7wp5]], [[7wr8]], [[7wrl]], [[7wro]], [[7wrz]], [[7ws0]], [[7ws1]], [[7ws2]], [[7ws3]], [[7ws4]], [[7ws5]], [[7ws6]], [[7ws7]], [[7wuh]], [[7wwl]], [[7wwm]], [[7x08]], [[7x6a]], [[7xco]], [[7xck]], [[7xh8]], [[7xic]], [[7yad]], [[7zbu]], [[7zr7]], [[7zr8]], [[7zr9]], [[7zrc]], [[8dad]], [[8dlr]], [[8dls]], [[8dlt]], [[8dlw]], [[8dlx]], [[8dt3]] - hFab + SARS-CoV-2 spike protein – Cryo EM<br /> | ||
| + | **[[7sjs]] - hFab + SARS-CoV-2 spike protein peptide<br /> | ||
| + | **[[6yz7]], [[6z2m]], [[6zcz]], [[6zh9]], [[7fg2]], [[7fg3]], [[7kn6]], [[7kn7]], [[7raq]], [[7zfb]], [[7zxu]], [[8cwv]] - hFab + ViVHH + SARS-CoV-2 spike protein<br /> | ||
| + | **[[7xod]], [[8cwv]] - hFab + ViVHH + SARS-CoV-2 spike protein<br | ||
| + | **[[7n3c]], [[7n3d]], [[7str]], [[7sts]], [[7sue]] - hFab + SARS nucleoprotein<br /> | ||
| + | **[[7xcp]] - hFab + SARS-CoV-2 spike protein + ACE2 – Cryo EM<br /> | ||
| + | **[[8dfs]] - hFab + SARS-CoV-2 spike protein + ACE2<br /> | ||
| + | **[[7vnc]], [[7vnd]], [[7vne]], [[7whi]], [[7whj]], [[7whk]] - hVHH + SARS-CoV-2 spike protein – Cryo EM<br /> | ||
| + | **[[7wpd]], [[7wpe]], [[7wpf]] - mrFab + ViVHH + SARS-CoV-2 spike protein – Cryo EM<br /> | ||
| + | **[[7tp3]], [[7tp4]], [[7wue]] - mrFab + SARS-CoV-2 spike protein <br /> | ||
| + | **[[7k9h]], [[7k9i]], [[7k9j]], [[7k9k]], [[7mkl]], [[7wk6]], [[7wka]], [[7wrv]], [[7x7t]], [[7x7u]], [[7x7v]] - mFab + SARS-CoV-2 spike protein – Cryo EM<br /> | ||
| + | **[[7f0x]], [[7f12]], [[7f15]], [[7s3n]] - mFab + SARS-CoV-2 spike protein <br /> | ||
| + | **[[7m53]] - mFab + SARS-CoV-2 spike protein peptide<br /> | ||
| + | **[[7my2]], [[7my3]] – mVHH anti-SARS + SARS-CoV-2 spike protein <br /> | ||
| + | **[[7mjj]], [[7mjk]] - syFab + SARS-CoV-2 spike protein – Cryo EM<br /> | ||
| + | **[[7kkj]] – syVHH anti-SARS<br /> | ||
| + | **[[6waq]], [[6z43]], [[8cwu]] – LgVHH anti-SARS + spike protein<br /> | ||
| + | **[[7on5]] – ViVHH anti-SARS <br /> | ||
| + | **[[7f5g]], [[7f5h]], [[7kn5]], [[7ldj]], [[7olz]] – ViVHH anti-SARS + spike protein <br /> | ||
| + | **[[6zxn]] – ViVHH anti-SARS + spike protein – Cryo EM<br /> | ||
| + | **[[7c8v]], [[7c8w]], [[7can]], [[7d2z]], [[7d30]], [[7kgj]], [[7kgk]], [[7klw]], [[7mfu]] – syVHH + SARS-CoV-2 spike protein<br/> | ||
| + | **[[7a25]], [[7a29]], [[7kkk]], [[7kkl]], [[7mjl]], [[7n0g]], [[7mjh]], [[7n0h]] – syVHH + SARS-CoV-2 spike protein – Cryo EM<br/> | ||
| + | **[[7cyv]], [[7deo]], [[7det]], [[7deu]], [[7vmu]], [[8dce]] – hscFv + SARS spike protein<br /> | ||
| + | **[[7t3m]] - EcscFv + SARS-CoV spike protein – Cryo EM<br /> | ||
| + | **[[7b14]], [[7b17]], [[7b18]], [[7jvb]] - LgVHH + SARS spike glycoprotein <br /> | ||
| + | **[[7ksg]] - LgVHH + SARS spike glycoprotein – Cryo EM<br /> | ||
| + | **[[7r98]]- LgVHH + SARS nucleoprotein – Cryo EM<br /> | ||
| + | |||
| + | *Anti-MERS-CoV Fab | ||
| + | |||
| + | **[[6nb5]] - hFab anti-MERS-CoV<br /> | ||
| + | **[[6pxg]] - mFab anti-MERS-CoV<br /> | ||
| + | **[[7coe]] - hFab + MERS-CoV spike protein <br /> | ||
| + | **[[6nb3]], [[6nb4]], [[7v5k]], [[7v6n]] - hFab + MERS-CoV spike protein – Cryo EM<br /> | ||
| + | **[[6pxh]], [[6pz8]], [[7s3m]] - mFab anti-MERS-CoV + MERS-CoV protein<br /> | ||
| + | **[[6j11]] - mscFv + MERS-CoV spike protein<br /> | ||
| + | **[[6war]] - LgVHH + MERS-CoV spike protein<br /> | ||
| + | |||
| + | *Anti-hepatitis Fab | ||
| + | |||
| + | **[[6mwn]] – hFab + hepatitis A virus RNA<br /> | ||
| + | **[[4hs8]], [[5kzp]], [[7lki]] – hFab + hepatitis C virus peptide <br /> | ||
| + | **[[6bkb]], [[6bkc]], [[6bkd]], [[6mej]], [[6meh]], [[6mei]], [[6mek]], [[6u8d]], [[6u8k]], [[6uyf]], [[6urh]], [[6uyd]], [[6uyg]], [[6uym]], [[6wo3]], [[6wo4]], [[6woq]] - hFab anti-hepatitis C virus + glycoprotein<br /> | ||
| + | **[[7kql]] - hFab anti-hepatitis C virus + Hepatitis A cellular receptor<br /> | ||
| + | **[[7jtf]], [[7jtg]] - rmFab + hepatitis C envelope protein<br /> | ||
| + | **[[4why]], [[4wht]] - raFab + hepatitis C peptide<br /> | ||
| + | **[[5npi]], [[5npj]] – mscFv + hepatitis C peptide<br /> | ||
| + | **[[6jhq]], [[6jhr]], [[6jhs]], [[6jht]] - mFab + hepatitis A proteins – Cryo EM<br /> | ||
| + | **[[6cwt]] – rFab + Hepatitis B capsid<br /> | ||
| + | **[[6cwd]] – rscFv + hepatitis B capsid<br /> | ||
| + | **[[5nph]], [[6bzu]], [[6bzv]], [[6bzw]], [[6bzy]] – mFab + hepatitis C virus peptide <br /> | ||
| + | |||
| + | *Human Fab: small molecule complex | ||
**[[3o2w]] - hFab 1e9 (mutant) + transition state analog<br /> | **[[3o2w]] - hFab 1e9 (mutant) + transition state analog<br /> | ||
| - | **[[3ra7]] – mFab + digoxigenin <br /> | ||
| - | **[[3okd]], [[3oke]], [[3okk]], [[3okl]], [[3okn]], [[3oko]], [[3hzk]], [[3hzm]], [[3hzv]], [[3hzy]], [[3pho]], [[3phq]], [[3hns]], [[3hnt]], [[3hnv]] - mFab + liposaccharide<br /> | ||
**[[3oau]] – hFab 2g12 (mutant) + mannose<br /> | **[[3oau]] – hFab 2g12 (mutant) + mannose<br /> | ||
| - | **[[4ptu]] – hFab + rhamnose<br /> | + | **[[4ptu]], [[4hih]] – hFab + rhamnose<br /> |
**[[1ikf]] – hFab R45 + cyclosporin<br /> | **[[1ikf]] – hFab R45 + cyclosporin<br /> | ||
| - | **[[3oay]], [[3oaz]], [[3ob0]], [[ | + | **[[3oay]], [[3oaz]], [[3ob0]], [[6msy]], [[6mub]], [[6mu3]], [[6mnf]] - hFab 2g12 + glycan<br /> |
| - | **[[ | + | **[[6n35]], [[6n2x]], [[5i8o]] - hFab + polysaccharide<br /> |
| + | **[[7dc7]] - hFab + ATP<br /> | ||
| + | **[[6bjz]] - hFab + fluorescent amino acid<br /> | ||
| + | **[[7kkh]] - hFab + piperazine derivative<br /> | ||
| + | **[[6o3u]] - hFab anti-HIV + PA<br /> | ||
| + | |||
| + | *Mouse Fab: small molecule complex | ||
| + | |||
| + | **[[3ra7]] – mFab + digoxigenin <br /> | ||
| + | **[[3okd]], [[3oke]], [[3okk]], [[3okl]], [[3okn]], [[3oko]], [[3hzk]], [[3hzm]], [[3hzv]], [[3hzy]], [[3pho]], [[3phq]], [[3hns]], [[3hnt]], [[3hnv]] - mFab + liposaccharide<br /> | ||
**[[1ine]], [[1ub5]], [[1ub6]] - mFab + hapten<br /> | **[[1ine]], [[1ub5]], [[1ub6]] - mFab + hapten<br /> | ||
**[[3ls4]] – mFab + tetrahydrocannabinol<br /> | **[[3ls4]] – mFab + tetrahydrocannabinol<br /> | ||
**[[1mfc]], [[1mfd]], [[1mfe]], [[4hgw]] – mFab + polysaccharide<br /> | **[[1mfc]], [[1mfd]], [[1mfe]], [[4hgw]] – mFab + polysaccharide<br /> | ||
| - | **[[1op3]], [[1op5]], [[5i8o]] - hFab + polysaccharide<br /> | ||
| - | **[[3eyv]] - hmFab 13G5 (mutant) + hapten<br /> | ||
**[[2ntf]] - mFab RS2-1G9 + lactone analog<br /> | **[[2ntf]] - mFab RS2-1G9 + lactone analog<br /> | ||
**[[1riu]], [[1riv]], [[1qyg]], [[1q72]] - mFab + cocaine derivative<br /> | **[[1riu]], [[1riv]], [[1qyg]], [[1q72]] - mFab + cocaine derivative<br /> | ||
| Line 59: | Line 138: | ||
**[[1igj]] - mFab 26-10 + digoxin<br /> | **[[1igj]] - mFab 26-10 + digoxin<br /> | ||
**[[4fab]] – mFab 4-4-20 + fluorescin<br /> | **[[4fab]] – mFab 4-4-20 + fluorescin<br /> | ||
| + | **[[7f35]] – mFab + gatifloxacin<br /> | ||
**[[1dl7]] - mFab MCPC603 + phosphocholine<br /> | **[[1dl7]] - mFab MCPC603 + phosphocholine<br /> | ||
**[[3cfb]], [[3cfd]], [[2g2r]] – mFab + stilbene hapten<br /> | **[[3cfb]], [[3cfd]], [[2g2r]] – mFab + stilbene hapten<br /> | ||
| - | **[[ | + | **[[4kze]], [[4kzd]], [[7szu]], [[7u0y]] – mFab + RNA <br /> |
| + | **[[6kdi]] - mFab anti-photoproduct + DNA<br /> | ||
| + | |||
| + | *Other Fab: small molecule complex | ||
| + | |||
| + | **[[2jb5]], [[2jb6]] - hmFab + hapten<br /> | ||
| + | **[[3eyv]] - hmFab 13G5 (mutant) + hapten<br /> | ||
| - | *Fab: peptide complex | + | *Mouse Fab: peptide complex |
**[[3e8u]] - mFab + BNP peptide<br /> | **[[3e8u]] - mFab + BNP peptide<br /> | ||
| Line 70: | Line 156: | ||
**[[3eys]], [[3eyu]] - mFab + amyloid-β-related peptide<br /> | **[[3eys]], [[3eyu]] - mFab + amyloid-β-related peptide<br /> | ||
**[[3ggw]] – mFab + carbohydrate-mimetic peptide<br /> | **[[3ggw]] – mFab + carbohydrate-mimetic peptide<br /> | ||
| - | **[[3cxd]], [[3dsf]] – mFab + osteopontin peptide<br /> | + | **[[3cxd]], [[3dsf]], [[5x5x]] – mFab + osteopontin peptide<br /> |
**[[2zpk]] – mFab + proteinase-activated receptor peptide<br /> | **[[2zpk]] – mFab + proteinase-activated receptor peptide<br /> | ||
| - | **[[3ifl]], [[3ifn]], [[3ifo]], [[3ifp | + | **[[3ifl]], [[3ifn]], [[3ifo]], [[3ifp]], [[7e6p]] - mFab + amyloid peptide<br /> |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
**[[2eh8]] - mFab + PRES1 peptide<br /> | **[[2eh8]] - mFab + PRES1 peptide<br /> | ||
**[[2brr]] – mFab + outer membrane protein peptide<br /> | **[[2brr]] – mFab + outer membrane protein peptide<br /> | ||
| - | **[[1xgy]] – mFab + rhodopsin peptide<br /> | + | **[[1xgy]], [[7doh]] – mFab + rhodopsin peptide<br /> |
