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1tt4

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[[Image:1tt4.jpg|left|200px]]
 
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{{Structure
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==Structure of NP459575, a predicted glutathione synthase from Salmonella typhimurium==
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|PDB= 1tt4 |SIZE=350|CAPTION= <scene name='initialview01'>1tt4</scene>, resolution 2.801&Aring;
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<StructureSection load='1tt4' size='340' side='right'caption='[[1tt4]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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<table><tr><td colspan='2'>[[1tt4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TT4 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.801&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG2170 COG2170]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tt4 OCA], [https://pdbe.org/1tt4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tt4 RCSB], [https://www.ebi.ac.uk/pdbsum/1tt4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tt4 ProSAT], [https://www.topsan.org/Proteins/MCSG/1tt4 TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tt4 OCA], [http://www.ebi.ac.uk/pdbsum/1tt4 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1tt4 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/GCS2_SALTY GCS2_SALTY] ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.[HAMAP-Rule:MF_01609]
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== Evolutionary Conservation ==
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'''Structure of NP459575, a predicted glutathione synthase from Salmonella typhimurium'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tt/1tt4_consurf.spt"</scriptWhenChecked>
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1TT4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium_lt2 Salmonella typhimurium lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TT4 OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Salmonella typhimurium lt2]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Single protein]]
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</jmolCheckbox>
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[[Category: Anderson, W F.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tt4 ConSurf].
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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<div style="clear:both"></div>
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[[Category: Miller, D J.]]
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__TOC__
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[[Category: Shuvalova, L.]]
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</StructureSection>
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[[Category: glutathione synthase]]
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[[Category: Large Structures]]
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[[Category: mcsg]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: midwest center for structural genomic]]
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[[Category: Anderson WF]]
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[[Category: np459575]]
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[[Category: Miller DJ]]
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[[Category: protein structure initiative]]
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[[Category: Shuvalova L]]
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[[Category: psi]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:00:40 2008''
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Current revision

Structure of NP459575, a predicted glutathione synthase from Salmonella typhimurium

PDB ID 1tt4

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