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1guz

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==Structural Basis for Thermophilic Protein Stability: Structures of Thermophilic and Mesophilic Malate Dehydrogenases==
==Structural Basis for Thermophilic Protein Stability: Structures of Thermophilic and Mesophilic Malate Dehydrogenases==
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<StructureSection load='1guz' size='340' side='right' caption='[[1guz]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='1guz' size='340' side='right'caption='[[1guz]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1guz]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GUZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1guz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlorobaculum_tepidum Chlorobaculum tepidum] and [https://en.wikipedia.org/wiki/Prosthecochloris_vibrioformis Prosthecochloris vibrioformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GUZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1guy|1guy]], [[1gv0|1gv0]], [[1gv1|1gv1]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1guz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1guz OCA], [https://pdbe.org/1guz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1guz RCSB], [https://www.ebi.ac.uk/pdbsum/1guz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1guz ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1guz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1guz OCA], [http://pdbe.org/1guz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1guz RCSB], [http://www.ebi.ac.uk/pdbsum/1guz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1guz ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MDH_CHLTE MDH_CHLTE]] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_00487]
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[https://www.uniprot.org/uniprot/MDH_CHLTE MDH_CHLTE] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_00487][https://www.uniprot.org/uniprot/MDH_PROVB MDH_PROVB] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_00487]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gu/1guz_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gu/1guz_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Malate dehydrogenase|Malate dehydrogenase]]
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*[[Malate Dehydrogenase 3D structures|Malate Dehydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Malate dehydrogenase]]
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[[Category: Chlorobaculum tepidum]]
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[[Category: Bjork, A]]
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[[Category: Large Structures]]
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[[Category: Dalhus, B]]
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[[Category: Prosthecochloris vibrioformis]]
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[[Category: Eklund, H]]
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[[Category: Bjork A]]
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[[Category: Eklund, P]]
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[[Category: Dalhus B]]
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[[Category: Johansson, K]]
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[[Category: Eklund H]]
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[[Category: Karlsson, A]]
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[[Category: Eklund P]]
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[[Category: Naterstad, K]]
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[[Category: Johansson K]]
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[[Category: Ramaswamy, S]]
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[[Category: Karlsson A]]
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[[Category: Sarinen, M]]
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[[Category: Naterstad K]]
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[[Category: Sauer, U H]]
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[[Category: Ramaswamy S]]
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[[Category: Sirevag, R]]
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[[Category: Sarinen M]]
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[[Category: Synstad, B]]
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[[Category: Sauer UH]]
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[[Category: Dehydrogenase]]
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[[Category: Sirevag R]]
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[[Category: Nad]]
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[[Category: Synstad B]]
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[[Category: Oxidoreductase]]
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[[Category: Tricarboxylic acid cycle]]
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Current revision

Structural Basis for Thermophilic Protein Stability: Structures of Thermophilic and Mesophilic Malate Dehydrogenases

PDB ID 1guz

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