**[[1pz5]] – mFab SYA/J6 + peptide<br /> | **[[1pz5]] – mFab SYA/J6 + peptide<br /> | ||
**[[1a3r]] – mFab + rhinovirus capsid peptide<br /> | **[[1a3r]] – mFab + rhinovirus capsid peptide<br /> | ||
**[[1cu4]] - mFab + prion protein peptide<br /> | **[[1cu4]] - mFab + prion protein peptide<br /> | ||
**[[1fpt]] – mFab + poliovirus peptide<br /> | **[[1fpt]] – mFab + poliovirus peptide<br /> | ||
| - | **[[1jp5]] – mFab + HIV-1 protease peptide<br /> | ||
**[[1mvu]] – mFab + glycoprotein <br /> | **[[1mvu]] – mFab + glycoprotein <br /> | ||
**[[2ap2]] – mFab + glycoprotein peptide + C-myc peptide<br /> | **[[2ap2]] – mFab + glycoprotein peptide + C-myc peptide<br /> | ||
| - | **[[2hh0]] – hFab/mFab + prion protein peptide<br /> | ||
**[[1frg]], [[1him]], [[1hin]], [[1ifh]] - mFab + hemagglutinin peptide<br /> | **[[1frg]], [[1him]], [[1hin]], [[1ifh]] - mFab + hemagglutinin peptide<br /> | ||
**[[1tet]] – mFab + cholera toxin peptide<br /> | **[[1tet]] – mFab + cholera toxin peptide<br /> | ||
**[[5epm]] – mFab + therapotoxin peptide<br /> | **[[5epm]] – mFab + therapotoxin peptide<br /> | ||
| - | **[[5eor]], [[5eoq]] – mFab + protein A27 peptide<br /> | ||
**[[1i8i]], [[1i8k]] – mFab + EGFR peptide<br /> | **[[1i8i]], [[1i8k]] – mFab + EGFR peptide<br /> | ||
| - | **[[1i8k]] – mFab + EGFR peptide<br /> | ||
| - | **[[1i8i]], [[1i8k]] – mFab + EGFR peptide<br /> | ||
| - | **[[1i8k]] – mFab + EGFR peptide<br /> | ||
**[[4gag]], [[4gaj]] – mFab + genome polyprotein peptide<br /> | **[[4gag]], [[4gaj]] – mFab + genome polyprotein peptide<br /> | ||
| + | **[[5mv4]], [[5mu0]] – mFab + collagen peptide <br /> | ||
| + | **[[6f7t]] – mFab + RNase peptide<br /> | ||
| + | **[[7njz]], [[7nw3]] – mFab + chemokine receptor peptide<br /> | ||
| + | **[[7v4w]], [[7v64]], [[7v7k]], [[7v8q]], [[7vac]], [[7vaz]] – mFab + mucin peptide<br /> | ||
| + | **[[7o2z]], [[7o30]], [[7o31]], [[7o33]] – mFab + PAS peptide<br /> | ||
| + | **[[7fgj]], [[7fgl]], [[7fgr]] - mFab + Tau peptide<br /> | ||
| + | |||
| + | *Human Fab: peptide complex | ||
| + | |||
| + | **[[3h0t]] - hFab + hepcidin peptide<br /> | ||
| + | **[[1sm3]] - hFab SM3 + peptide<br /> | ||
| + | **[[5ea0]] - hFab 7968 + complement factor peptide<br /> | ||
| + | **[[4z0x]], [[4xvj]] - hFab + HCV E2 peptide<br /> | ||
| + | **[[3eyf]], [[4hha]] – hFab + cytomegalovirus peptide<br /> | ||
| + | **[[2hfg]], [[2h9g]] – hFab + TNF receptor peptide<br /> | ||
| + | **[[3csy]], [[6n7j]], [[7rpu]] - hFab + Ebola envelope glycoprotein peptide<br /> | ||
| + | **[[6h06]], [[6h0e]], [[6gk7]], [[6gk8]], [[5zia]], [[5zv3]], [[6dcw]], [[7eyc]], [[7kqk]] - hFab + Tau peptide<br /> | ||
| + | **[[6bqb]], [[6ct7]], [[6kva]], [[6kvf]], [[6ldv]], [[6ldw]], [[6ldx]], [[7bxv]], [[7c94]], [[7y3j]] – hFab + peptide<br /> | ||
| + | **[[6e4y]], [[6e4z]], [[6mv5]] - hFab + PCSK9 peptide<br /> | ||
| + | **[[7jwq]] - hFab + IL-1b peptide<br /> | ||
| + | **[[7jwp]] - hFab + IL-18 peptide<br /> | ||
| + | **[[7sfx]] - hFab + CD99 peptide<br /> | ||
| + | **[[7um3]] - hFab + LAG3 peptide<br /> | ||
| + | **[[7rta]] - hFab + neuropeptide Y<br /> | ||
| + | **[[7k7r]] - hFab + EBNA1 peptide<br /> | ||
| + | **[[7rt9]] - hFab + YY peptide<br /> | ||
| + | **[[7s4g]] - hFab + Ly6G6D peptide<br /> | ||
| + | **[[7ow1]], [[7oxn]] - hFab + amyloid peptide<br /> | ||
| + | |||
| + | *Other Fab: peptide complex | ||
| + | |||
| + | **[[2hh0]] – hmFab + prion protein peptide<br /> | ||
**[[3bky]] – hmFab + CD20 peptide<br /> | **[[3bky]] – hmFab + CD20 peptide<br /> | ||
| - | **[[ | + | **[[5dmg]] – rFab + microtubule-associated protein peptide<br /> |
| - | **[[ | + | **[[6ldy]], [[6x1s]], [[6x1t]], [[6x1u]], [[6x1v]], [[6x1w]] – rFab + peptide<br /> |
**[[5dd0]] – rmFab + peptide<br /> | **[[5dd0]] – rmFab + peptide<br /> | ||
| + | **[[6df1]], [[6df2]] - syFab anti-phosphotyrosine + phosphotyrosine peptide<br /> | ||
*Anti-HIV Fab: peptide complex | *Anti-HIV Fab: peptide complex | ||
| - | **[[3egs]], [[3drt]], [[3drq]], [[3dro]], [[2fx7]], [[2fx8]], [[2fx9]], [[2cmr]], [[1tzg]], [[1tjg]], [[3mnw]], [[3moa]], [[3mob]], [[3mod]], [[1tjh]], [[1tji]], [[1u8h]], [[1u8i]], [[1u8j]], [[1u8k]], [[1u8l]], [[1u8m]], [[1u8n]], [[1u8o]], [[1u8p]], [[1u8q]], [[1u91]], [[1u92]], [[1u93]], [[1u95]], [[2f5b]], [[3go1]], [[5drz]], [[ | + | **[[3egs]], [[3drt]], [[3drq]], [[3dro]], [[2fx7]], [[2fx8]], [[2fx9]], [[2cmr]], [[1tzg]], [[1tjg]], [[3mnw]], [[3moa]], [[3mob]], [[3mod]], [[1tjh]], [[1tji]], [[1u8h]], [[1u8i]], [[1u8j]], [[1u8k]], [[1u8l]], [[1u8m]], [[1u8n]], [[1u8o]], [[1u8p]], [[1u8q]], [[1u91]], [[1u92]], [[1u93]], [[1u95]], [[2f5b]], [[3go1]], [[5drz]], [[6o42]] - hFab anti-HIV + gp41 peptide<br /> |
**[[3ghb]], [[3ghe]], [[3c2a]] - hFab anti-HIV + envelope glycoprotein peptide<br /> | **[[3ghb]], [[3ghe]], [[3c2a]] - hFab anti-HIV + envelope glycoprotein peptide<br /> | ||
| - | **[[3fn0]], [[2oqj]] - hFab + peptide<br /> | + | **[[3fn0]], [[2oqj]], [[6fy0]], [[6fy3]], [[6mtp]], [[6mtt]], [[6ncp]], [[6o3j]] - hFab anti-HIV + peptide<br /> |
| - | **[[2b0s]], [[2b1a]], [[2b1h]], [[3se8]], [[3se9]], [[4jkp]], [[4jpv]], [[4jb9]] - hFab anti-HIV + glycoprotein gp120 peptide<br /> | + | **[[2b0s]], [[2b1a]], [[2b1h]], [[3se8]], [[3se9]], [[4jkp]], [[4jpv]], [[4jb9]], [[6vbo]], [[6vbp]], [[6vbq]] - hFab anti-HIV + glycoprotein gp120 peptide<br /> |
**[[1nak]], [[2f58]], [[3f58]], [[1f58]], [[1acy]], [[1qnz]] - mFab anti-HIV + glycoprotein gp120 peptide<br /> | **[[1nak]], [[2f58]], [[3f58]], [[1f58]], [[1acy]], [[1qnz]] - mFab anti-HIV + glycoprotein gp120 peptide<br /> | ||
**[[1ai1]], [[1ggi]] – mFab anti-HIV + V3 peptide<br /> | **[[1ai1]], [[1ggi]] – mFab anti-HIV + V3 peptide<br /> | ||
**[[3o6l]], [[3o6m]] - mFab 11H6H1 anti-HIV + Tat peptide<br /> | **[[3o6l]], [[3o6m]] - mFab 11H6H1 anti-HIV + Tat peptide<br /> | ||
| - | **[[1svz]] - mFab anti-HIV + HIV-2 protease peptide<br /> | + | **[[1jp5]], [[1svz]] - mFab anti-HIV + HIV-2 protease peptide<br /> |
| + | **[[6p8d]], [[6p8n]], [[6pdr]], [[6pdu]], [[6ubi]], [[6uce]], [[6ucf]], [[6wwc]], [[6wx2]] – mFab + HIV-1 fusion peptide<br /> | ||
| + | **[[6mqc]], [[6mqe]], [[6mqm]], [[6mqr]], [[6mqs]], [[6n16]], [[6pds]], [[6pec]], [[6pef]] - rmFab + HIV fusion peptide<br /> | ||
| + | **[[6mnq]], [[6mnr]], [[6mns]] - rmFab anti-HIV + gp120 peptide<br /> | ||
| + | **[[6p60]], [[6p7h]] - Fab + HIV fusion peptide - platytthini<br /> | ||
| - | *Fab: protein complex | + | *Human Fab: protein complex |
| - | **[[3raj]] – mFab HB7 + CD38<br /> | ||
| - | **[[3o0r]] – mFab + nitric oxide reductase<br /> | ||
| - | **[[3mac]], [[3ma9]] – hFab anti-HIV 8062 + transmembrane glycoprotein<br /> | ||
| - | **[[4xak]] – hFab anti-HIV M336 + spike glycoprotein<br /> | ||
**[[3pnw]] – hFab + Tudor domain-containing protein 3<br /> | **[[3pnw]] – hFab + Tudor domain-containing protein 3<br /> | ||
**[[3h42]] - hFab LDLR + proprotein convertase subtilisin/kexin<br /> | **[[3h42]] - hFab LDLR + proprotein convertase subtilisin/kexin<br /> | ||
**[[3nh7]] – hFab ABD1556 + bone morphogenetic protein receptor<br /> | **[[3nh7]] – hFab ABD1556 + bone morphogenetic protein receptor<br /> | ||
| - | **[[3hi6]] – hFab | + | **[[3hi6]] – hFab + integrin<br /> |
| + | **[[6avq]], [[6avr]], [[6avu]], [[7usl]] – hFab + integrin – Cryo EM<br /> | ||
**[[2vxs]], [[5fhx]] - hFab + interleukin<br /> | **[[2vxs]], [[5fhx]] - hFab + interleukin<br /> | ||
**[[3b2u]], [[3b2v]] – hFab IMC-11F8 + EGFR<br /> | **[[3b2u]], [[3b2v]] – hFab IMC-11F8 + EGFR<br /> | ||
**[[2r0k]], [[2r0l]] – hFab + HGFA<br /> | **[[2r0k]], [[2r0l]] – hFab + HGFA<br /> | ||
| - | **[[ | + | **[[3be1]], [[3n85]], [[1n8z]], [[6att]] - hFab + ERBB-2<br /> |
| - | + | **[[7d85]] - hFab + ERB-3<br /> | |
**[[3kr3]] – hFab + IGF-II<br /> | **[[3kr3]] – hFab + IGF-II<br /> | ||
| + | **[[7o52]] – hFab + CD22<br /> | ||
| + | **[[6yio]], [[7f9w]] – hFab + CD25<br /> | ||
| + | **[[7sgm]] – hFab + CD40<br /> | ||
| + | **[[7myz]] – hFab + CD47<br /> | ||
| + | **[[7chy]], [[7chz]] - hFab + IL-1b <br /> | ||
| + | **[[6oel]] – hFab + IL-4R<br /> | ||
| + | **[[7dc8]] – hFab + IL-6R<br /> | ||
| + | **[[7rew]] – hFab + IL-13R<br /> | ||
| + | **[[6plh]] – hFab + IL-21R<br /> | ||
| + | **[[6u6u]] – hFab + IL-36R<br /> | ||
| + | **[[6ppg]], [[6wio]] - hFab + IL-17<br /> | ||
| + | **[[7wkx]] – hFab + IL-17A<br /> | ||
| + | **[[6hga]], [[6ppg]] – hFab + IL-17R<br /> | ||
