1u86

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[[Image:1u86.gif|left|200px]]
 
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{{Structure
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==321-TW-322 insertion mutant of the third zinc finger of BKLF==
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|PDB= 1u86 |SIZE=350|CAPTION= <scene name='initialview01'>1u86</scene>
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<StructureSection load='1u86' size='340' side='right'caption='[[1u86]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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<table><tr><td colspan='2'>[[1u86]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U86 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U86 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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|GENE= BKLF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u86 OCA], [https://pdbe.org/1u86 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u86 RCSB], [https://www.ebi.ac.uk/pdbsum/1u86 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u86 ProSAT]</span></td></tr>
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|RELATEDENTRY=[[1p7a|1P7A]], [[1u85|1U85]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u86 OCA], [http://www.ebi.ac.uk/pdbsum/1u86 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1u86 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/KLF3_MOUSE KLF3_MOUSE] Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis.<ref>PMID:8657145</ref> <ref>PMID:15684403</ref>
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== Evolutionary Conservation ==
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'''321-TW-322 insertion mutant of the third zinc finger of BKLF'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u8/1u86_consurf.spt"</scriptWhenChecked>
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1U86 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U86 OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u86 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Cram ED]]
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[[Category: Cram, E D.]]
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[[Category: Mackay JP]]
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[[Category: Mackay, J P.]]
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[[Category: Matthews JM]]
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[[Category: Matthews, J M.]]
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[[Category: kruppel-like]]
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[[Category: zinc finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:06:41 2008''
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Current revision

321-TW-322 insertion mutant of the third zinc finger of BKLF

PDB ID 1u86

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