1szy

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[[Image:1szy.gif|left|200px]]
 
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{{Structure
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==Solution structure of ITALY1 ("Initiator tRNA Anticodon Loop from Yeast"), an unmodified 21-nt RNA with the sequence of the anticodon stem-loop of yeast initiator tRNA==
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|PDB= 1szy |SIZE=350|CAPTION= <scene name='initialview01'>1szy</scene>
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<StructureSection load='1szy' size='340' side='right'caption='[[1szy]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
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<table><tr><td colspan='2'>[[1szy]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SZY FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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|GENE=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1szy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1szy OCA], [https://pdbe.org/1szy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1szy RCSB], [https://www.ebi.ac.uk/pdbsum/1szy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1szy ProSAT]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=
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<div style="background-color:#fffaf0;">
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1szy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1szy OCA], [http://www.ebi.ac.uk/pdbsum/1szy PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1szy RCSB]</span>
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== Publication Abstract from PubMed ==
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}}
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'''Solution structure of ITALY1 ("Initiator tRNA Anticodon Loop from Yeast"), an unmodified 21-nt RNA with the sequence of the anticodon stem-loop of yeast initiator tRNA'''
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==Overview==
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The solution conformations of analogues of initiator and elongator tRNA anticodon stem-loops have been compared by NMR. The data indicate that both have conformations closely similar to those reported for crystalline elongator tRNAs. The two loops differ in their dynamics, however: that of the elongator analogue is more flexible than its initiator counterpart. The anticodon stem-loops of initiator tRNAs are more likely to be distinguished from those of elongator tRNAs during initiation on the basis of their distinctive stem sequences, than they are by differences in the conformations of their anticodon loops.
The solution conformations of analogues of initiator and elongator tRNA anticodon stem-loops have been compared by NMR. The data indicate that both have conformations closely similar to those reported for crystalline elongator tRNAs. The two loops differ in their dynamics, however: that of the elongator analogue is more flexible than its initiator counterpart. The anticodon stem-loops of initiator tRNAs are more likely to be distinguished from those of elongator tRNAs during initiation on the basis of their distinctive stem sequences, than they are by differences in the conformations of their anticodon loops.
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==About this Structure==
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On the conformation of the anticodon loops of initiator and elongator methionine tRNAs.,Schweisguth DC, Moore PB J Mol Biol. 1997 Apr 4;267(3):505-19. PMID:9126834<ref>PMID:9126834</ref>
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1SZY is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZY OCA].
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==Reference==
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On the conformation of the anticodon loops of initiator and elongator methionine tRNAs., Schweisguth DC, Moore PB, J Mol Biol. 1997 Apr 4;267(3):505-19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9126834 9126834]
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[[Category: Protein complex]]
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[[Category: Moore, P B.]]
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[[Category: Schweisguth, D C.]]
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[[Category: initiator trna anticodon loop]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:49:13 2008''
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 1szy" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Moore PB]]
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[[Category: Schweisguth DC]]

Current revision

Solution structure of ITALY1 ("Initiator tRNA Anticodon Loop from Yeast"), an unmodified 21-nt RNA with the sequence of the anticodon stem-loop of yeast initiator tRNA

PDB ID 1szy

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