**[[3g6d]] – hFab CNTO607 + IL-13<br /> | **[[3g6d]] – hFab CNTO607 + IL-13<br /> | ||
| - | **[[ | + | **[[3g6j]], [[7ue9]] – hFab + complement C3<br /> |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
**[[2wub]], [[3k2u]] – hFab 40 + hepatocyte growth factor activator<br /> | **[[2wub]], [[3k2u]] – hFab 40 + hepatocyte growth factor activator<br /> | ||
| + | **[[6iz9]] – hFab + hepatocyte growth factor<br /> | ||
| + | **[[6i04]] – hFab + hepatocyte growth factor receptor<br /> | ||
| + | **[[6ktr]] - hFab + fibroblast growth factor <br /> | ||
**[[3grw]] - hFab + fibroblast growth factor receptor<br /> | **[[3grw]] - hFab + fibroblast growth factor receptor<br /> | ||
| - | **[[3bdy]], [[2qr0]], [[2fjg]], [[2fjh]], [[1cz8]] | + | **[[6ba5]] - hFab + tyrosine protein kinase receptor<br /> |
| - | + | **[[3bdy]], [[2qr0]], [[2fjg]], [[2fjh]], [[1cz8]], [[5fv2]], [[5fv1]], [[6t9d]], [[7kez]], [[7kf0]], [[7kf1]] – hFab + VEGF<br /> | |
| - | + | ||
**[[1adq]] – hFab IGM + igG1 Fc<br /> | **[[1adq]] – hFab IGM + igG1 Fc<br /> | ||
| + | **[[6eyo]], [[7si0]] – hFab + igE<br /> | ||
**[[3dvg]], [[3dvn]] – hFab igG1 + ubiquitin<br /> | **[[3dvg]], [[3dvn]] – hFab igG1 + ubiquitin<br /> | ||
| - | **[[3bn9]] – hFab E2 + | + | **[[3bn9]], [[7sjn]], [[7sjo]] – hFab E2 + serine protease<br /> |
**[[2jix]] – hFab ABT-007 + erythropoietin receptor<br /> | **[[2jix]] – hFab ABT-007 + erythropoietin receptor<br /> | ||
| - | **[[1za3]] - hFab | + | **[[1za3]], [[6t3j]] - hFab + TNF receptor<br /> |
| + | **[[6ogx]], [[6okm]], [[6okn]] - hFab + TNFRSF4<br /> | ||
**[[3l95]] – hFab + NRR1<br /> | **[[3l95]] – hFab + NRR1<br /> | ||
**[[1uj3]], [[4dtg]] – hFab + tissue factor<br /> | **[[1uj3]], [[4dtg]] – hFab + tissue factor<br /> | ||
**[[3lev]] – hFab 2F5 + RNA polymerase sigma factor<br /> | **[[3lev]] – hFab 2F5 + RNA polymerase sigma factor<br /> | ||
| - | **[[3ru8]] – hFab | + | **[[3ru8]], [[6mto]], [[6mtq]], [[6s3d]] – hFab + scaffold <br /> |
**[[3skj]] – hFab + ephrin receptor<br /> | **[[3skj]] – hFab + ephrin receptor<br /> | ||
**[[3sob]] – hFab + LPR6<br /> | **[[3sob]] – hFab + LPR6<br /> | ||
| - | **[[5lcv]] – hFab + polyprotein<br /> | ||
| - | **[[5gzo]], [[5gzn]] – hFab + zika polyprotein<br /> | ||
| - | **[[5lbs]] – hFab + envelope protein<br /> | ||
| - | **[[4utb]], [[4uta]], [[4ut9]], [[4ut6]] – hFab anti-HIV + dengue envelope protein<br /> | ||
| - | **[[5hj3]], [[5fhc]] – hFab + ebola envelope protein<br /> | ||
**[[5kn5]] - hFab + protransforming growth factor alpha<br /> | **[[5kn5]] - hFab + protransforming growth factor alpha<br /> | ||
**[[5c8j]] – hFab + protein MJ0480<br /> | **[[5c8j]] – hFab + protein MJ0480<br /> | ||
**[[4zso]] – hFab + natural cytotoxicity triggering receptor<br /> | **[[4zso]] – hFab + natural cytotoxicity triggering receptor<br /> | ||
| - | **[[ | + | **[[4rrp]], [[6ayz]], [[6az2]] - hFab + ASF1 <br /> |
| - | + | ||
| - | + | ||
**[[4qci]] - hFab + platelet factor B<br /> | **[[4qci]] - hFab + platelet factor B<br /> | ||
| - | **[[4mxv]] - hFab + | + | **[[7ket]], [[7lcv]] - hFab + factor H BP<br /> |
| - | **[[ | + | **[[4mxv]] - hFab + lymphotoxin <br /> |
| - | **[[3vga]] – hFab + adenosine receptor | + | **[[7seg]] - hFab + CD16 <br /> |
| + | **[[6al5]] - hFab + CD19 <br /> | ||
| + | **[[5dmj]], [[5ihl]], [[6fax]], [[6pe8]], [[6pe9]] - hFab + CD40 <br /> | ||
| + | **[[6hxw]] - hFab + CD73 <br /> | ||
| + | **[[3vg9]], [[3vga]] – hFab + adenosine receptor<br /> | ||
**[[2qqk]], [[2qql]], [[2qqn]] – hFab + neuropilin<br /> | **[[2qqk]], [[2qql]], [[2qqn]] – hFab + neuropilin<br /> | ||
**[[2vyr]] – hFab + MDM4<br /> | **[[2vyr]] – hFab + MDM4<br /> | ||
| - | **[[4c2i]] – hFab + dengue virus envelope protein<br /> | + | **[[6b0h]], [[6b0g]], [[6b0e]], [[6b0a]], [[6b08]], [[6azz]] - hFab + PFS25 <br /> |
| - | **[[4dag]] – hFab + metapneumovirus glycoprotein F0<br /> | + | **[[6hhc]], [[6r8x]], [[7ahu]], [[7k66]], [[7kbt]] - hFab + coagulation factor <br /> |
| - | **[[ | + | **[[5oca]], [[6u36]], [[6u38]] - hFab + PCSK9 <br /> |
| + | **[[5n88]] - hFab + SFRS1-interacting protein <br /> | ||
| + | **[[5bk1]], [[5bjz]] - hFab + maltose-binding protein <br /> | ||
| + | **[[4hj0]], [[6dkj]] - hFab + GIPR <br /> | ||
| + | **[[4g80]], [[4g7y]], [[4g7v]] - hFab + VSP <br /> | ||
| + | **[[6cyf]] – hFab + secretion system protein<br /> | ||
| + | **[[6cw3]] – hFab + histone acetyltransferase <br /> | ||
| + | **[[6m58]] – hFab + serum albumin<br /> | ||
| + | **[[6mvl]] – hFab + VISTA<br /> | ||
| + | **[[6nmr]], [[6nms]], [[6nmt]], [[6nmu]], [[6nmv]], [[7kpg]] – hFab + SIRP-alpha<br /> | ||
| + | **[[6o39]] – hFab + frizzled-5<br /> | ||
| + | **[[6o3a]], [[6o3b]] – hFab + frizzled-7<br /> | ||
| + | **[[6phb]], [[6phc]], [[6phd]], [[6phf]] – hFab + PFS25<br /> | ||
| + | **[[6r0x]] – hFab + G6B<br /> | ||
| + | **[[6o41]], [[6u8c]] – hFab + protein G<br /> | ||
| + | **[[6xxv]] – hFab + S2_1.2<br /> | ||
| + | **[[6c9u]], [[6mlk]] – hFab + DEBS<br /> | ||
| + | **[[7m7e]], [[7m7f]], [[7m7g]], [[7m7h]], [[7m7i]], [[7m7j]], [[7s6c]], [[7s6d]] – hFab + DEBS – Cryo EM<br /> | ||
| + | **[[6o9h]] – hFab + ECD<br /> | ||
| + | **[[7dm1]], [[7dm2]] – hFab + PstS-1<br /> | ||
| + | **[[6vgr]] - hFab + dipeptidase<br /> | ||
| + | **[[6vvu]] - hFab + tryptase<br /> | ||
| + | **[[6j14]], [[6j15]], [[7c88]], [[7e9b]], [[7vux]], [[7wsl]] - hFab + PD-1<br /> | ||
| + | **[[6vc9]], [[6vca]] - hFab + nucleotidase<br /> | ||
| + | **[[6i3z]] - hFab anti-antitrypsin + antitrypsin<br /> | ||
| + | **[[6xy2]], [[7elx]], [[7su0]], [[7su1]] – hFab + CTLA<br /> | ||
| + | **[[6xmi]] – hFab + terminase<br /> | ||
| + | **[[6cbv]] – hFab + BRIL<br /> | ||
| + | **[[7khf]] – hFab + rifin<br /> | ||
| + | **[[6y9b]] – hFab + STEAP1<br /> | ||
| + | **[[6fn4]] – hFab + ABCB<br /> | ||
| + | **[[7neq]], [[7nfd]] – hFab + ABCG2 – Cryo EM<br /> | ||
| + | **[[7nez]] – hFab + ABCG2 + drug – Cryo EM<br /> | ||
| + | **[[6bdz]] – hFab + ADAM-10<br /> | ||
| + | **[[7c61]] – hFab + HT1B<br /> | ||
| + | **[[6m3b]], [[6m3c]] – hFab + vitamin K-dependent protein<br /> | ||
| + | **[[7mxl]] - hFab + pollen allergen – Cryo EM<br /> | ||
| + | **[[7ssv]] - hFab + Kv1.3 – Cryo EM<br /> | ||
| + | **[[7phu]] – hFab + RH5<br /> | ||
| + | **[[7ce2]], [[7oh0]], [[7oh1]] – hFab + tetanus toxin<br /> | ||
| + | **[[7vyt]] – hFab + TIGIT<br /> | ||
| + | **[[7bbj]] – hFab + nucleotidase<br /> | ||
| + | **[[7lj4]], [[7lj5]], [[7lja]], [[7ljb]] – hFab + TRAAK <br /> | ||
| + | **[[7fci]], [[7vad]] – hFab + NTCP – Cryo EM<br /> | ||
| + | **[[7lk4]] – hFab + Bcl-2<br /> | ||
| + | **[[7daa]] – hFab + basigin<br /> | ||
| + | **[[7mnl]], [[7mnm]], [[7mnn]], [[7mno]] – hFab + NUP358/RanBP<br /> | ||
| + | **[[7ahv]] – hFab + FIXa<br /> | ||
| + | **[[7cj2]] – hFab + YAK-40<br /> | ||
| + | **[[7e72]] – hFab + angiopoietin receptor<br /> | ||
| + | **[[7rco]] – hFab + TGF <br /> | ||
| + | **[[7mlh]] – hFab + Der p 2 <br /> | ||
| + | **[[7t0w]], [[7t0z]] – hFab + GABA – Cryo EM<br /> | ||
| + | **[[6ddm]], [[6ddv]] – hFab + MHC<br /> | ||
| + | **[[7pg8]], [[7pgb]] – hFab + Na+ channel<br /> | ||
| + | **[[7kzx]], [[7kzz]] – hFab + YiiP <br /> | ||
| + | **[[7amp]], [[7amq]], [[7amr]], [[7ams]] – hFab + T-cell receptor<br /> | ||
| + | **[[7dfp]] – hFab + Gi + dopamine receptor + drug – Cryo EM<br /> | ||
| + | **[[7lf7]], [[7lf8]], [[7lfa]], [[7lfb]], [[7lfd]] – hFab + ApoL <br /> | ||
| + | **[[7rth]] – hFab + hVHH <br /> | ||
| + | **[[7n0a]] – hFab + leukemia inhibitory factor <br /> | ||
| + | **[[6j6y]] – syFab + FGFR4<br /> | ||
| + | |||
| + | *Human Fab: viral protein complex | ||
| + | |||
| + | **[[6e3h]], [[6d0u]], [[5vag]], [[3gbm]], [[3gbn]], [[3lzf]], [[3fku]], [[3sdy]], [[3ztj]], [[3ztn]], [[4fp8]], [[4fqi]], [[4fqj]], [[4fqk]], [[4fql]], [[4fqr]], [[4fqv]], [[4fqy]], [[4gxu]], [[4nm8]], [[5gjt]], [[5gjs]], [[5dur]], [[5c0s]], [[4yk4]], [[4py8]], [[5wko]], [[5w6g]], [[5w0d]], [[5w08]], [[5v2a]], [[5umn]], [[5kaq]], [[6cnv]], [[6e4x]], [[6ii4]], [[6ii8]], [[6ii9]], [[6ml8]], [[6e56]], [[4r8w]], [[6iut]], [[6iuv]], [[6oc3]], [[6ocb]], [[6p3r]], [[6q0e]], [[6q0h]], [[6q0i]], [[6q0l]], [[6q0o]], [[6q18]], [[6uig]], [[6ur5]], [[6urm]], [[6uyn]], [[6wex]], [[6wez]], [[6wf0]], [[6wf1]], [[6wiz]], [[6wj1]], [[7kqg]], [[7kqh]], [[7kqi]], [[7u8j]], [[7u8l]], [[7u8m]] – hFab + Influenza virus hemagglutinin<br /> | ||
| + | **[[7k37]], [[7k39]], [[7k3a]], [[7k3b]], [[7kc1]], [[7l0l]], [[7mfg]], [[7scn]], [[7sco]], [[7x6l]], [[7x6o]] – hFab + Influenza virus hemagglutinin – Cryo EM<br /> | ||
