5xbf
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal Structure of Myo7b C-terminal MyTH4-FERM in complex with USH1C PDZ3== | |
+ | <StructureSection load='5xbf' size='340' side='right'caption='[[5xbf]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[5xbf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XBF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XBF FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.802Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xbf OCA], [https://pdbe.org/5xbf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xbf RCSB], [https://www.ebi.ac.uk/pdbsum/5xbf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xbf ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/MYO7B_HUMAN MYO7B_HUMAN] Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length. May link the complex to the actin core bundle of microvilli (Probable).<ref>PMID:24725409</ref> <ref>PMID:26812018</ref> | ||
- | + | ==See Also== | |
- | + | *[[Harmonin|Harmonin]] | |
- | + | *[[Myosin 3D Structures|Myosin 3D Structures]] | |
- | [[Category: | + | == References == |
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: He Y]] | ||
+ | [[Category: Li J]] | ||
+ | [[Category: Lu Q]] | ||
+ | [[Category: Tyska MJ]] | ||
+ | [[Category: Weck WL]] | ||
+ | [[Category: Zhang M]] |
Current revision
Crystal Structure of Myo7b C-terminal MyTH4-FERM in complex with USH1C PDZ3
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Categories: Homo sapiens | Large Structures | He Y | Li J | Lu Q | Tyska MJ | Weck WL | Zhang M