5f71
From Proteopedia
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==Human T-cell immunoglobulin and mucin domain protein 3 (hTIM-3)== | ==Human T-cell immunoglobulin and mucin domain protein 3 (hTIM-3)== | ||
| - | <StructureSection load='5f71' size='340' side='right' caption='[[5f71]], [[Resolution|resolution]] 2.40Å' scene=''> | + | <StructureSection load='5f71' size='340' side='right'caption='[[5f71]], [[Resolution|resolution]] 2.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5f71]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F71 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5f71]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F71 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5F71 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.404Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5f71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f71 OCA], [https://pdbe.org/5f71 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5f71 RCSB], [https://www.ebi.ac.uk/pdbsum/5f71 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5f71 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/HAVR2_HUMAN HAVR2_HUMAN] Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.<ref>PMID:14556005</ref> <ref>PMID:16286920</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Gao GF]] |
| - | [[Category: | + | [[Category: Lu G]] |
| - | [[Category: | + | [[Category: Qi J]] |
| - | [[Category: | + | [[Category: Wang H]] |
| - | + | ||
| - | + | ||
Current revision
Human T-cell immunoglobulin and mucin domain protein 3 (hTIM-3)
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Categories: Homo sapiens | Large Structures | Gao GF | Lu G | Qi J | Wang H