| + | **[[6pze]], [[6pzf]], [[6pzy]], [[6pzz]], [[6q1z]], [[6q20]], [[6q23]], [[6u02]] – hFab + Influenza virus neuraminidase<br /> | ||
| + | **[[6pzw]], [[6pzy]], [[6pzz]], [[6v4n]], [[6v4o]] – hFab + Influenza virus neuraminidase – Cryo EM<br /> | ||
| + | **[[5gzo]], [[5gzn]], [[5lcv]], [[6nip]], [[6niu]], [[6plk]] – hFab + zika protein<br /> | ||
| + | **[[6lnt]], [[7bu8]], [[7bua]], [[7cbp]], [[7c2t]], [[7kcr]] – hFab + zika proteins – Cryo EM<br /> | ||
| + | **[[7bsd]] – hFab + zika virus NS1c <br /> | ||
| + | **[[7lse]], [[7lsf]] – hFab + tick-borne encephalitis virus proteins <br /> | ||
| + | **[[7lsg]], [[7sfv]], [[7sfw]] – hFab + tick-borne encephalitis virus proteins – Cryo EM<br /> | ||
| + | **[[6xob]] – hFab + eastern equine encephalitis virus protein - Cryo EM<br /> | ||
| + | **[[7ums]] – hFab + rotavirus proteins – Cryo EM<br /> | ||
| + | **[[5hj3]], [[5fhc]], [[6oz9]], [[6s8d]], [[6s8i]], [[6s8j]] – hFab + ebola envelope protein<br /> | ||
| + | **[[7kej]] – hFab + ebola spike glycoprotein – Cryo EM<br /> | ||
| + | **[[7kew]], [[7kex]], [[7kf9]], [[7kfb]], [[7kfe]], [[7kfh]], [[7m8l]], [[7swd]] – hFab + spike glycoprotein + ebola envelope protein – Cryo EM<br /> | ||
| + | **[[5n09]], [[4utb]], [[4uta]], [[4ut9]], [[4ut6]] – hFab + dengue virus envelope protein <br /> | ||
| + | **[[4c2i]], [[7bub]], [[7bud]], [[7bue]], [[7buf]], [[7c2s]], [[7v3g]], [[7v3h]], [[7v3i]], [[7v3j]] – hFab + dengue virus envelope protein - Cryo EM<br /> | ||
| + | **[[7bsc]] – hFab + dengue virus NS1c <br /> | ||
| + | **[[6vy4]], [[6vy6]] – hFab + Hendra virus protein<br /> | ||
| + | **[[6ute]] – hFab + West NIle virus protein<br /> | ||
| + | **[[6vy5]] – hFab + nipa virus receptor binding protein<br /> | ||
| + | **[[6blh]], [[6bli]], [[6oe4]], [[6ous]], [[6w52]] – hFab + RSV fusion protein<br /> | ||
| + | **[[7luc]], [[7lue]], [[7mpg]] – hFab + RSV fusion protein – Cryo EM<br /> | ||
| + | **[[7t8w]] – hFab + RSV glycoprotein <br /> | ||
| + | **[[6mjz]] – hFab + respirovirus fusion protein<br /> | ||
| + | **[[4dag]], [[7sem]] – hFab + metapneumovirus glycoprotein F0<br /> | ||
| + | **[[7tl0]], [[8cw9]] – hFab + metapneumovirus glycoprotein F0 – Cryo EM<br /> | ||
| + | **[[6p91]], [[6p95]], [[7s8h]] – hFab + lassa virus glycoprotein <br /> | ||
| + | **[[7tyv]], [[7uds]], [[7ul7]] – hFab + lassa virus glycoprotein – Cryo EM<br /> | ||
| + | **[[7t4s]] – hFab + HCMV glycoprotein – Cryo EM<br /> | ||
| + | **[[7l7r]] – hFab + hemorrhagic fever virus glycoprotein <br /> | ||
| + | **[[6yo6]] – hFab + LgHC3NB1<br /> | ||
| + | **[[7jie]] – hFab + norovirus VP1<br /> | ||
| + | **[[6gv4]] – hFab + parechovirus proteins + RNA - Cryo EM<br /> | ||
| + | **[[7d5z]], [[7kbb]] – hFab + herpesvirus proteins <br /> | ||
| + | **[[6c5v]], [[7fbi]], [[7kdd]], [[7lbe]], [[7lbf]], [[7lbg]], [[7m30]], [[7t4q]], [[7t4r]] – hFab + herpesvirus proteins - Cryo EM<br /> | ||
| + | **[[6b9j]] – syFab + vaccinia virus protein<br /> | ||
| + | **[[6otc]] – syFab + Marburg virus protein<br /> | ||
| + | **[[6svl]] – syFab + MYDGF<br /> | ||
| + | **[[7mmn]] – Fab + Escherichia virus protein<br /> | ||
| + | |||
| + | *Mouse Fab: protein complex | ||
| + | |||
| + | **[[1tzh]], [[1tzi]] - mFab + VEGF<br /> | ||
| + | **[[1fsk]], [[5vfy]], [[7n0v]] - mFab + pollen allergen<br /> | ||
| + | **[[3raj]] – mFab HB7 + CD38<br /> | ||
| + | **[[6u9s]] – mFab 5A6 + CD81<br /> | ||
| + | **[[7s11]], [[7s13]] – mFab + CD96<br /> | ||
| + | **[[3o0r]], [[5gux]] – mFab + nitric oxide reductase<br /> | ||
**[[1ahw]] - mFab 5G9+ tissue factor<br /> | **[[1ahw]] - mFab 5G9+ tissue factor<br /> | ||
| - | **[[ | + | **[[2w9e]], [[1tpx]], [[1tqb]], [[1tqc]], [[6aq7]], [[6suz]], [[6sv2]] – mFAB + major prion protein<br /> |
| - | + | ||
**[[2oz4]] – mFab + intercellular adhesion molecule<br /> | **[[2oz4]] – mFab + intercellular adhesion molecule<br /> | ||
**[[3eo1]] - mFab GC-1008 + transforming growth factor β-3<br /> | **[[3eo1]] - mFab GC-1008 + transforming growth factor β-3<br /> | ||
| + | **[[6z7w]], [[6z7y]], [[6z7z]] – mFab + insulin<br /> | ||
**[[4zxb]] – mFab 83 + insulin receptor<br /> | **[[4zxb]] – mFab 83 + insulin receptor<br /> | ||
**[[1egj]] – mFab + cytokine receptor<br /> | **[[1egj]] – mFab + cytokine receptor<br /> | ||
| Line 189: | Line 415: | ||
**[[1qfw]] – mFab + gonadotropin<br /> | **[[1qfw]] – mFab + gonadotropin<br /> | ||
**[[4cad]] – mFab + RCE1<br /> | **[[4cad]] – mFab + RCE1<br /> | ||
| - | **[[4m48]], [[4xpt]], [[4xph]], [[4xpg]], [[4xpf]], [[4xpb]], [[4xpa]], [[4xp9]], [[4xp6]], [[4xp5]], [[4xp4]], [[4xp1]], [[4xnx]], [[4xnu]] – mFab + dopamine transporter<br /> | + | **[[4m48]], [[4xpt]], [[4xph]], [[4xpg]], [[4xpf]], [[4xpb]], [[4xpa]], [[4xp9]], [[4xp6]], [[4xp5]], [[4xp4]], [[4xp1]], [[4xnx]], [[4xnu]], [[6m0f]], [[6m3z]], [[7wgd]], [[7wgt]], [[7wlw]] – mFab + dopamine transporter<br /> |
| - | **[[5i75]], [[5i74]], [[5i73]], [[5i71]], [[5i6z]], [[5i6x]] – mFab + serotonin transporter<br /> | + | **[[5i75]], [[5i74]], [[5i73]], [[5i71]], [[5i6z]], [[5i6x]], [[6awq]], [[6awp]], [[6awo]], [[6awn]], [[6w2b]], [[6w2c]] – mFab + serotonin transporter<br /> |
| + | **[[6dzv]], [[6dzw]], [[6dzy]], [[6dzz]], [[6vrh]], [[6vrk]], [[6vrl]], [[7li6]], [[7li7]], [[7li8]], [[7li9]], [[7lia]], [[7lwd]], [[7mgw]] – mFab + serotonin transporter – Cryo EM<br /> | ||
**[[1yjd]] – mFab 5.11A1 + CD28<br /> | **[[1yjd]] – mFab 5.11A1 + CD28<br /> | ||
**[[1sy6]] – mFab OKT3 + CD3<br /> | **[[1sy6]] – mFab OKT3 + CD3<br /> | ||
| Line 196: | Line 423: | ||
**[[4r0l]] – mFab + CD28<br /> | **[[4r0l]] – mFab + CD28<br /> | ||
**[[4qex]], [[4k2u]] – mFab + erythrocyte binding antigen<br /> | **[[4qex]], [[4k2u]] – mFab + erythrocyte binding antigen<br /> | ||
| - | **[[ | + | **[[2r9h]], [[6ad7]], [[6ad8]], [[6ada]], [[6adb]], [[6adc]], [[6k5a]], [[6k5i]], [[7cvs]], [[7cvt]] – mFab + exchange transporter ClCA<br /> |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
**[[1rjl]] – mFab + outer surface protein<br /> | **[[1rjl]] – mFab + outer surface protein<br /> | ||
**[[1mhh]] – mFab + protein L (mutant)<br /> | **[[1mhh]] – mFab + protein L (mutant)<br /> | ||
**[[1pg7]] – mFab 6A6 + hmFab D3H44<br /> | **[[1pg7]] – mFab 6A6 + hmFab D3H44<br /> | ||
| - | **[[1pkq]] – hFab/mFab 8-18C5 + myelin glycoprotein<br /> | ||
**[[2jel]] – mFab JEL42 + histidine-containing protein<br /> | **[[2jel]] – mFab JEL42 + histidine-containing protein<br /> | ||
**[[1nsn]] – mFab N10 + nuclease<br /> | **[[1nsn]] – mFab N10 + nuclease<br /> | ||
| - | **[[1rvf]] – mFab 17-IA + intact rhinovirus<br /> | ||
| - | **[[3j3o]], [[3j3p]]- mFab + poliovirus proteins – cryoEM<br /> | ||
| - | **[[1nfd]] – mFab H57 + T-cell receptor<br /> | ||
**[[1igc]] – mFab MOPC21 + streptococcal protein G<br /> | **[[1igc]] – mFab MOPC21 + streptococcal protein G<br /> | ||
**[[1iai]] – mFab idiotipic + mFab anti-idiotypic<br /> | **[[1iai]] – mFab idiotipic + mFab anti-idiotypic<br /> | ||
| + | **[[7jlk]], [[7jln]] – mFab anti-idiotypic + hFab<br /> | ||
**[[2r8s]] – mFab + RNA<br /> | **[[2r8s]] – mFab + RNA<br /> | ||
| - | **[[2fr4]], [[1xf2]], [[1xf3]], [[1xf4]], [[1i8m]], [[1cbv]] – mFab + DNA<br /> | + | **[[2fr4]], [[1xf2]], [[1xf3]], [[1xf4]], [[1i8m]], [[1cbv]], [[6idg]] – mFab + DNA<br /> |
| + | **[[7xlt]] – mFab + DNA + RNA – Cryo EM<br /> | ||
**[[1mhp]], [[3q3g]], [[3qa3]] – mFab + integrin<br /> | **[[1mhp]], [[3q3g]], [[3qa3]] – mFab + integrin<br /> | ||
| - | **[[ | + | **[[3etb]], [[7o85]] – mFab M18 (mutant) + anthrax-protective antigen<br /> |
| - | + | ||
**[[3f5w]], [[3pjs]], [[3efd]], [[3eff]], [[2hjf]], [[2w0f]], [[4msw]], [[4uuj]] – mFab + KcsA K+ channel<br /> | **[[3f5w]], [[3pjs]], [[3efd]], [[3eff]], [[2hjf]], [[2w0f]], [[4msw]], [[4uuj]] – mFab + KcsA K+ channel<br /> | ||
| - | **[[3stl]], [[3stz]], [[4i9w]], [[5ec2]], [[5ec1]], [[5ebw]], [[5ebm]], [[5ebl]], [[5e1a]] - mFab + KcsA K+ channel (mutant)<br /> | + | **[[3stl]], [[3stz]], [[4i9w]], [[5ec2]], [[5ec1]], [[5ebw]], [[5ebm]], [[5ebl]], [[5e1a]], [[6nfu]], [[6nfv]], [[6pa0]] - mFab + KcsA K+ channel (mutant)<br /> |
| - | **[[1kb5]] – mFab + T-cell receptor<br /> | + | **[[1kb5]], [[1nfd]] – mFab + T-cell receptor<br /> |
**[[4i18]] – mFab + pro-lactin receptor<br /> | **[[4i18]] – mFab + pro-lactin receptor<br /> | ||
**[[1uwx]] – mFab + protein G prime <br /> | **[[1uwx]] – mFab + protein G prime <br /> | ||
| Line 229: | Line 447: | ||
