1t8q

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[[Image:1t8q.jpg|left|200px]]
 
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{{Structure
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==Structural genomics, Crystal structure of Glycerophosphoryl diester phosphodiesterase from E. coli==
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|PDB= 1t8q |SIZE=350|CAPTION= <scene name='initialview01'>1t8q</scene>, resolution 2.00&Aring;
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<StructureSection load='1t8q' size='340' side='right'caption='[[1t8q]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
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<table><tr><td colspan='2'>[[1t8q]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T8Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T8Q FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycerophosphodiester_phosphodiesterase Glycerophosphodiester phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.46 3.1.4.46] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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|GENE= GLPQ, B2239 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam03009 GDPD], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK11143 glpQ]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t8q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t8q OCA], [https://pdbe.org/1t8q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t8q RCSB], [https://www.ebi.ac.uk/pdbsum/1t8q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t8q ProSAT], [https://www.topsan.org/Proteins/MCSG/1t8q TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t8q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t8q OCA], [http://www.ebi.ac.uk/pdbsum/1t8q PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1t8q RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/GLPQ_ECOLI GLPQ_ECOLI] Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t8/1t8q_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t8q ConSurf].
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<div style="clear:both"></div>
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'''Structural genomics, Crystal structure of Glycerophosphoryl diester phosphodiesterase from E. coli'''
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==See Also==
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*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1T8Q is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T8Q OCA].
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Glycerophosphodiester phosphodiesterase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Dementieva I]]
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[[Category: Dementieva, I.]]
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[[Category: Donnelly M]]
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[[Category: Donnelly, M.]]
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[[Category: Duke N]]
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[[Category: Duke, N.]]
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[[Category: Joachimiak A]]
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[[Category: Joachimiak, A.]]
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[[Category: Kim Y]]
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[[Category: Kim, Y.]]
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[[Category: Stols L]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Zhang R]]
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[[Category: Stols, L.]]
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[[Category: Zhang, R.]]
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[[Category: mcsg]]
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[[Category: midwest center for structural genomic]]
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[[Category: phosphodiesterase]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:52:55 2008''
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Current revision

Structural genomics, Crystal structure of Glycerophosphoryl diester phosphodiesterase from E. coli

PDB ID 1t8q

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