5f5o
From Proteopedia
(Difference between revisions)
(5 intermediate revisions not shown.) | |||
Line 1: | Line 1: | ||
- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of Marburg virus nucleoprotein core domain bound to VP35 regulation peptide== | |
+ | <StructureSection load='5f5o' size='340' side='right'caption='[[5f5o]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[5f5o]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Lake_Victoria_marburgvirus_-_Ozolin Lake Victoria marburgvirus - Ozolin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F5O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5F5O FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5f5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f5o OCA], [https://pdbe.org/5f5o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5f5o RCSB], [https://www.ebi.ac.uk/pdbsum/5f5o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5f5o ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/NCAP_MABVO NCAP_MABVO] Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. During replication, encapsidation by NP is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity). | ||
- | + | ==See Also== | |
- | + | *[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]] | |
- | + | __TOC__ | |
- | [[Category: | + | </StructureSection> |
- | [[Category: | + | [[Category: Lake Victoria marburgvirus - Ozolin]] |
- | [[Category: Guo | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Dong SS]] |
- | [[Category: Liu | + | [[Category: Guo Y]] |
- | [[Category: Liu | + | [[Category: Li GB]] |
- | [[Category: | + | [[Category: Liu BC]] |
- | [[Category: Wang | + | [[Category: Liu X]] |
+ | [[Category: Wang WJ]] | ||
+ | [[Category: Wang WM]] |
Current revision
Crystal structure of Marburg virus nucleoprotein core domain bound to VP35 regulation peptide
|
Categories: Lake Victoria marburgvirus - Ozolin | Large Structures | Dong SS | Guo Y | Li GB | Liu BC | Liu X | Wang WJ | Wang WM