**[[5e94]] – mFab + glucagon-like receptor <br /> | **[[5e94]] – mFab + glucagon-like receptor <br /> | ||
**[[5e8d]] – mFab + proepiregulin <br /> | **[[5e8d]] – mFab + proepiregulin <br /> | ||
| - | **[[5kvg]], [[5kvf]], [[5kve]], [[5kvd]], [[5jhl]] – mFab + zika envelope DIII <br /> | ||
| - | **[[5jym]] – mFab + cadherin<br /> | ||
**[[5fb8]] - mFab + interleukin<br /> | **[[5fb8]] - mFab + interleukin<br /> | ||
**[[5d96]], [[5d93]] - mFab + sulfhydryl oxidase<br /> | **[[5d96]], [[5d93]] - mFab + sulfhydryl oxidase<br /> | ||
**[[4ybq]] – mFab + fructose transporter<br /> | **[[4ybq]] – mFab + fructose transporter<br /> | ||
| - | **[[4xzu]] - mFab + coagulation factor <br /> | + | **[[4xzu]], [[7kbt]] - mFab + coagulation factor <br /> |
**[[4u6h]] - mFab + virion membrane protein M25 <br /> | **[[4u6h]] - mFab + virion membrane protein M25 <br /> | ||
**[[4r9y]], [[4r97]] - mFab + platelet factor 4<br /> | **[[4r9y]], [[4r97]] - mFab + platelet factor 4<br /> | ||
**[[4qww]] - mFab + acetylcholinesterase <br /> | **[[4qww]] - mFab + acetylcholinesterase <br /> | ||
**[[4qti]] – mFab + urokinase-type plasminogen activator <br /> | **[[4qti]] – mFab + urokinase-type plasminogen activator <br /> | ||
| - | **[[ | + | **[[5vco]] – mFab + peptidase<br /> |
**[[4p3d]], [[4p3c]] – mFab + metalloproteinase 14<br /> | **[[4p3d]], [[4p3c]] – mFab + metalloproteinase 14<br /> | ||
**[[4ong]], [[4onf]] - mFab + amyloid-β A4 protein<br /> | **[[4ong]], [[4onf]] - mFab + amyloid-β A4 protein<br /> | ||
**[[4oii]] - mFab + NS1<br /> | **[[4oii]] - mFab + NS1<br /> | ||
| - | **[[3fmg]] – mFab + glycoprotein VP7<br /> | + | **[[5ldn]] – mFab + hexon C5<br /> |
| - | **[[ | + | **[[5ldn]] – mFab + MIG-C4<br /> |
| - | **[[ | + | **[[6vx4]] – mFab + toxins – Cryo EM<br /> |
| + | **[[6elu]] – mFab + Trypanosoma protein<br /> | ||
| + | **[[6k65]] – mFab + immunoglobulin G-binding protein<br /> | ||
| + | **[[6ks0]], [[6ks1]] – mFab + adiponectin receptor protein<br /> | ||
| + | **[[7dr4]] – mFab + IL-2<br /> | ||
| + | **[[6sxi]] – mFab + scFv<br /> | ||
| + | **[[6z2l]] – mFab + P113<br /> | ||
| + | **[[7kr5]] – mFab + CRAC – Cryo EM<br /> | ||
| + | **[[6nyq]] – mFab + GLMP<br /> | ||
| + | **[[6vtw]] – mFab + RSV S4<br /> | ||
| + | **[[7st8]] – mFab + SAS1B<br /> | ||
| + | **[[7vae]], [[7vaf]], [[7vag]], [[7wsi]] – mFab + NTCP – Cryo EM<br /> | ||
| + | **[[7xw6]] – mFab in ML109 complex – Cryo EM<br /> | ||
| + | **[[7lr3]], [[7lr4]] – mFab + hapless 2<br /> | ||
| + | **[[7kpj]] – mFab + Crohn diseae protein<br /> | ||
| + | **[[7c4s]] – mFab + S1P3<br /> | ||
| + | **[[7k7h]], [[7k7i]] – mFab + PltB – Cryo EM<br /> | ||
| + | **[[7rah]] – mFab + adenylate cyclase toxin<br /> | ||
| + | **[[7sbd]], [[7sbg]] – mFab + profilin<br /> | ||
| + | **[[7n0u]] – mFab + bet v 1<br /> | ||
| + | **[[7r9d]] – mFab + viVHH<br /> | ||
| + | **[[7jgj]] – mFab + IgA1<br /> | ||
| + | **[[7rd5]] – mFab + tetraspanin<br /> | ||
| + | **[[7te6]] – mFab + NMDA<br /> | ||
| + | **[[7te9]], [[7teb]], [[7tee]], [[7teq]], [[7ter]], [[7tes]], [[7tet]] – mFab + NMDA – Cryo EM<br /> | ||
| + | **[[7tuf]], [[7tug]] – mFab + tapasin<br /> | ||
| + | |||
| + | *Mouse Fab: viral protein complex | ||
| + | |||
| + | **[[6a0z]], [[1eo8]], [[1ken]], [[4mhh]], [[4mhj]], [[6n5b]], [[6n5d]] - mFab anti-influenza virus hemagglutinin<br /> | ||
| + | **[[4qnp]], [[1nca]], [[1ncb]], [[1ncc]], [[1ncd]] – mFab + influenza neuraminidase<br /> | ||
| + | **[[6n5e]], [[7fah]] – mFab + influenza hemagglutinin <br /> | ||
| + | **[[6wzt]], [[7dkj]], [[7jix]], [[7yhk]] – mFab + influenza hemagglutinin – Cryo EM<br /> | ||
| + | **[[1rvf]] – mFab 17-IA + intact rhinovirus<br /> | ||
| + | **[[3j3o]], [[3j3p]]- mFab + poliovirus proteins – cryoEM<br /> | ||
| + | **[[6mui]], [[6mw9]], [[6mwc]], [[6mwv]], [[6mwx]] - mFab + equine encephalitis virus proteins – cryoEM<br /> | ||
| + | **[[5kvg]], [[5kvf]], [[5kve]], [[5kvd]], [[5jhl]], [[6uta]] – mFab + zika envelope DIII <br /> | ||
| + | **[[3ve0]] - mFab + Ebola envelope glycoprotein<br /> | ||
| + | **[[5y9t]], [[5y9c]], [[5y9f]], [[7ew5]] – mFab + papilloma virus capsid protein<br /> | ||
| + | **[[4l5f]], [[6fla]], [[6flb]], [[6flc]] – mFab + dengue virus envelope protein <br /> | ||
| + | **[[5zud]], [[5zuf]], [[6aj7]], [[6aj9]] – mFab + enterovirus caspid proteins – Cryo EM<br /> | ||
| + | **[[3fmg]] – mFab + rotavirus glycoprotein VP7<br /> | ||
| + | **[[3ixx]], [[3ixy]] - mFab E53 + envelope glycoprotein + West Nile virus peptide<br /> | ||
| + | **[[7ki6]] – mFab + Hendra virus F0 – Cryo EM<br /> | ||
| + | **[[7ki4]], [[7txz]], [[7ty0]] – mFab + nipah virus protein – Cryo EM<br /> | ||
| + | **[[7rfp]] – mFab + muromegalovirus GITR – Cryo EM<br /> | ||
| + | **[[7u9g]], [[8a1e]] – mFab + rabies virus glycoprotein – Cryo EM<br /> | ||
| + | **[[7kyl]] – mFab + deer tick virus glycoprotein <br /> | ||
| + | **[[7c80]], [[7c81]], [[7eaj]], [[7eak]], [[7cmk]] – mFab + echovirus glycoproteins – Cryo EM<br /> | ||
| + | **[[7m3l]], [[7m3m]], [[7m3n]] – mFab + parvovirus glycoproteins – Cryo EM<br /> | ||
| + | **[[7qu1]] – mFab + marchupovirus glycoproteins <br /> | ||
| + | **[[7qu2]] – mFab + mammarenavirus glycoproteins <br /> | ||
| + | **[[7dq7]] – mFab + coxsackievirus proteins – Cryo EM<br /> | ||
| + | |||
| + | *Anti-HIV Fab: protein complex or broadly neutralizing antibody complex | ||
| + | |||
| + | **[[3mac]], [[3ma9]], [[6fy1]] – hFab anti-HIV 8062 + transmembrane glycoprotein<br /> | ||
| + | **[[3idx]], [[3idy]], [[2ny7]], [[4jpw]], [[4lsp]], [[4lsq]], [[4lsr]], [[4lss]], [[4lst]], [[4lsu]], [[4lsv]], [[5te4]], [[5fyl]], [[5f9w]], [[5f96]], [[5f6j]], [[4ywg]], [[4ye4]], [[4ydl]], [[4ydk]], [[4ydj]], [[4ydi]], [[4yc2]], [[4ybl]], [[4s1s]], [[4s1r]], [[4s1q]], [[4rwy]], [[4rfn]], [[5w4l]], [[6w4m]], [[6bck]], [[6bf4]], [[6d2p]], [[6db5]], [[6oej]], [[6ofi]], [[7klc]], [[7rdw]] - hFab anti-HIV + gp120 core<br /> | ||
| + | **[[6b0n]] - hFab anti-HIV + gp140<br /> | ||
| + | **[[5v7j]], [[4j6r]] - hFab anti-HIV + gp160<br /> | ||
| + | **[[6dfg]], [[6dfh]], [[6e5p]], [[6pwu]] - hFab anti-HIV + gp160 – Cryo EM<br /> | ||
| + | **[[4xnz]], [[4xny]], [[4xmp]], [[7ekb]], [[7n05]], [[7n08]] - hFab anti-HIV + gp41<br /> | ||
| + | **[[7n65]] - hFab anti-HIV + gp41 – Cryo EM<br /> | ||
| + | **[[3lqa]], [[2qad]] - hFab anti-HIV + CD4 + gp41<br /> | ||
| + | **[[5jsa]], [[5js9]], [[5c7k]], [[5v8l]], [[5v8m]], [[6ccb]], [[6mft]], [[6orn]], [[6oro]], [[6orp]], [[6orq]], [[6utk]], [[6v6w]], [[7kmd]], [[7ucf]] - hFab anti-HIV + gp41 + gp120<br /> | ||
| + | **[[6nij]], [[6nqd]], [[6ulc]], [[6um5]], [[6um6]], [[6um7]], [[6vo3]], [[6vy2]], [[7kde]], [[7lg6]], [[7ll1]], [[7ll2]], [[7llk]], [[7pc2]], [[7rsn]], [[7rso]], [[7tfo]] - hFab anti-HIV + gp41 + gp120 – Cryo EM<br /> | ||
| + | **[[6opa]], [[6oz4]] - hFab anti-HIV + gp41 + gp160<br /> | ||
| + | **[[6ozc]], [[7sq1]] - hFab anti-HIV + gp41 + gp160 – Cryo EM<br /> | ||
| + | **[[6u0l]], [[6u0n]] - hFab anti-HIV + gp41 + gp160 + CD4 – Cryo EM<br /> | ||
| + | **[[4r4n]], [[4r4f]], [[6mg7]], [[6w4m]] - hFab anti-HIV + gp120 + M48U1<br /> | ||
| + | **[[7lok]] - hFab anti-HIV + gp120 + gp41 + M48U1 – Cryo EM<br /> | ||
| + | **[[6vpx]] - hFab anti-HIV + gp41 + gp120 + MPER peptide – Cryo EM<br /> | ||
| + | **[[5tfw]], [[5t85]], [[5t80]], [[5t6l]], [[5t5b]], [[5t29]] - hFab anti-HIV + T117V2<br /> | ||
| + | **[[2x7l]] – hFab anti-HIV + HIV REV<br /> | ||
| + | **[[6cdm]], [[6cdo]], [[6cdp]], [[6ch8]], [[6ch9]], [[6chb]], [[6ck9]], [[6cxg]], [[6fy2]], [[6muf]], [[6myy]], [[6mzj]], [[6w03]] – hFab anti-HIV + HIV protein<br /> | ||
| + | **[[6cde]], [[6cdi]], [[6edu]], [[7n28]] – hFab anti-HIV + HIV protein – Cryo EM<br /> | ||
| + | **[[7lua]] – hFab anti-HIV + sHIV protein + gp120 – Cryo EM<br /> | ||
| + | **[[6uuh]] – hFab anti-HIV + IggG<br /> | ||
| + | **[[6mam]] – hFab anti-HIV + ebola glycoprotein<br /> | ||
| + | **[[6qd7]], [[6qd8]] – hFab anti-HIV + ebola glycoprotein – Cryo EM<br /> | ||
| + | **[[6id4]], [[7re7]] – hFab anti-HIV + MHC antigen + beta-2-microglobulin<br /> | ||
| + | **[[3bqu]] – hFab 2F5 anti-HIV + mFab 3H6<br /> | ||
| + | **[[6ce0]], [[6vlw]], [[6w16]], [[7mxd]] – hFab + HIV-1 protein<br /> | ||
| + | **[[7ly9]], [[7ucg]] – hFab + HIV-1 envelope protein – Cryo EM<br /> | ||
| + | **[[1g9m]], [[1g9n]], [[1gc1]], [[2i5y]], [[2i60]], [[2nxy]], [[2nxz]], [[2ny0]], [[2ny1]], [[2ny2]], [[2ny3]], [[2ny4]], [[2ny5]], [[2ny6]], [[3jwd]], [[3jwo]], [[5a8h]], [[5a7x]], [[4r4h]], [[4h8w]] - hFab anti-HIV + envelope glycoprotein gp120 + CD4<br /> | ||
