5txr
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of ALAS from S. cerevisiae non-covalently bound to PLP cofactor== | |
| - | + | <StructureSection load='5txr' size='340' side='right'caption='[[5txr]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5txr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TXR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TXR FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5txr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5txr OCA], [https://pdbe.org/5txr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5txr RCSB], [https://www.ebi.ac.uk/pdbsum/5txr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5txr ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Brown | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/HEM1_YEAST HEM1_YEAST] Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.<ref>PMID:6381051</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Baker TA]] | ||
| + | [[Category: Brown BL]] | ||
| + | [[Category: Grant RA]] | ||
| + | [[Category: Kardon JR]] | ||
| + | [[Category: Sauer RT]] | ||
Current revision
Structure of ALAS from S. cerevisiae non-covalently bound to PLP cofactor
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