4wmt

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:33, 27 September 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==STRUCTURE OF MBP-MCL1 BOUND TO ligand 1 AT 2.35A==
==STRUCTURE OF MBP-MCL1 BOUND TO ligand 1 AT 2.35A==
-
<StructureSection load='4wmt' size='340' side='right' caption='[[4wmt]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
+
<StructureSection load='4wmt' size='340' side='right'caption='[[4wmt]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4wmt]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WMT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WMT FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4wmt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WMT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WMT FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=865:7-[2-(1H-IMIDAZOL-1-YL)-4-METHYLPYRIDIN-3-YL]-3-[3-(NAPHTHALEN-1-YLOXY)PROPYL]-1-[2-OXO-2-(PIPERAZIN-1-YL)ETHYL]-1H-INDOLE-2-CARBOXYLIC+ACID'>865</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MAL:MALTOSE'>MAL</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wms|4wms]], [[4wmu|4wmu]], [[4wmv|4wmv]], [[4wmw|4wmw]], [[4wmx|4wmx]], [[4wmr|4wmr]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=865:7-[2-(1H-IMIDAZOL-1-YL)-4-METHYLPYRIDIN-3-YL]-3-[3-(NAPHTHALEN-1-YLOXY)PROPYL]-1-[2-OXO-2-(PIPERAZIN-1-YL)ETHYL]-1H-INDOLE-2-CARBOXYLIC+ACID'>865</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wmt OCA], [http://pdbe.org/4wmt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wmt RCSB], [http://www.ebi.ac.uk/pdbsum/4wmt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wmt ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wmt OCA], [https://pdbe.org/4wmt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wmt RCSB], [https://www.ebi.ac.uk/pdbsum/4wmt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wmt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI]] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.
+
[https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/MCL1_HUMAN MCL1_HUMAN] Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.<ref>PMID:10766760</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 19:
</div>
</div>
<div class="pdbe-citations 4wmt" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4wmt" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[B-cell lymphoma proteins 3D structures|B-cell lymphoma proteins 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Clifton, M C]]
+
[[Category: Escherichia coli K-12]]
-
[[Category: Dranow, D M]]
+
[[Category: Homo sapiens]]
-
[[Category: Apoptosis]]
+
[[Category: Large Structures]]
-
[[Category: Protein-protein interaction]]
+
[[Category: Clifton MC]]
 +
[[Category: Dranow DM]]

Current revision

STRUCTURE OF MBP-MCL1 BOUND TO ligand 1 AT 2.35A

PDB ID 4wmt

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4wmt"
Personal tools