| + | **[[6mtj]], [[6mtn]], [[6mu6]], [[6mu7]], [[6mu8]], [[6mug]] - hFab anti-HIV + HIV proteins + inhibitor<br /> | ||
| + | **[[7l86]], [[7l87]], [[7l88]], [[7l89]], [[7l8a]], [[7l8b]], [[7l8c]], [[7l8d]], [[7l8f]], [[7l8g]], [[7l8s]], [[7l8t]], [[7l8u]], [[7l8w]], [[7l8x]], [[7l8y]], [[7l8z]], [[7l90]], [[7lu9]], [[7mxe]] - rmFab anti-HIV + gp41 + gp120 – Cryo EM<br /> | ||
| + | **[[7l8e]] - rmFab anti-HIV + gp160 – Cryo EM<br /> | ||
| + | **[[6vkn]], [[6vn0]], [[6xrt]], [[7tfn]] - rmFab anti-HIV + gp41 + gp160 – Cryo EM<br /> | ||
| + | **[[6vlr]], [[7n0x]], [[7n8q]] – rmFab anti-HIV + HIV protein<br /> | ||
| + | **[[6xcj]] - rmFab anti-HIV + gp120 core<br /> | ||
| + | **[[6pw6]], [[6vo1]] - bFab anti-HIV + gp41 + gp120 – Cryo EM<br /> | ||
| + | **[[1afv]] – mFab anti-HIV + capsid protein C<br /> | ||
| + | **[[6p8m]], [[7jks]], [[7jkt]] - mFab anti-HIV + gp120 core<br /> | ||
| + | **[[6cez]], [[6p65]], [[6vo0]] – rFab anti-HIV + HIV protein – Cryo EM<br /> | ||
| + | **[[5dhz]], [[5dhy]], [[5dhx]], [[5dhv]], [[6cbp]], [[6nnf]] – hscFv anti-HIV + HIV protein<br /> | ||
| + | **[[3rjq]], [[7r73]], [[7r74]], [[7ri1]], [[7ri2]] – LgVHH anti-HIV + gp120<br /> | ||
| + | **[[7lpn]] – LgVHH anti-HIV + gp160 + gp41<br /> | ||
| + | **[[2xt1]], [[2xxm]] – ViVHH anti-HIV + HIV capsid<br /> | ||
| + | |||
| + | *Other Fab: protein complex | ||
| + | |||
| + | **[[3ld8]], [[3ldb]] – AhFab + bifunctional arginine demethylase <br /> | ||
**[[3mj9]] – AhFab HL4E10 + JAML <br /> | **[[3mj9]] – AhFab HL4E10 + JAML <br /> | ||
**[[3r08]] - AhFab 2C11 + CD3ε<br /> | **[[3r08]] - AhFab 2C11 + CD3ε<br /> | ||
| - | **[[ | + | **[[1jps]] - hmFab D3H44 + tissue factor<br /> |
| - | **[[ | + | **[[5f3h]], [[5f3b]] - hmFab + growth factor 8<br /> |
| - | + | **[[1pkq]] – hmFab 8-18C5 + myelin glycoprotein<br /> | |
| - | + | **[[2b2x]] – rFab AQC2 + integrin<br /> | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | **[[ | + | |
| - | + | ||
| - | **[[ | + | |
| - | + | ||
**[[4ht1]] – rFab + TNF ligand 12 <br /> | **[[4ht1]] – rFab + TNF ligand 12 <br /> | ||
| + | **[[6cf2]] – rFab + REV<br /> | ||
| + | **[[2r56]] – bFab igE + β-lactoglobulin <br /> | ||
| + | **[[1g6v]] – bFab + carbonic anhydrase<br /> | ||
| + | **[[7eo0]], [[7fei]], [[7fej]] – bFab + FMD virus proteins – Cryo EM<br /> | ||
**[[4n9g]] - rmFab + scaffold<br /> | **[[4n9g]] - rmFab + scaffold<br /> | ||
| + | **[[6xgc]] – rmFab + Influenza virus hemagglutinin – Cryo EM<br /> | ||
| + | **[[7nks]], [[7nrh]], [[7o9s]] - rFab + hantavirus envelope polyprotein <br /> | ||
| + | **[[6z06]] - vFab + hantavirus envelope polyprotein – vole <br /> | ||
| + | **[[7b09]] - vFab + hantavirus envelope polyprotein – Cryo EM<br /> | ||
| + | **[[6oor]] – raFab + β-2-microglobulin + CD1D<br /> | ||
| + | **[[6e62]] – raFab + malaria protein<br /> | ||
| + | **[[6qig]] – raFab + ADAMTS-13<br /> | ||
| + | **[[6al0]], [[6al1]] – raFab + S2P<br /> | ||
| + | **[[7k22]], [[7k23]] – raFab + VP1 – Cryo EM<br /> | ||
| + | **[[7kq7]] – raFab + IL21R<br /> | ||
| + | **[[6gku]] – LgFab + galectin<br /> | ||
| + | **[[4hgk]] – Fab + albumin – shark<br /> | ||
| + | **[[6vi1]] – syFab + terminase<br /> | ||
| + | **[[6iap]] – syFab + Nkp46<br /> | ||
| + | **[[7mdj]] - syFab + KcsA K+ channel + ion<br /> | ||
| + | **[[7keo]] – syFab igG1 + ubiquitin<br /> | ||
| + | **[[6i8s]] - EcFab + plasminogen activator inhibitor – Escherichia coli<br /> | ||
| + | **[[6pis]] – Fab + TRAAK – Cricetulus migratorius<br /> | ||
| + | **[[7y7m]], [[7yms]], [[7yrf]], [[7yrh]] – Fab + coxsackievirus proteins – Cryo EM<br /> | ||
| - | *Fab: protein higher complexes | + | *Human Fab: protein higher complexes |
| - | **[[3ixx]], [[3ixy]] - mFab E53 + envelope glycoprotein + West Nile virus peptide<br /> | ||
| - | **[[1g9m]], [[1g9n]], [[1gc1]], [[2i5y]], [[2i60]], [[2nxy]], [[2nxz]], [[2ny0]], [[2ny1]], [[2ny2]], [[2ny3]], [[2ny4]], [[2ny5]], [[2ny6]], [[3jwd]], [[3jwo]], [[5a8h]], [[5a7x]], [[4r4h]] - hFab anti-HIV + envelope glycoprotein gp120 + CD4<br /> | ||
| - | **[[5jsa]], [[5js9]], [[5c7k]] - hFab anti-HIV + envelope glycoprotein gp120 + gp41<br /> | ||
| - | **[[4r4n]], [[4r4f]] - hFab anti-HIV + envelope glycoprotein gp120 + M48U1 peptide<br /> | ||
**[[2wuc]] - hFab 40 + hepatocyte growth factor activator + inhibitor<br /> | **[[2wuc]] - hFab 40 + hepatocyte growth factor activator + inhibitor<br /> | ||
| - | **[[3lqa]], [[2qad]] - hFab anti-HIV + CD4 + gp41<br /> | ||
**[[3d85]] - hFab 7G10 + IL-12 + IL-23<br /> | **[[3d85]] - hFab 7G10 + IL-12 + IL-23<br /> | ||
**[[4xwo]] - hFab + ATPase GET3 + Sec22<br /> | **[[4xwo]] - hFab + ATPase GET3 + Sec22<br /> | ||
| Line 279: | Line 604: | ||
**[[4xtr]] - hFab + ATPase GET3 + PEP12P peptide<br /> | **[[4xtr]] - hFab + ATPase GET3 + PEP12P peptide<br /> | ||
**[[4xmn]] - hFab + Sec13 + Nup145 + Nup84 + Nup120 + Nup85<br /> | **[[4xmn]] - hFab + Sec13 + Nup145 + Nup84 + Nup120 + Nup85<br /> | ||
| - | **[[ | + | **[[4xmm]] - hFab + Sec13 + Nup145 + Nup84 + Nup120 + Nup85 + SEH1<br /> |
**[[4mxw]] - hFab + TNFR-III + lymphotoxin<br /> | **[[4mxw]] - hFab + TNFR-III + lymphotoxin<br /> | ||
**[[3bt2]] – hFab anti-UPAR + urokinase-type plasminogen activator + vitronectin<br /> | **[[3bt2]] – hFab anti-UPAR + urokinase-type plasminogen activator + vitronectin<br /> | ||
| + | **[[6cw2]] – hFab + histone acetyltransferase + transcriptional adapter<br /> | ||
| + | **[[6c08]] – hFab + amino acid transporter + Arg<br /> | ||
| + | **[[6apd]] – hFab + RSV fusion protein + immunoglobulin + IGL <br /> | ||
| + | **[[6w51]] – hFab + 2-b-microglobulin + MHC + p53 peptide<br /> | ||
| + | **[[7bbg]] – hFab + 2-b-microglobulin + MHC + wilms tumor peptide<br /> | ||
**[[3gjf]], [[3hae]] – hFab + β-2-microglobulin + MHC antigen + NYESO peptide<br /> | **[[3gjf]], [[3hae]] – hFab + β-2-microglobulin + MHC antigen + NYESO peptide<br /> | ||
| - | **[[3gb7]], [[2p7t]], [[2h8p]], [[2hfe]], [[2atk]], [[4wfh]], [[4wfg]], [[4wff]], [[4wfe]] - mFab + KcsA K+ channel + ion<br /> | + | **[[7bh8]] – hFab + 2-b-microglobulin + MHC + VL9 peptide<br /> |
| + | **[[6o1f]] - hFab + trypsin inhibitor + tryptase<br /> | ||
| + | **[[7joo]] - hFab + LgVHH + ICOS<br /> | ||
| + | **[[6fn1]], [[7a65]], [[7a69]], [[7a6c]], [[7a6e]], [[7a6f]] – hFab + ABCB + drug<br /> | ||
| + | **[[6w9g]] - hFab + CD40 + fluorescent amino acid<br /> | ||
| + | **[[6ww2]] – hFab + syVHH + frizzled-5 – Cryo EM<br /> | ||
| + | **[[7tdm]], [[7tdn]] – hFab + claudin + enterotoxin – Cryo EM<br /> | ||
| + | **[[7mhy]] – hFab + HHAT + palmitoyl-CoA – Cryo EM<br /> | ||
| + | **[[7ncs]], [[7nd0]] – hFab in BAM complex – Cryo EM<br /> | ||
| + | |||
| + | *Mouse Fab: protein higher complexes | ||
| + | |||
| + | **[[5w3e]], [[5w3l]], [[5w3m]], [[5w3o]], [[5w3p]] - mFab C5 + Rhinovirus protein 1 + protein 2 + protein 3 + protein 4<br /> | ||
| + | **[[3gb7]], [[2p7t]], [[2h8p]], [[2hfe]], [[2atk]], [[4wfh]], [[4wfg]], [[4wff]], [[4wfe]], [[5vk6]], [[5vke]], [[5vkh]], [[6by2]], [[6by3]] - mFab + KcsA K+ channel + ion<br /> | ||
**[[3or6]], [[3or7]], [[3ogc]], [[3fb7]], [[3f7v]], [[3f7y]], [[3fb5]], [[3fb6]], [[3fb8]], [[3iga]], [[2itc]], [[2itd]], [[2nlj]], [[2bob]], [[2boc]], [[1s5h]], [[1r3i]], [[1r3j]], [[1r3k]], [[1r3l]], [[1k4c]], [[1k4d]], [[3hpl]] - mFab + KcsA K+ channel (mutant) + ion<br /> | **[[3or6]], [[3or7]], [[3ogc]], [[3fb7]], [[3f7v]], [[3f7y]], [[3fb5]], [[3fb6]], [[3fb8]], [[3iga]], [[2itc]], [[2itd]], [[2nlj]], [[2bob]], [[2boc]], [[1s5h]], [[1r3i]], [[1r3j]], [[1r3k]], [[1r3l]], [[1k4c]], [[1k4d]], [[3hpl]] - mFab + KcsA K+ channel (mutant) + ion<br /> | ||
**[[2fd6]] – mFab ATN-615 + urokinase-type plasminogen activator + urokinase plasminogen receptor<br /> | **[[2fd6]] – mFab ATN-615 + urokinase-type plasminogen activator + urokinase plasminogen receptor<br /> | ||
| + | **[[4k24]] – mFab + urokinase-type plasminogen activator + urokinase plasminogen receptor + vitronectin<br /> | ||
**[[1j5o]] – mFab + reverse transcriptase + DNA<br /> | **[[1j5o]] – mFab + reverse transcriptase + DNA<br /> | ||
**[[1qkz]] – mFab + protein G prime + major outer membrane protein peptide<br /> | **[[1qkz]] – mFab + protein G prime + major outer membrane protein peptide<br /> | ||
**[[2ibz]] – mFab + cytochrome bc1 complex + stigmatellin <br /> | **[[2ibz]] – mFab + cytochrome bc1 complex + stigmatellin <br /> | ||
| - | **[[ | + | **[[6jmq]], [[6jmr]] – mFab + large neutral amino acid transporter + 4f2 cell-surface antigen<br /> |
| - | **[[ | + | **[[6qno]] - mFab + guanine nucleotide-binding protein + transducin + rhodopsin – Cryo EM<br /> |
