5pmt
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5pmt is ON HOLD Authors: Krojer, T. Description: PanDDA analysis group deposition --Crystal Structure of JMJD2D after initial refinement with no li...) |
|||
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==PanDDA analysis group deposition -- Crystal Structure of JMJD2D after initial refinement with no ligand modelled (structure 187)== | |
| + | <StructureSection load='5pmt' size='340' side='right'caption='[[5pmt]], [[Resolution|resolution]] 1.22Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5pmt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5PMT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5PMT FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.22Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5pmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5pmt OCA], [https://pdbe.org/5pmt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5pmt RCSB], [https://www.ebi.ac.uk/pdbsum/5pmt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5pmt ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KDM4D_HUMAN KDM4D_HUMAN] Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.<ref>PMID:16603238</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Jumonji domain-containing protein 3D structures|Jumonji domain-containing protein 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Krojer | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Bradley AR]] | ||
| + | [[Category: Brandao-Neto J]] | ||
| + | [[Category: Brennan PE]] | ||
| + | [[Category: Burgess-Brown N]] | ||
| + | [[Category: Collins P]] | ||
| + | [[Category: Cox O]] | ||
| + | [[Category: Dias A]] | ||
| + | [[Category: Douangamath A]] | ||
| + | [[Category: Edwards A]] | ||
| + | [[Category: Fairhead M]] | ||
| + | [[Category: Krojer T]] | ||
| + | [[Category: MacLean E]] | ||
| + | [[Category: Ng J]] | ||
| + | [[Category: Oppermann U]] | ||
| + | [[Category: Pearce NM]] | ||
| + | [[Category: Renjie Z]] | ||
| + | [[Category: Sethi R]] | ||
| + | [[Category: Szykowska A]] | ||
| + | [[Category: Talon R]] | ||
| + | [[Category: Vollmar M]] | ||
| + | [[Category: Wright N]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
PanDDA analysis group deposition -- Crystal Structure of JMJD2D after initial refinement with no ligand modelled (structure 187)
| |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Bradley AR | Brandao-Neto J | Brennan PE | Burgess-Brown N | Collins P | Cox O | Dias A | Douangamath A | Edwards A | Fairhead M | Krojer T | MacLean E | Ng J | Oppermann U | Pearce NM | Renjie Z | Sethi R | Szykowska A | Talon R | Vollmar M | Wright N | Von Delft F
