1la2

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==Structural analysis of Saccharomyces cerevisiae myo-inositol phosphate synthase==
==Structural analysis of Saccharomyces cerevisiae myo-inositol phosphate synthase==
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<StructureSection load='1la2' size='340' side='right' caption='[[1la2]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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<StructureSection load='1la2' size='340' side='right'caption='[[1la2]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1la2]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LA2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LA2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1la2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LA2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Inositol-3-phosphate_synthase Inositol-3-phosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.5.1.4 5.5.1.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1la2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1la2 OCA], [https://pdbe.org/1la2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1la2 RCSB], [https://www.ebi.ac.uk/pdbsum/1la2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1la2 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1la2 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1la2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1la2 OCA], [http://pdbe.org/1la2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1la2 RCSB], [http://www.ebi.ac.uk/pdbsum/1la2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1la2 ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/1la2 TOPSAN]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/INO1_YEAST INO1_YEAST]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/la/1la2_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/la/1la2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Inositol-3-phosphate synthase]]
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[[Category: Large Structures]]
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[[Category: Beckwith, A]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Buglino, J A]]
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[[Category: Beckwith A]]
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[[Category: Burley, S K]]
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[[Category: Buglino JA]]
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[[Category: Chadna, T]]
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[[Category: Burley SK]]
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[[Category: Kniewel, R]]
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[[Category: Chadna T]]
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[[Category: Lima, C D]]
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[[Category: Kniewel R]]
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[[Category: Structural genomic]]
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[[Category: Lima CD]]
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[[Category: Shen, V]]
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[[Category: Shen V]]
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[[Category: Ino1]]
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[[Category: Inositol]]
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[[Category: Isomerase]]
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[[Category: Metabolism]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Yeast]]
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Current revision

Structural analysis of Saccharomyces cerevisiae myo-inositol phosphate synthase

PDB ID 1la2

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