| - | **[[ | + | **[[7k78]] - mFab + yeast nucleosome – Cryo EM<br /> |
| - | **[[ | + | **[[7rxc]], [[7rxd]] - mFab + viVVH + ER lumen receptors – Cryo EM<br /> |
| + | **[[7c6a]] – mFab + angiotensin receptor + SAR1<br /> | ||
| + | **[[6gff]] – mFab + TGF + GARPIN<br /> | ||
| + | **[[7kpb]] – mFab + TNF + TNFR<br /> | ||
| + | **[[7df9]], [[7dfa]], [[7dfb]], [[7dfc]] – mFab + arrestin + arrestin receptor<br /> | ||
*Full Immunoglobulin | *Full Immunoglobulin | ||
| Line 299: | Line 647: | ||
**[[1iga]] - hIgA1 - model<br /> | **[[1iga]] - hIgA1 - model<br /> | ||
| - | *Fc Fragments | + | *Fc Fragments or immunoglobulin gamma-1 heavy chain |
| - | **[[3dnk]] - hFc | + | **[[3dnk]] - hFc Igg1<br /> |
**[[1qp1]] – hFc BRE<br /> | **[[1qp1]] – hFc BRE<br /> | ||
**[[3muh]] – hFc PG9<br /> | **[[3muh]] – hFc PG9<br /> | ||
| Line 307: | Line 655: | ||
**[[1f6a]] - hFc IgE + high-affinity receptor Fc (ε) RI (α)<br /> | **[[1f6a]] - hFc IgE + high-affinity receptor Fc (ε) RI (α)<br /> | ||
**[[1fp5]] - hFc IgE C ε 3-C ε 4<br /> | **[[1fp5]] - hFc IgE C ε 3-C ε 4<br /> | ||
| + | **[[6cjx]], [[6f2z]], [[6x3i]] - hFc (mutant) <br /> | ||
| + | **[[6iqg]], [[7mfr]] - hFc + peptide<br /> | ||
| + | **[[6d4i]] - rmFc Igg2<br /> | ||
| + | **[[6d4e]], [[6d4m]] - rmFc Igg3<br /> | ||
| + | **[[6d4n]] - rmFc Igg4<br /> | ||
*Fv Fragments | *Fv Fragments | ||
| + | **[[3zhd]], [[3zhk]], [[3zhl]] – hFv scaffold<br /> | ||
| + | **[[4u3x]] – hFv + lysozyme<br /> | ||
**[[3dur]], [[3dus]], [[3duu]], [[3dv4]], [[3dv6]] – mFv + Ig-like protein<br /> | **[[3dur]], [[3dus]], [[3duu]], [[3dv4]], [[3dv6]] – mFv + Ig-like protein<br /> | ||
| - | **[[3h3b]] – mFv + ERBB2<br /> | ||
**[[3hb3]] – mFv + cytochrome c oxidase subunit 1-β<br /> | **[[3hb3]] – mFv + cytochrome c oxidase subunit 1-β<br /> | ||
**[[1qle]] - mFv + cytochrome c oxidase<br /> | **[[1qle]] - mFv + cytochrome c oxidase<br /> | ||
| - | **[[ | + | **[[6oik]] - mFv + AChR + guanine nucleotide-binding protein + transducin – Cryo EM<br /> |
| - | **[[3tpk]] – | + | |
| - | **[[ | + | * Single chain variable fragment (scFv) |
| - | **[[ | + | |
| - | **[[1mel]], [[1rjc]], [[1zvy]] – | + | **[[6ehy]], [[6ehv]], [[6ehw]], [[6ehx]], [[5c2b]], [[5wym]], [[1x9q]], [[2a9m]], [[3kdm]], [[4buh]], [[3u6r]], [[3auv]], [[6qb9]], [[6qf9]], [[6vrp]], [[7ah1]] – hscFv <br /> |
| - | **[[4u3x]] – | + | **[[4x4x]], [[6dn0]], [[2a9n]], [[6vun]], [[6vuo]], [[6vup]], [[7kbm]], [[7kbo]], [[7kpb]] – hscFv (mutant)<br /> |
| + | **[[6ffj]] – hscFv anti-tumor<br /> | ||
| + | **[[6uup]], [[6uy3]] – cscFv - camel <br /> | ||
| + | **[[6pil]], [[6psc]] – rscFv <br /> | ||
| + | **[[1h8n]], [[1lmk]], [[1nqb]],[[4h0g]], [[4nkd]], [[4nkm]], [[4nko]], [[3nn8]], [[3bd3]], [[3bd4]], [[3bd5]], [[2gjj]], [[5b3n]], [[4laq]], [[4gqp]], [[3umt]], [[6s2i]], [[6tnp]], [[7aql]], [[7eq3]] – mscFv <br /> | ||
| + | **[[1p4i]] – mscFv (mutant)<br /> | ||
| + | **[[4p49]], [[4p48]], [[4ouo]], [[5vf6]] – scFv - chicken<br /> | ||
| + | **[[6wzn]] – syscFv <br /> | ||
| + | |||
| + | * Single chain variable fragment complex | ||
| + | |||
| + | **[[5lbs]] – hscFv + zika envelope protein E<br /> | ||
| + | **[[5ljy]] – hscFv + Hantaan virus envelope protein<br /> | ||
| + | **[[6pcu]] – hscFv + rotavirus capsid protein<br /> | ||
| + | **[[7cth]] – hscFv + dengue protein – Cryo EM<br /> | ||
| + | **[[4nik]] – hscFv + gankyrin<br /> | ||
| + | **[[5jz7]] – hscFv + NGF<br /> | ||
| + | **[[4kv5]] – hscFv + TGF<br /> | ||
| + | **[[5iwl]] – hscFv + CD47<br /> | ||
| + | **[[6tou]] – hscFv + rabies glycoprotein<br /> | ||
| + | **[[6ikm]] – hscFv + polyamine transport protein<br /> | ||
| + | **[[2ybr]], [[2yc1]] – hscFv + CN2 toxin<br /> | ||
| + | **[[5ujz]], [[5uk0]], [[5uk1]], [[5uk2]] - hscFv + hemagglutinin – Cryo EM<br /> | ||
| + | **[[4v1d]] - hscFv + mammal toxin CN2 <br /> | ||
| + | **[[6i07]] – hscFv + EpCAM<br /> | ||
| + | **[[6kn9]] – hscFv + IL-18R<br /> | ||
| + | **[[5d9q]] – hscFv + antibody + gp120 + gp40<br /> | ||
| + | **[[7jum]] – hscFv + P230<br /> | ||
| + | **[[7tzg]], [[7tzh]] – hscFv + LAG3<br /> | ||
| + | **[[7xw7]] – hscFv + thyrotropin receptor – Cryo EM<br /> | ||
| + | **[[6e0c]], [[6e0p]] - hscFv in nucleosome – Cryo EM<br /> | ||
| + | **[[8dpf]], [[8dpg]], [[8dph]], [[8dpi]] – hscFv + Gi + 5HT2C receptor + drug – Cryo EM<br /> | ||
| + | **[[7jvr]] – hscFv + Gi + dopamine receptor + drug – Cryo EM<br /> | ||
| + | **[[7tuz]] – hscFv + Gi + GPR183 + drug – Cryo EM<br /> | ||
| + | **[[7d3k]], [[7d3l]], [[7d3m]], [[7d3r]] – bscFv + FMDV proteins – Cryo EM<br /> | ||
| + | **[[3ab0]] – mscFv + BCLA protein<br /> | ||
| + | **[[5jyl]], [[5jym]] – mscFv + cadherin<br /> | ||
| + | **[[5f3j]] – mscFv + duffy receptor<br /> | ||
| + | **[[5dfw]], [[6ejg]], [[6ejm]], [[6ek2]] – mscFv + CD81<br /> | ||
| + | **[[2kh2]] – mscFv + IL-1 - NMR<br /> | ||
| + | **[[4yqx]] – mscFv + IL-2<br /> | ||
| + | **[[3h3b]] – mscFv + ERBB2<br /> | ||
| + | **[[5ogi]] – mscFv + hexon protein <br /> | ||
| + | **[[3h3b]], [[6eqc]] – mscFv + hexon protein – Cryo EM<br /> | ||
| + | **[[7rkf]], [[7rkm]], [[7rkn]], [[7rkx]], [[7rky]] – mscFv + Gi + US27 – Cryo EM<br /> | ||
| + | **[[7xmt]] – mscFv + Gi + SSTR4 – Cryo EM<br /> | ||
| + | **[[7jhj]] – mscFv + Gi + BILF1 – Cryo EM<br /> | ||
| + | **[[4f9p]], [[4f9l]] – mscFv + BTN3A1<br /> | ||
| + | **[[5aam]], [[5aaw]], [[7k93]] – mscFv + Dengue virus envelope protein<br /> | ||
| + | **[[5kov]] – mscFv + Astrovirus envelope protein<br /> | ||
| + | **[[7rk1]] – mscFv + Astrovirus VP70<br /> | ||
| + | **[[7rk2]] – mscFv + Astrovirus VP25<br /> | ||
| + | **[[6h3t]], [[6h3u]] – mscFv + bovine schmallenberg virus envelope protein<br /> | ||
| + | **[[1dzb]], [[2znx]] – mscFv + lysozyme<br /> | ||
| + | **[[1a14]], [[1nmc]] – mscFv + neuraminidase<br /> | ||
| + | **[[5gs2]] – mscFv + MBP + repebody<br /> | ||
| + | **[[1fo0]], [[1kj2]], [[1nam]] – mscFv + TCR + MHC + peptide<br /> | ||
| + | **[[7k5x]], [[7k5y]], [[7k60]], [[7k61]], [[7k63]] - mscFv + human nucleosome – Cryo EM<br /> | ||
| + | **[[6lgw]] – rmscFv + rabies glycoprotein<br /> | ||
| + | |||
| + | * Single chain variable fragment complex with small molecule | ||
| + | |||
| + | **[[5i4f]], [[5vf2]] – mscFv + mannobiose<br /> | ||
| + | **[[4h0i]] – mscFv + mannopyranoside<br /> | ||
| + | **[[2cju]] – mscFv + phOxGABA<br /> | ||
| + | **[[2uud]] – mscFv + hapten<br /> | ||
| + | **[[5j74]], [[5j75]] – hscFv + inhibitor<br /> | ||
| + | **[[4lar]] – hscFv + dexedrine<br /> | ||
| + | **[[4las]] – hscFv + amphetamine derivative<br /> | ||
| + | **[[6k4z]] – mscFv + NPA<br /> | ||
| + | |||
| + | * Single chain variable fragment complex with peptide | ||
| + | |||
| + | **[[5yax]] – hscFv + HBV peptide<br /> | ||
| + | **[[5a2i]], [[5aij]], [[5a2k]], [[5a2l]] – mscFv + TN peptide<br /> | ||
| + | **[[1p4b]] – mscFv + GCN4 peptide<br /> | ||
| + | **[[4h0h]], [[5fxc]], [[5owp]], [[1ktr]], [[6fzq]], [[6tgg]] – mscFv + peptide<br /> | ||
| + | |||
| + | *Single domain antibody VHH or Camelid antibody or nanobody or single domain antibody or sybody | ||
| + | |||
| + | **[[5i0z]], [[5c6w]] – hVHH <br /> | ||
| + | **[[6cnw]] – hyVHH - hybrid<br /> | ||
| + | **[[4ppt]], [[4idl]], [[1shm]], [[2xa3]], [[5sv4]], [[4w81]], [[4w70]], [[4w68]], [[4tyu]], [[6ezw]], [[6f0d]], [[5nlu]], [[4krn]], [[4poy]], [[1sjv]], [[1u0q]], [[3qxu]], [[3qxw]], [[4b50]], [[5tp3]], [[1sjx]], [[4qgy]], [[5h8d]], [[4b5e]], [[6dbd]], [[6fpv]], [[6fys]], [[6oc8]], [[6ru3]], [[7lvu]] – LgVHH <br /> | ||
| + | **[[1g9e]], [[7eh3]] – LgVHH - NMR<br /> | ||
| + | **[[4u05]] – LgVHH (mutant)<br /> | ||
| + | **[[4w2p]], [[6apo]], [[6app]], [[6apq]] – LgVHH anti-marburg virus<br /> | ||
| + | **[[6ck8]] – LgVHH anti-influenza virus<br /> | ||
| + | **[[6cwk]] – ViVHH anti-ricin<br /> | ||
| + | **[[6dyx]], [[6iyn]] – ViVHH <br /> | ||
| + | **[[5u64]], [[5u65]], [[1f2x]], [[1yc7]], [[5e7b]], [[5m7q]], [[5jmr]], [[3dwt]], [[3tpk]], [[3ln9]], [[6heq]], [[6jb9]], [[6qtl]] – cVHH <br /> | ||
| + | **[[1yc8]], [[3eak]] – cVHH (mutant)<br /> | ||
| + | **[[6itp]], [[6itq]] – cVHH anti-cortisol<br /> | ||
| + | **[[6t2j]], [[7mfv]] – syVHH <br /> | ||
| + | **[[7v0v]] – syVHH anti-GFP - NMR<br /> | ||
| + | |||
| + | *VHH binary complexes | ||
| + | |||
| + | **[[6oan]], [[6oao]] – hVHH + DBP<br /> | ||
| + | **[[6sge]] – hVHH + ROHB<br /> | ||
| + | **[[7ssz]] - hVHH + Kv1.3 – Cryo EM<br /> | ||
| + | **[[1i3u]], [[1i3v]], [[1dq0]] - LgVHH + hapten<br /> | ||
