1t5y

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[[Image:1t5y.gif|left|200px]]
 
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{{Structure
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==Crystal Structure of Northeast Structural Genomics Consortium Target HR2118: A Human Homolog of Saccharomyces cerevisiae Nip7p==
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|PDB= 1t5y |SIZE=350|CAPTION= <scene name='initialview01'>1t5y</scene>, resolution 2.50&Aring;
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<StructureSection load='1t5y' size='340' side='right'caption='[[1t5y]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
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<table><tr><td colspan='2'>[[1t5y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T5Y FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1374 NIP7]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t5y OCA], [https://pdbe.org/1t5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t5y RCSB], [https://www.ebi.ac.uk/pdbsum/1t5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t5y ProSAT], [https://www.topsan.org/Proteins/NESGC/1t5y TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t5y OCA], [http://www.ebi.ac.uk/pdbsum/1t5y PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1t5y RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/NIP7_HUMAN NIP7_HUMAN] Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.<ref>PMID:22195017</ref>
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== Evolutionary Conservation ==
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'''Crystal Structure of Northeast Structural Genomics Consortium Target HR2118: A Human Homolog of Saccharomyces cerevisiae Nip7p'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t5/1t5y_consurf.spt"</scriptWhenChecked>
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1T5Y is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T5Y OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t5y ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Acton, T B.]]
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[[Category: Acton TB]]
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[[Category: Chen, Y.]]
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[[Category: Chen Y]]
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[[Category: Cooper, B.]]
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[[Category: Cooper B]]
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[[Category: Forouhar, F.]]
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[[Category: Forouhar F]]
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[[Category: Hunt, J F.]]
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[[Category: Hunt JF]]
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[[Category: Kuzin, A P.]]
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[[Category: Kuzin AP]]
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[[Category: Ma, L C.]]
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[[Category: Ma L-C]]
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[[Category: Montelione, G.]]
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[[Category: Montelione G]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Shastry R]]
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[[Category: Shastry, R.]]
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[[Category: Tong L]]
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[[Category: Tong, L.]]
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[[Category: Xiao R]]
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[[Category: Xiao, R.]]
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[[Category: nesg]]
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[[Category: northeast structural genomics consortium]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomic]]
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[[Category: unknown function]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:51:42 2008''
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Current revision

Crystal Structure of Northeast Structural Genomics Consortium Target HR2118: A Human Homolog of Saccharomyces cerevisiae Nip7p

PDB ID 1t5y

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