5flk

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==Structure of haloalkane dehalogenase variant DhaA101==
==Structure of haloalkane dehalogenase variant DhaA101==
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<StructureSection load='5flk' size='340' side='right' caption='[[5flk]], [[Resolution|resolution]] 0.99&Aring;' scene=''>
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<StructureSection load='5flk' size='340' side='right'caption='[[5flk]], [[Resolution|resolution]] 0.99&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5flk]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FLK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FLK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5flk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_rhodochrous Rhodococcus rhodochrous]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FLK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FLK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.99&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Haloalkane_dehalogenase Haloalkane dehalogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.5 3.8.1.5] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5flk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5flk OCA], [http://pdbe.org/5flk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5flk RCSB], [http://www.ebi.ac.uk/pdbsum/5flk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5flk ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5flk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5flk OCA], [https://pdbe.org/5flk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5flk RCSB], [https://www.ebi.ac.uk/pdbsum/5flk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5flk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DHAA_RHORH DHAA_RHORH]] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane.
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[https://www.uniprot.org/uniprot/DHAA_RHORH DHAA_RHORH] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane.
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==See Also==
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*[[Dehalogenase 3D structures|Dehalogenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Haloalkane dehalogenase]]
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[[Category: Large Structures]]
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[[Category: Chaloupkova, R]]
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[[Category: Rhodococcus rhodochrous]]
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[[Category: Damborsky, J]]
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[[Category: Chaloupkova R]]
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[[Category: Waterman, J]]
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[[Category: Damborsky J]]
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[[Category: Alpha/beta-hydrolase]]
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[[Category: Waterman J]]
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[[Category: Hydrolase]]
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Current revision

Structure of haloalkane dehalogenase variant DhaA101

PDB ID 5flk

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