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4d6i

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==Crystal structure of a family 98 glycoside hydrolase catalytic module (Sp3GH98) in complex with the type 1 blood group A-tetrasaccharide (E558A L19 mutant)==
==Crystal structure of a family 98 glycoside hydrolase catalytic module (Sp3GH98) in complex with the type 1 blood group A-tetrasaccharide (E558A L19 mutant)==
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<StructureSection load='4d6i' size='340' side='right' caption='[[4d6i]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
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<StructureSection load='4d6i' size='340' side='right'caption='[[4d6i]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4d6i]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D6I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D6I FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4d6i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_SP3-BS71 Streptococcus pneumoniae SP3-BS71]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D6I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D6I FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4d6c|4d6c]], [[4d6d|4d6d]], [[4d6e|4d6e]], [[4d6f|4d6f]], [[4d6g|4d6g]], [[4d6h|4d6h]], [[4d6j|4d6j]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Blood-group-substance_endo-1,4-beta-galactosidase Blood-group-substance endo-1,4-beta-galactosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.102 3.2.1.102] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d6i OCA], [https://pdbe.org/4d6i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d6i RCSB], [https://www.ebi.ac.uk/pdbsum/4d6i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d6i ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d6i OCA], [http://pdbe.org/4d6i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4d6i RCSB], [http://www.ebi.ac.uk/pdbsum/4d6i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4d6i ProSAT]</span></td></tr>
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</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Blood-group-substance endo-1,4-beta-galactosidase]]
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[[Category: Large Structures]]
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[[Category: Boraston, A B]]
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[[Category: Streptococcus pneumoniae SP3-BS71]]
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[[Category: Chapanian, R]]
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[[Category: Boraston AB]]
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[[Category: Constantinescu, I]]
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[[Category: Chapanian R]]
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[[Category: Higgins, M A]]
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[[Category: Constantinescu I]]
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[[Category: Kizhakkedathu, J N]]
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[[Category: Higgins MA]]
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[[Category: Kwan, D H]]
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[[Category: Kizhakkedathu JN]]
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[[Category: Samain, E]]
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[[Category: Kwan DH]]
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[[Category: Withers, S G]]
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[[Category: Samain E]]
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[[Category: Blood group antigen]]
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[[Category: Withers SG]]
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[[Category: Hydrolase]]
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Current revision

Crystal structure of a family 98 glycoside hydrolase catalytic module (Sp3GH98) in complex with the type 1 blood group A-tetrasaccharide (E558A L19 mutant)

PDB ID 4d6i

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