This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4mko
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
==Crystal structure of the monomeric, cleaved form of the Pore-Forming Toxin Monalysin== | ==Crystal structure of the monomeric, cleaved form of the Pore-Forming Toxin Monalysin== | ||
| - | <StructureSection load='4mko' size='340' side='right' caption='[[4mko]], [[Resolution|resolution]] 1.70Å' scene=''> | + | <StructureSection load='4mko' size='340' side='right'caption='[[4mko]], [[Resolution|resolution]] 1.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4mko]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MKO OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4mko]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_entomophila_L48 Pseudomonas entomophila L48]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MKO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MKO FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mko OCA], [https://pdbe.org/4mko PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mko RCSB], [https://www.ebi.ac.uk/pdbsum/4mko PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mko ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MONAL_PSEE4 MONAL_PSEE4] Pore-forming toxin that contributes to the virulence of P.entomophila against Drosophila, playing an important role in host intestinal damage and lethality. Displays cytolytic and hemolytic activity.<ref>PMID:21980286</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 21: | Line 23: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Pseudomonas entomophila L48]] |
| - | [[Category: | + | [[Category: Leone P]] |
| - | [[Category: | + | [[Category: Roussel A]] |
Current revision
Crystal structure of the monomeric, cleaved form of the Pore-Forming Toxin Monalysin
| |||||||||||
