5lug

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'''Unreleased structure'''
 
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The entry 5lug is ON HOLD
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==Crystal structure of human Spindlin-2B protein in complex with ART(M3L)QTA(2MR)KS peptide==
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<StructureSection load='5lug' size='340' side='right'caption='[[5lug]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5lug]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LUG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LUG FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lug OCA], [https://pdbe.org/5lug PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lug RCSB], [https://www.ebi.ac.uk/pdbsum/5lug PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lug ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SPI2B_HUMAN SPI2B_HUMAN] Involved in the regulation of cell cycle progression, this activity is related to the inhibition of apoptosis following the removal of essential growth factors (PubMed:12145692). Exhibits H3K4me3-binding activity (PubMed:29061846).<ref>PMID:12145692</ref> <ref>PMID:29061846</ref>
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Authors: Srikannathasan, V., Gileadi, C., Talon, R., Shrestha, L., Kopec, J., Szykowska, A., Burgess-Brown, N., Arrowsmith, C.H., Edwards, A.M., Bountra, C., von Delft, F., Oppermann, U., Huber, K.
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==See Also==
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*[[Spindlin|Spindlin]]
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Description: Crystal structure of human Spindlin-2B protein in complex with ART(M3L)QTA(2MR)KS peptide
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== References ==
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[[Category: Unreleased Structures]]
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<references/>
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[[Category: Huber, K]]
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__TOC__
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[[Category: Arrowsmith, C.H]]
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</StructureSection>
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[[Category: Burgess-Brown, N]]
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[[Category: Homo sapiens]]
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[[Category: Shrestha, L]]
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[[Category: Large Structures]]
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[[Category: Gileadi, C]]
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[[Category: Arrowsmith CH]]
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[[Category: Oppermann, U]]
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[[Category: Bountra C]]
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[[Category: Szykowska, A]]
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[[Category: Burgess-Brown N]]
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[[Category: Kopec, J]]
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[[Category: Edwards AM]]
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[[Category: Von Delft, F]]
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[[Category: Gileadi C]]
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[[Category: Edwards, A.M]]
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[[Category: Huber K]]
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[[Category: Talon, R]]
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[[Category: Kopec J]]
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[[Category: Srikannathasan, V]]
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[[Category: Oppermann U]]
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[[Category: Bountra, C]]
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[[Category: Shrestha L]]
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[[Category: Srikannathasan V]]
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[[Category: Szykowska A]]
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[[Category: Talon R]]
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[[Category: Von Delft F]]

Current revision

Crystal structure of human Spindlin-2B protein in complex with ART(M3L)QTA(2MR)KS peptide

PDB ID 5lug

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OCA

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