5ho4

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==Crystal structure of hnRNPA2B1 in omplex with 10-mer RNA==
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==Crystal structure of hnRNPA2B1 in complex with 10-mer RNA==
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<StructureSection load='5ho4' size='340' side='right' caption='[[5ho4]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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<StructureSection load='5ho4' size='340' side='right'caption='[[5ho4]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ho4]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HO4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HO4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ho4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HO4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HO4 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ho4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ho4 OCA], [http://pdbe.org/5ho4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ho4 RCSB], [http://www.ebi.ac.uk/pdbsum/5ho4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ho4 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ho4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ho4 OCA], [https://pdbe.org/5ho4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ho4 RCSB], [https://www.ebi.ac.uk/pdbsum/5ho4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ho4 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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[[http://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN]] Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref>
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[https://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN] Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN]] Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus.
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[https://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN] Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus.
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Gan, J H]]
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[[Category: Homo sapiens]]
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[[Category: Ma, J B]]
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[[Category: Large Structures]]
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[[Category: Su, S C]]
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[[Category: Synthetic construct]]
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[[Category: Wu, B X]]
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[[Category: Gan JH]]
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[[Category: Hnrnpa2b1]]
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[[Category: Ma JB]]
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[[Category: Rna binding protein-rna complex]]
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[[Category: Su SC]]
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[[Category: Rrm]]
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[[Category: Wu BX]]

Current revision

Crystal structure of hnRNPA2B1 in complex with 10-mer RNA

PDB ID 5ho4

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