5knr
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==E. coli HPRT in complexed with 9-[(N-phosphonoethyl-N-phosphonoethoxyethyl)-2-aminoethyl]-guanine== | |
| + | <StructureSection load='5knr' size='340' side='right'caption='[[5knr]], [[Resolution|resolution]] 2.86Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5knr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KNR FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.864Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3L5:(2-{[2-(2-AMINO-6-OXO-3,6-DIHYDRO-9H-PURIN-9-YL)ETHYL][2-(2-PHOSPHONOETHOXY)ETHYL]AMINO}ETHYL)PHOSPHONIC+ACID'>3L5</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5knr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knr OCA], [https://pdbe.org/5knr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5knr RCSB], [https://www.ebi.ac.uk/pdbsum/5knr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5knr ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HPRT_ECOLI HPRT_ECOLI] Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine. | ||
| - | + | ==See Also== | |
| - | + | *[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Escherichia coli]] |
| - | [[Category: Eng | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Eng WS]] |
| - | [[Category: Janeba | + | [[Category: Hockova D]] |
| + | [[Category: Janeba Z]] | ||
| + | [[Category: Keough DT]] | ||
Current revision
E. coli HPRT in complexed with 9-[(N-phosphonoethyl-N-phosphonoethoxyethyl)-2-aminoethyl]-guanine
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