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4xua

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==Crystal Structure of the bromodomain of human BAZ2B in complex with E11919 BAZ2-ICR analogue==
==Crystal Structure of the bromodomain of human BAZ2B in complex with E11919 BAZ2-ICR analogue==
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<StructureSection load='4xua' size='340' side='right' caption='[[4xua]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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<StructureSection load='4xua' size='340' side='right'caption='[[4xua]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4xua]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XUA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4xua]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XUA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=43C:4-{1-[2-(4-METHYL-1H-1,2,3-TRIAZOL-1-YL)ETHYL]-4-PHENYL-1H-IMIDAZOL-5-YL}BENZONITRILE'>43C</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xua OCA], [http://pdbe.org/4xua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xua RCSB], [http://www.ebi.ac.uk/pdbsum/4xua PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xua ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=43C:4-{1-[2-(4-METHYL-1H-1,2,3-TRIAZOL-1-YL)ETHYL]-4-PHENYL-1H-IMIDAZOL-5-YL}BENZONITRILE'>43C</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xua OCA], [https://pdbe.org/4xua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xua RCSB], [https://www.ebi.ac.uk/pdbsum/4xua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xua ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN]] May play a role in transcriptional regulation interacting with ISWI.
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[https://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN] May play a role in transcriptional regulation interacting with ISWI.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4xua" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4xua" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Bromodomain adjacent to zinc finger 3D structures|Bromodomain adjacent to zinc finger 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arrowsmith, C H]]
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[[Category: Homo sapiens]]
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[[Category: Bountra, C]]
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[[Category: Large Structures]]
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[[Category: Chaikuad, A]]
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[[Category: Arrowsmith CH]]
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[[Category: Delft, F von]]
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[[Category: Bountra C]]
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[[Category: Edwards, A M]]
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[[Category: Chaikuad A]]
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[[Category: Felletar, I]]
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[[Category: Edwards AM]]
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[[Category: Knapp, S]]
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[[Category: Felletar I]]
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[[Category: Structural genomic]]
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[[Category: Knapp S]]
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[[Category: Acetylated lysine binding protein]]
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[[Category: Von Delft F]]
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[[Category: Bromodomain]]
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[[Category: Kiaa1476]]
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[[Category: Sgc]]
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[[Category: Transcription]]
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[[Category: Walp4]]
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Current revision

Crystal Structure of the bromodomain of human BAZ2B in complex with E11919 BAZ2-ICR analogue

PDB ID 4xua

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