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5iwd

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==HCMV DNA polymerase subunit UL44 complex with a small molecule==
==HCMV DNA polymerase subunit UL44 complex with a small molecule==
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<StructureSection load='5iwd' size='340' side='right' caption='[[5iwd]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
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<StructureSection load='5iwd' size='340' side='right'caption='[[5iwd]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5iwd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IWD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IWD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5iwd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_herpesvirus_5_strain_AD169 Human herpesvirus 5 strain AD169]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IWD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IWD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6EV:5-METHYLIDENE-3-(METHYLSULFANYL)-2-BENZOTHIOPHEN-4(5H)-ONE'>6EV</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.56&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yyp|1yyp]], [[1t6l|1t6l]], [[5ixa|5ixa]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6EV:5-METHYLIDENE-3-(METHYLSULFANYL)-2-BENZOTHIOPHEN-4(5H)-ONE'>6EV</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iwd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iwd OCA], [http://pdbe.org/5iwd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iwd RCSB], [http://www.ebi.ac.uk/pdbsum/5iwd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iwd ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5iwd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iwd OCA], [https://pdbe.org/5iwd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5iwd RCSB], [https://www.ebi.ac.uk/pdbsum/5iwd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5iwd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/VPAP_HCMVA VPAP_HCMVA]] Accessory subunit of the DNA polymerase that acts to increase the processivity of polymerization.<ref>PMID:20538862</ref>
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[https://www.uniprot.org/uniprot/VPAP_HCMVA VPAP_HCMVA] Accessory subunit of the DNA polymerase that acts to increase the processivity of polymerization.<ref>PMID:20538862</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chen, H]]
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[[Category: Human herpesvirus 5 strain AD169]]
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[[Category: Coen, D M]]
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[[Category: Large Structures]]
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[[Category: Filman, D J]]
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[[Category: Chen H]]
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[[Category: Hogle, J M]]
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[[Category: Coen DM]]
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[[Category: Covalent inhibitor]]
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[[Category: Filman DJ]]
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[[Category: Dna polymerase]]
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[[Category: Hogle JM]]
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[[Category: Hcmv pol accessory subunit]]
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[[Category: Human cytomegalovirus]]
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[[Category: Processivity factor]]
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[[Category: Protein-protein interaction]]
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[[Category: Replication-replication inhibitor complex]]
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Current revision

HCMV DNA polymerase subunit UL44 complex with a small molecule

PDB ID 5iwd

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