| + | **[[3qxt]], [[3qxv]] – LgVHH + methotrexate<br /> | ||
| + | **[[4pou]], [[1bzq]] – LgVHH + RNAse 1<br /> | ||
| + | **[[4nc1]], [[4nbx]], [[4nby]], [[4nbz]], [[4nc0]], [[4nc2]] – LgVHH + TcdA<br /> | ||
| + | **[[3k81]], [[3stb]], [[4dk3]], [[4dk6]], [[4dka]], [[3k7u]], [[3k80]] – LgVHH + RNA editing complex protein<br /> | ||
| + | **[[5tok]], [[5toj]] – LgVHH + F glycoprotein<br /> | ||
| + | **[[5boz]], [[5j57]], [[5j56]], [[5e1h]], [[5sv3]], [[7kbi]], [[7kbk]], [[7kc9]], [[7kd0]], [[7kd2]], [[7kdm]], [[7kdu]] – LgVHH + ricin<br /> | ||
| + | **[[5hm1]] – LgVHH + gp41<br /> | ||
| + | **[[5o2u]] – LgVHH + p24<br /> | ||
| + | **[[4grw]] – LgVHH + IL-23<br /> | ||
| + | **[[5nqw]] – LgVHH + IGE-FC<br /> | ||
| + | **[[4hep]], [[4hem]] – LgVHH + BPP<br /> | ||
| + | **[[4w2q]], [[4w2o]], [[6app]] – LgVHH + Marburg virus nucleoprotein<br /> | ||
| + | **[[6fyt]], [[6fyu]], [[6fyw]], [[6s0y]] – LgVHH + Influenza virus protein<br /> | ||
| + | **[[6qx3]] – LgVHH + Influenza virus protein – Cryo EM<br /> | ||
| + | **[[7dst]] – LgVHH + FMDV proteins – Cryo EM<br /> | ||
| + | **[[7jkm]] – LgVHH + hFab<br /> | ||
| + | **[[6ana]], [[6and]], [[6ani]] – LgVHH + mFab<br /> | ||
| + | **[[4krl]], [[4krm]] – LgVHH + EGFR<br /> | ||
| + | **[[2bse]] – LgVHH + receptor-binding protein<br /> | ||
| + | **[[4ej1]], [[4eiz]], [[4eig]] – LgVHH + DHFR <br /> | ||
| + | **[[3p0g]], [[4lde]], [[4ldl]], [[4ldo]], [[6mxt]], [[7bu7]] – LgVHH + adrenergic receptor<br /> | ||
| + | **[[4n1h]], [[4m3k]], [[5lwf]] – LgVHH + beta-lactamase<br /> | ||
| + | **[[5m94]], [[5m95]] – LgVHH + metal cation transporter<br /> | ||
| + | **[[5h8o]], [[6f2g]] – LgVHH + ASC<br /> | ||
| + | **[[3k3q]] – LgVHH + Botox<br /> | ||
| + | **[[4wem]], [[4wen]], [[4weu]] – LgVHH + adhesin<br /> | ||
| + | **[[4p2c]] – LgVHH + Shiga toxin<br /> | ||
| + | **[[6oq5]], [[6oq6]], [[6oq7]], [[6oq8]] – LgVHH + Clostridium toxin<br /> | ||
| + | **[[6hjx]], [[6ssi]] – LgVHH + ELIC<br /> | ||
| + | **[[4aq1]] – LgVHH + SBSB<br /> | ||
| + | **[[6h7j]], [[6h7l]], [[6h7m]], [[6h7n]] – lgVHH + thioredoxin + adrenergic receptor <br /> | ||
| + | **[[6u51]], [[6u52]], [[6u54]], [[6u55]] – LgVHH anti-ebola + nucleoprotein<br /> | ||
| + | **[[7lvw]] – LgVHH + RSV fusion protein<br /> | ||
| + | **[[6qup]] – LgVHH + receptor kinase<br /> | ||
| + | **[[6qgy]] – LgVHH + BamA<br /> | ||
| + | **[[6rvc]] – LgVHH + PTCH1<br /> | ||
| + | **[[6z6v]] – LgVHH + complement C1<br /> | ||
| + | **[[7qiv]] – LgVHH + complement C3b<br /> | ||
| + | **[[6h15]] – LgVHH + LRP6<br /> | ||
| + | **[[6b73]] – LgVHH + opioid receptor<br /> | ||
| + | **[[6i8g]] – LgVHH + EDS1<br /> | ||
| + | **[[6hhu]] – LgVHH + SAP<br /> | ||
| + | **[[6c9w]] – LgVHH + lactose permease<br /> | ||
| + | **[[6h02]] – LgVHH + mediator of RNA polymerase<br /> | ||
| + | **[[6gs4]] – LgVHH + DtpA<br /> | ||
| + | **[[6z1v]] – LgVHH + CD9<br /> | ||
| + | **[[7anq]] - LgVHH + PCSK9 <br /> | ||
| + | **[[7d4b]] - LgVHH + TNFRSF9 <br /> | ||
| + | **[[7nmu]] - LgVHH + platelet glycoprotein<br /> | ||
| + | **[[7a6o]] - LgVHH + von willenbrand factor <br /> | ||
| + | **[[7a48]], [[7a4d]], [[7a4t]], [[7a4y]], [[7a50]] - LgVHH + coiled-coil <br /> | ||
| + | **[[7qcq]] - LgVHH + Tau peptide <br /> | ||
| + | **[[7jjo]] - LgVHH + Gi proteins + transducin + adrenergic receptor<br /> | ||
| + | **[[7sai]] – LgVHH + GFP<br /> | ||
| + | **[[7a17]] – LgVHH + synaptojanin<br /> | ||
| + | **[[7ckz]] – LgVHH + Gi proteins + dopamine receptor – Cryo EM<br /> | ||
| + | **[[4tvs]] – viVHH + LAP1<br /> | ||
| + | **[[4yga]] – ViVHH + CDPK1<br /> | ||
| + | **[[5l21]] – ViVHH + Botox<br /> | ||
| + | **[[5o04]], [[5o02]], [[5o03]], [[5o05]], [[5tjw]], [[5omn]], [[4x7c]], [[4x7d]], [[4x7e]], [[4x7f]], [[5m30]], [[6h6y]], [[6h71]], [[6h72]], [[6xw4]], [[6xw5]], [[6xw6]] – ViVHH + virus capsid<br /> | ||
| + | **[[2xv6]] – ViVHH + p24<br /> | ||
| + | **[[5hvf]], [[5hvg]], [[5hvh]] – ViVHH + carboxypeptidase<br /> | ||
| + | **[[5hgg]], [[5lhr]], [[5lhq]], [[5lhp]], [[5lhn]] – ViVHH + urokinase-type plasminogen activator <br /> | ||
| + | **[[6gwn]], [[6gwp]], [[7aqg]] – ViVHH + plasminogen activator inhibitor<br /> | ||
| + | **[[5vxm]], [[5vxj]], [[5vxk]], [[5vxl]], [[5vlj]] - ViVHH + invasion IpaD<br /> | ||
| + | **[[5u4l]], [[4z9k]], [[4lhj]], [[4lgp]], [[6cwg]], [[5u4m]], [[6obc]], [[6obe]], [[6obg]], [[6obm]], [[6obo]], [[6oca]], [[6ocd]] – ViVHH anti-ricin + ricin<br /> | ||
| + | **[[6x06]], [[6x07]], [[6x08]], [[7nqa]] – ViVHH + nucleoporin<br /> | ||
| + | **[[6rah]], [[6rai]] – ViVHH + TmrAB<br /> | ||
| + | **[[7k7y]], [[7lzp]] – ViVHH + botulinum neurotoxin<br /> | ||
| + | **[[1jto]], [[1jtp]], [[1jtt]], [[1ri8]], [[1xfp]], [[1zmy]], [[1zv5]], [[1zvh]], [[4i0c]], [[1op9]], [[1mel]], [[1rjc]], [[1zvy]], [[6jb8]] – cVHH + lysozyme<br /> | ||
| + | **[[6jb2]], [[6jb5]] – cVHH (mutant) + lysozyme<br /> | ||
| + | **[[2x89]] – cVHH + β-2-microglobulin<br /> | ||
| + | **[[1kxq]], [[1kxt]], [[1kxv]] – cVHH + α-amylase<br /> | ||
| + | **[[3qsk]], [[2p42]], [[2p43]], [[2p44]], [[2p45]], [[2p46]], [[2p47]], [[2p48]], [[2p49]], [[2p4a]] – cVHH + RNAse 1<br /> | ||
| + | **[[6ir1]], [[6ir2]], [[7sal]] – cVHH + mCherry<br /> | ||
| + | **[[6lr7]] – cVHH + GFP<br /> | ||
| + | **[[6rpj]] – cVHH + CTLA<br /> | ||
| + | **[[6hhd]] – cVHH + major prion protein<br /> | ||
| + | **[[6knm]] - cVHH + apelin receptor<br /> | ||
| + | **[[6sc5]], [[6sc6]], [[6sc7]], [[6sc8]], [[6sc9]] – syVHH + RNF31<br/> | ||
| + | **[[7cz0]] – syVHH + TGP<br/> | ||
| + | |||
| + | *VHH ternary complexes | ||
| + | |||
| + | **[[3v0a]] – LgVHH + BONT/A1 + NTNH<br /> | ||
| + | **[[3sn6]] – LgVHH + adrenergic receptor + guanine nucleotide-binding protein<br /> | ||
| + | **[[7bts]], [[7bu6]] – LgVHH + adrenergic receptor + epinephrine<br /> | ||
| + | **[[6oya]] - LgVHH + guanine nucleotide-binding protein + transducin + rhodopsin + GT-alpha/GI1-alpha – Cryo EM<br /> | ||
| + | **[[4laj]] - LgVHH + envelope glycoprotein gp120 + CD4<br /> | ||
| + | **[[4orz]] – LgVHH + tyrosine protein kinase HCK + NEF<br /> | ||
| + | **[[6v7z]] – LgVHH + CD1d + b-2-microglobulin<br /> | ||
| + | **[[6v80]] – LgVHH + CD1d + NKT TCR + b-2-microglobulin<br /> | ||
| + | **[[4kro]], [[4krp]] – LgVHH + antibody + EGFR<br /> | ||
| + | **[[7q6c]] – LgVHH + complement C1 + antibody<br /> | ||
| + | **[[5j1s]], [[5j1t]] – ViVHH + Torsin + LULL1<br /> | ||
| + | **[[5uk4]], [[5ukb]] – ViVHH + virus capsid + RNA<br /> | ||
| + | **[[5jmo]] – cVHH + furin + CMK inhibitor<br /> | ||
| + | **[[5fuc]] – cVHH + IL-6 + IL-6R <br /> | ||
| + | **[[6h7j]], [[6h7l]], [[6h7m]], [[6h7o]], [[6ibl]] – cVHH + thioredoxin + adrenergic receptor<br /> | ||
| + | **[[6n48]] – cVHH + modulator + adrenergic receptor<br /> | ||
| + | **[[6do1]] – syVHH + BRIL + S1I8 peptide<br/> | ||
| + | |||
| + | *Intrabody or anti-helix antibody | ||
| + | |||
| + | **[[6k67]] – hIB 3LRH + calmodulin<br /> | ||
| + | **[[6k3m]], [[6k64]], [[6k6a]], [[6k6b]] – hIB 3LRH + SpA IgG-binding domain protein<br /> | ||
| + | **[[6k69]] – hIB 3LRH + T4 lysozyme<br /> | ||
| + | |||
| + | *Diabody or single chain Fv | ||
| + | |||
| + | **[[5fcs]], [[5grv]], [[5grw]], [[5grx]], [[5gry]], [[5grz]], [[5gs1]] – hDiab<br /> | ||
| + | **[[4y5v]], [[4y5x]], [[4y5y]] – hDiab + EpoR<br /> | ||
| + | **[[5gru]] – hDiab + MBP<br /> | ||
| + | **[[5gs0]] – hDiab + TLR3<br /> | ||
| + | **[[6vug]] – hDiab + Hiv reverse transcriptase + DNA<br /> | ||
| + | |||
| + | *Antibody VH domain (residues 1-121) | ||
| + | |||
| + | **[[1t2j]], [[3b9v]], [[3qyc]], [[7omn]], [[7ooi]] – hVH <br /> | ||
| + | **[[1vhp]] – hVH - NMR<br /> | ||
| + | **[[7d6y]], [[7d8b]], [[7f07]], [[7xtp]] – hVH + EIF4E<br /> | ||
| + | **[[4u3x]] – hVH + lysozyme<br /> | ||
| + | **[[7dv4]] – hVH + CTLA-4<br /> | ||
| + | **[[5fv2]] – hVH + VEGF<br /> | ||
| + | **[[8di5]] – hVH + SARS spike glycoprotein – Cryo EM<br /> | ||
| + | **[[1nqb]] – mVH <br /> | ||
| + | **[[4qgy]], [[4qlr]] – LgVH <br /> | ||
| + | |||
}} | }} | ||
| + | [[Category: Topic Page]] | ||
Current revision
Humanized mouse antibody (hmFab) is a modified mFab which resembles more hFab.
Broadly neutralizing Fab and Neutralizing Fab are anti-HIV Fab.
Lama antibodies or nanobodies or camelid or VHH are natural single-domain antibodies containing just the heavy chain.
scFv is a single chain variable fragment in a fusion protein of the variable regions of the heavy and light chains of immunoglobulin.
3D structures of Antibody
Updated on 11-March-2023
