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5x0y
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Complex of Snf2-Nucleosome complex with Snf2 bound to SHL2 of the nucleosome== | |
| + | <SX load='5x0y' size='340' side='right' viewer='molstar' caption='[[5x0y]], [[Resolution|resolution]] 4.69Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5x0y]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C], [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X0Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5X0Y FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.69Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5x0y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x0y OCA], [https://pdbe.org/5x0y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5x0y RCSB], [https://www.ebi.ac.uk/pdbsum/5x0y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5x0y ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||
| - | + | ==See Also== | |
| - | + | *[[Helicase 3D structures|Helicase 3D structures]] | |
| - | + | *[[Histone 3D structures|Histone 3D structures]] | |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </SX> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Saccharomyces cerevisiae S288C]] |
| - | [[Category: Chen | + | [[Category: Synthetic construct]] |
| - | [[Category: Li | + | [[Category: Xenopus laevis]] |
| + | [[Category: Chen Z]] | ||
| + | [[Category: Li M]] | ||
| + | [[Category: Li X]] | ||
| + | [[Category: Liu X]] | ||
| + | [[Category: Xia X]] | ||
Current revision
Complex of Snf2-Nucleosome complex with Snf2 bound to SHL2 of the nucleosome
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