5kjz

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'''Unreleased structure'''
 
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The entry 5kjz is ON HOLD until Paper Publication
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==Co-crystal structure of PKA RI alpha CNB-B mutant (G316R/A336T) with cGMP==
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<StructureSection load='5kjz' size='340' side='right'caption='[[5kjz]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5kjz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KJZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KJZ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.347&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PCG:CYCLIC+GUANOSINE+MONOPHOSPHATE'>PCG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5kjz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kjz OCA], [https://pdbe.org/5kjz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5kjz RCSB], [https://www.ebi.ac.uk/pdbsum/5kjz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5kjz ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/KAP0_HUMAN KAP0_HUMAN] Acute promyelocytic leukemia;Acrodysostosis with multiple hormone resistance;Familial atrial myxoma;Primary pigmented nodular adrenocortical disease;Carney complex;Acrodysostosis. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/KAP0_HUMAN KAP0_HUMAN] Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.<ref>PMID:16491121</ref> <ref>PMID:20215566</ref> <ref>PMID:26405036</ref>
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Authors: Lorenz, R., Moon, E.W., Kim, J.J., Huang, G.Y., Kim, C., Herberg, F.W.
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==See Also==
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*[[CAMP-dependent protein kinase 3D structures|CAMP-dependent protein kinase 3D structures]]
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Description: Co-crystal structure of PKG RI alpha CNB-B mutant (G316R/A336T) with cGMP
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== References ==
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[[Category: Unreleased Structures]]
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<references/>
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[[Category: Kim, C]]
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__TOC__
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[[Category: Kim, J.J]]
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</StructureSection>
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[[Category: Lorenz, R]]
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[[Category: Homo sapiens]]
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[[Category: Huang, G.Y]]
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[[Category: Large Structures]]
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[[Category: Moon, E.W]]
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[[Category: Herberg FW]]
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[[Category: Herberg, F.W]]
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[[Category: Huang GY]]
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[[Category: Kim C]]
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[[Category: Kim JJ]]
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[[Category: Lorenz R]]
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[[Category: Moon E]]

Current revision

Co-crystal structure of PKA RI alpha CNB-B mutant (G316R/A336T) with cGMP

PDB ID 5kjz

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