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5xal
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Y99F mutant of Thermus thermophilus HB8 thymidylate kinase== | |
| + | <StructureSection load='5xal' size='340' side='right'caption='[[5xal]], [[Resolution|resolution]] 1.84Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5xal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XAL FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xal OCA], [https://pdbe.org/5xal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xal RCSB], [https://www.ebi.ac.uk/pdbsum/5xal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xal ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KTHY_THET8 KTHY_THET8] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. | ||
| - | + | ==See Also== | |
| - | + | *[[Thymidylate kinase 3D structures|Thymidylate kinase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Chaudhary | + | [[Category: Large Structures]] |
| - | [[Category: Jeyakanthan | + | [[Category: Thermus thermophilus HB8]] |
| - | [[Category: Sekar | + | [[Category: Chaudhary SK]] |
| + | [[Category: Jeyakanthan J]] | ||
| + | [[Category: Sekar K]] | ||
Current revision
Y99F mutant of Thermus thermophilus HB8 thymidylate kinase
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