5uxf
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of mouse RECON (AKR1C13) in complex with Cyclic di-AMP== | |
| + | <StructureSection load='5uxf' size='340' side='right'caption='[[5uxf]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5uxf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UXF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UXF FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.501Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2BA:(2R,3R,3AS,5R,7AR,9R,10R,10AS,12R,14AR)-2,9-BIS(6-AMINO-9H-PURIN-9-YL)OCTAHYDRO-2H,7H-DIFURO[3,2-D 3,2-J][1,3,7,9,2,8]TETRAOXADIPHOSPHACYCLODODECINE-3,5,10,12-TETROL+5,12-DIOXIDE'>2BA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5uxf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uxf OCA], [https://pdbe.org/5uxf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5uxf RCSB], [https://www.ebi.ac.uk/pdbsum/5uxf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5uxf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AK1CD_MOUSE AK1CD_MOUSE] Catalyzes the dehydrogenation of 17-beta-hydroxysteroids. May also exhibit significant activity with a variety of cyclic and alicyclic alcohols. Uses both NAD and NADP, but the activity is much greater with NAD than with NADP (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[Aldo-keto reductase 3D structures|Aldo-keto reductase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Luo S]] | ||
| + | [[Category: Tong L]] | ||
Current revision
Crystal Structure of mouse RECON (AKR1C13) in complex with Cyclic di-AMP
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