5up6

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#REDIRECT [[6alg]] This PDB entry is obsolete and replaced by 6alg
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==CryoEM structure of HK022 Nun - E.coli RNA polymerase elongation complex==
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<StructureSection load='5up6' size='340' side='right' caption='[[5up6]], [[Resolution|resolution]] 3.74&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5up6]] is a 9 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UP6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UP6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5up6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5up6 OCA], [http://pdbe.org/5up6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5up6 RCSB], [http://www.ebi.ac.uk/pdbsum/5up6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5up6 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RPOC_ECOLI RPOC_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01322] [[http://www.uniprot.org/uniprot/RPOZ_ECOLI RPOZ_ECOLI]] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.[HAMAP-Rule:MF_00366] [[http://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059] [[http://www.uniprot.org/uniprot/RPOB_ECOLI RPOB_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01321]
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__TOC__
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</StructureSection>
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[[Category: DNA-directed RNA polymerase]]
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[[Category: Kang, J Y]]
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[[Category: Seth, D A]]
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[[Category: Bacterial transcription]]
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[[Category: Dna-dependent rna polymerase]]
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[[Category: Ternary elongation complex]]
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[[Category: Transcription arrest]]
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[[Category: Transcription-dna-rna complex]]
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Current revision

  1. REDIRECT 6alg This PDB entry is obsolete and replaced by 6alg

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