1sow

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[[Image:1sow.gif|left|200px]]
 
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{{Structure
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==T. gondii bradyzoite-specific LDH (LDH2) in complex with NAD and oxalate==
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|PDB= 1sow |SIZE=350|CAPTION= <scene name='initialview01'>1sow</scene>, resolution 1.9&Aring;
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<StructureSection load='1sow' size='340' side='right'caption='[[1sow]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene>
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<table><tr><td colspan='2'>[[1sow]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SOW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SOW FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sow OCA], [https://pdbe.org/1sow PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sow RCSB], [https://www.ebi.ac.uk/pdbsum/1sow PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sow ProSAT]</span></td></tr>
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|RELATEDENTRY=[[1sov|1SOV]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sow OCA], [http://www.ebi.ac.uk/pdbsum/1sow PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1sow RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/LDH_TOXGO LDH_TOXGO]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/so/1sow_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sow ConSurf].
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<div style="clear:both"></div>
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'''T. gondii bradyzoite-specific LDH (LDH2) in complex with NAD and oxalate'''
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==See Also==
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*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1SOW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SOW OCA].
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[[Category: Large Structures]]
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[[Category: L-lactate dehydrogenase]]
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[[Category: Single protein]]
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[[Category: Toxoplasma gondii]]
[[Category: Toxoplasma gondii]]
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[[Category: Kavanagh, K L.]]
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[[Category: Kavanagh KL]]
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[[Category: Wilson, D K.]]
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[[Category: Wilson DK]]
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[[Category: nad-binding]]
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[[Category: rossmann fold]]
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[[Category: tetramer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:45:03 2008''
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Current revision

T. gondii bradyzoite-specific LDH (LDH2) in complex with NAD and oxalate

PDB ID 1sow

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